Expression of interleukin 2 receptors and binding of interleukin 2 by gamma interferon-induced human leukemic and normal monocytic cells.
J Exp Med
; 162(3): 1111-6, 1985 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-3928803
ABSTRACT
Gamma interferon induced surface expression of interleukin 2 (IL-2) receptors on normal human monocytes and the monocytoid cell lines U937 and HL60. These receptors were detected by anti-IL-2 receptor monoclonal antibodies, and U937 IL-2 receptors were indistinguishable from T lymphocyte IL-2 receptors by immunoprecipitation. Also, U937 IL-2 receptors bound biologically active IL-2. These results suggest a role for monocyte IL-2 receptors in T cell/monocyte interaction during an immune response.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Monócitos
/
Receptores Imunológicos
/
Leucemia Mieloide
/
Interferon gama
/
Interleucina-2
Limite:
Humans
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1985
Tipo de documento:
Article