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The emerging view on the origin and early evolution of eukaryotic cells.
Vosseberg, Julian; van Hooff, Jolien J E; Köstlbacher, Stephan; Panagiotou, Kassiani; Tamarit, Daniel; Ettema, Thijs J G.
Afiliação
  • Vosseberg J; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.
  • van Hooff JJE; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.
  • Köstlbacher S; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.
  • Panagiotou K; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.
  • Tamarit D; Theoretical Biology and Bioinformatics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
  • Ettema TJG; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands. thijs.ettema@wur.nl.
Nature ; 633(8029): 295-305, 2024 Sep.
Article em En | MEDLINE | ID: mdl-39261613
ABSTRACT
The origin of the eukaryotic cell, with its compartmentalized nature and generally large size compared with bacterial and archaeal cells, represents a cornerstone event in the evolution of complex life on Earth. In a process referred to as eukaryogenesis, the eukaryotic cell is believed to have evolved between approximately 1.8 and 2.7 billion years ago from its archaeal ancestors, with a symbiosis with a bacterial (proto-mitochondrial) partner being a key event. In the tree of life, the branch separating the first from the last common ancestor of all eukaryotes is long and lacks evolutionary intermediates. As a result, the timing and driving forces of the emergence of complex eukaryotic features remain poorly understood. During the past decade, environmental and comparative genomic studies have revealed vital details about the identity and nature of the host cell and the proto-mitochondrial endosymbiont, enabling a critical reappraisal of hypotheses underlying the symbiotic origin of the eukaryotic cell. Here we outline our current understanding of the key players and events underlying the emergence of cellular complexity during the prokaryote-to-eukaryote transition and discuss potential avenues of future research that might provide new insights into the enigmatic origin of the eukaryotic cell.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Simbiose / Células Eucarióticas / Evolução Biológica / Eucariotos / Modelos Biológicos Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Simbiose / Células Eucarióticas / Evolução Biológica / Eucariotos / Modelos Biológicos Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda