Simulating left atrial arrhythmias with an interactive N-body model.
J Electrocardiol
; 86: 153762, 2024 Jul 22.
Article
em En
| MEDLINE
| ID: mdl-39059214
ABSTRACT
BACKGROUND:
Heart disease and strokes are leading global killers. While atrial arrhythmias are not deadly by themselves, they can disrupt blood flow in the heart, causing blood clots. These clots can travel to the brain, causing strokes, or to the coronary arteries, causing heart attacks. Additionally, prolonged periods of elevated heart rates can lead to structural and functional changes in the heart, ultimately leading to heart failure if untreated. The left atrium, with its more complex topology, is the primary site for complex arrhythmias. Much remains unknown about the causes of these arrhythmias, and computer modeling is employed to study them.METHODS:
We use N-body modeling techniques and parallel computing to build an interactive model of the left atrium. Through user input, individual muscle attributes can be adjusted, and ectopic events can be placed to induce arrhythmias in the model. Users can test ablation scenarios to determine the most effective way to eliminate these arrhythmias.RESULTS:
We set up muscle conditions that either spontaneously generate common arrhythmias or, with a properly timed and located ectopic event, induce an arrhythmia. These arrhythmias were successfully eliminated with simulated ablation.CONCLUSIONS:
We believe the model could be useful to doctors, researchers, and medical students studying left atrial arrhythmias.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Electrocardiol
Ano de publicação:
2024
Tipo de documento:
Article