Binding studies in the Lurcher mutant suggest an uneven distribution of putative benzodiazepine receptor subclasses in the mouse cerebellum.
Neurosci Lett
; 48(3): 333-8, 1984 Aug 10.
Article
em En
| MEDLINE
| ID: mdl-6091002
ABSTRACT
Binding studies using [3H]flunitrazepam in the cerebellum of normal and Lurcher mutant mice indicate that about 90% of the total benzodiazepine receptor population reside on the Purkinje and granule cells. Moreover, the specific binding of the BZ1 receptor subclass specific ligand [3H]propyl-beta-carboline-3-carboxylate suggests that neuronal elements of the mouse cerebellum other than the Purkinje and granule cells contain about 18% of the BZ1 receptors but only about 7% of the BZ2 receptors of the mouse cerebellum.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzodiazepinas
/
Cerebelo
/
Receptores de GABA-A
Limite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Ano de publicação:
1984
Tipo de documento:
Article