[Is valproic acid teratogenic?]. / L'acide valproïque est-il tératogène?
Rev Neurol (Paris)
; 139(6-7): 445-7, 1983.
Article
em Fr
| MEDLINE
| ID: mdl-6412342
ABSTRACT
In more than 7 000 cases of neonatal malformations processed up to 1982 in a regional computer register 71 infants had been born from epileptic mothers. A significantly higher than expected number of spina bifida aperta were observed in this group, related to the administration to the mother of the anti-epileptic agent valproic acid. A pathogenic hypothesis and a possible preventive procedure for this type of malformation are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Anormalidades Induzidas por Medicamentos
/
Ácido Valproico
/
Meningomielocele
/
Epilepsia
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Infant
/
Newborn
/
Pregnancy
Idioma:
Fr
Revista:
Rev Neurol (Paris)
Ano de publicação:
1983
Tipo de documento:
Article