Ex-situ machine perfusion in clinical liver transplantation: Current practices and future directions.
Liver Transpl
; 2024 Jul 08.
Article
em En
| MEDLINE
| ID: mdl-38967460
ABSTRACT
Ex-situ machine perfusion of the liver has surmounted traditional limitations associated with static cold storage in the context of organ preservation. This innovative technology has changed the landscape of liver transplantation by mitigating ischemia perfusion injury, offering a platform for continuous assessment of organ quality, and providing an avenue for optimizing use of traditionally marginal allografts. This review summarizes the contemporary clinical applications of machine perfusion devices, and discusses potential future strategies for real-time viability assessment, therapeutic interventions, and modulation of organ function after recovery.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Liver Transpl
/
Liver transplant. (Print)
/
Liver transplantation (Online)
Assunto da revista:
GASTROENTEROLOGIA
/
TRANSPLANTE
Ano de publicação:
2024
Tipo de documento:
Article