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Chitosan-based crosslinking for controlled topical drug release in rhinosinusitis.
Cho, Do-Yeon; Lim, Dong Jin; Kelly, Olivia J; Skinner, Daniel; Zhang, Shaoyan; Jones, Martin P; Grayson, Jessica; Woodworth, Bradford A.
Afiliação
  • Cho DY; Department of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Lim DJ; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Kelly OJ; Division of Otolaryngology, Department of Surgery, Veterans Affairs, Birmingham, Alabama, USA.
  • Skinner D; Department of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Zhang S; Northwestern University, Evanston, Illinois, USA.
  • Jones MP; Department of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Grayson J; Department of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Woodworth BA; Department of Otolaryngology-Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Int Forum Allergy Rhinol ; 2024 Jul 11.
Article em En | MEDLINE | ID: mdl-38990106
ABSTRACT
KEY POINTS Chitosan is a promising drug delivery vector for therapeutics owing to its biocompatibility. Once crosslinked with chitosan, prolonged drug release was noted regardless of hydrophilicity. Hydrophilic drugs may require different strategies to obtain a sustained release profile.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int Forum Allergy Rhinol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int Forum Allergy Rhinol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos