Inhibition of gastric motility induced by activation of the hypothalamic paraventricular nucleus.

ABSTRACT

Electrical stimulation of the paraventricular nucleus depressed the intragastric pressure of adrenalectomized male rats of which gastric movement had been induced by insulin-hypoglycemia. Electrical stimulation to the pituitary stalk produced a similar response in the pressure, but the response was abolished by bilateral lesion of the paraventricular nucleus. These findings allow us to speculate that the paraventricular nucleus is capable of modulating gastric motility, and suggest that the nucleus has a neural connection between the neurohypophysis and the system relevant to visceral function.