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Advances in the Toxicity Assessment of Silver Nanoparticles Derived from a Sphagnum fallax Extract for Monolayers and Spheroids.
Iskuzhina, Liliya; Batasheva, Svetlana; Kryuchkova, Marina; Rozhin, Artem; Zolotykh, Mariya; Mingaleeva, Rimma; Akhatova, Farida; Stavitskaya, Anna; Cherednichenko, Kirill; Rozhina, Elvira.
Afiliação
  • Iskuzhina L; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Batasheva S; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Kryuchkova M; Institute for Regenerative Medicine, Sechenov University, Trubetskaya Str. 8/2, 119992 Moscow, Russia.
  • Rozhin A; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Zolotykh M; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Mingaleeva R; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Akhatova F; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Stavitskaya A; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml urami 18, 420008 Kazan, Republic of Tatarstan, Russia.
  • Cherednichenko K; Department of Physical and Colloid Chemistry, Gubkin Russian State University of Oil and Gas, 119991 Moscow, Russia.
  • Rozhina E; Department of Physical and Colloid Chemistry, Gubkin Russian State University of Oil and Gas, 119991 Moscow, Russia.
Biomolecules ; 14(6)2024 May 22.
Article em En | MEDLINE | ID: mdl-38927015
ABSTRACT
The production of nanomaterials through environmentally friendly methods is a top priority in the sustainable development of nanotechnology. This paper presents data on the synthesis of silver nanoparticles using an aqueous extract of Sphagnum fallax moss at room temperature. The morphology, stability, and size of the nanoparticles were analyzed using various techniques, including transmission electron microscopy, Doppler laser velocimetry, and UV-vis spectroscopy. In addition, Fourier transform infrared spectroscopy was used to analyze the presence of moss metabolites on the surface of nanomaterials. The effects of different concentrations of citrate-stabilized and moss extract-stabilized silver nanoparticles on cell viability, necrosis induction, and cell impedance were compared. The internalization of silver nanoparticles into both monolayers and three-dimensional cells spheroids was evaluated using dark-field microscopy and hyperspectral imaging. An eco-friendly method for the synthesis of silver nanoparticles at room temperature is proposed, which makes it possible to obtain spherical nanoparticles of 20-30 nm in size with high bioavailability and that have potential applications in various areas of human life.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Extratos Vegetais / Nanopartículas Metálicas Limite: Humans Idioma: En Revista: Biomolecules Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Federação Russa

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Extratos Vegetais / Nanopartículas Metálicas Limite: Humans Idioma: En Revista: Biomolecules Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Federação Russa