Circular dichroism observations on the lipoxygenase from reticulocytes.
Biochim Biophys Acta
; 830(2): 136-9, 1985 Aug 08.
Article
em En
| MEDLINE
| ID: mdl-3926001
ABSTRACT
CD spectra of reticulocyte lipoxygenase were recorded at various times during aerobic incubation, which leads to loss of catalytic activity, and after inactivation by the reaction product, 13-LS-hydroperoxylinoleic acid. Neither process showed any correlation with a decrease in the alpha-helix content, which was only observed over much longer times. It is concluded that inactivation of reticulocyte lipoxygenase by the suicidal reaction with 13-LS-hydroperoxylinoleic acid is not accompanied by gross structural alterations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reticulócitos
/
Lipoxigenase
Limite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1985
Tipo de documento:
Article