Autoantibodies against neurofilaments in Creutzfeldt-Jakob disease: immunofluorescence in sections of human caudate nucleus.
Acta Virol
; 25(6): 390-4, 1981 Nov.
Article
em En
| MEDLINE
| ID: mdl-6120641
ABSTRACT
Heterospecific autoantibodies to axonal neurofilaments of neurons in sera from five patients with Creutzfeldt-Jakob disease were detected with the use of cryostat section from normal human brain caudate nucleus. The antibody, visualized by the indirect immunofluorescence technique, was shown to bind complement. This allowed to achieve brighter staining either by the anticomplementary method alone or by a combination of both anti-C3 and anti-IgG conjugates
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Autoanticorpos
/
Citoesqueleto
/
Núcleo Caudado
/
Síndrome de Creutzfeldt-Jakob
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Virol
Ano de publicação:
1981
Tipo de documento:
Article