Phosphorylase kinase of the liver: deficiency in a girl with increased hepatic glycogen.
Science
; 153(3743): 1534-5, 1966 Sep 23.
Article
em En
| MEDLINE
| ID: mdl-5223147
ABSTRACT
Studies of a child with glycogenosis revealed an increased concentration of glycogen and low phosphorylase activity in her liver. Using mixtures of homogenates of the patient's liver and of normal liver, we found the low phosphorylase activity to be caused by a deficiency of phosphorylase kinase and not of hepatic phosphorylase. The fact that phosphorylase activity was restored to normal values by the addition of phosphorylase b kinase from rabbit muscle substantiates this conclusion.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosforilase Quinase
/
Doença de Depósito de Glicogênio
/
Glucosiltransferases
/
Fígado
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Revista:
Science
Ano de publicação:
1966
Tipo de documento:
Article