Rapid radioiodination of rose bengal at room temperature.
J Nucl Med
; 19(5): 525-9, 1978 May.
Article
em En
| MEDLINE
| ID: mdl-641576
ABSTRACT
Published methods for radioiodination of rose bengal require reaction times of 1 hr or more at temperature from 50 to 120 degrees C. Through the use of an acidified ethanol solvent and potassium iodate oxidant, purified rose bengal is radioiodinated at room temperature within 15 min with chemical yields ranging between 93 and 97%. Radiochemical impurities are sufficiently minimized to permit preparation in a single 10-ml serum vial, requiring no additional purification steps. The method reported here is readily adaptable to cold-kit preparation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rosa Bengala
/
Radioisótopos do Iodo
/
Marcação por Isótopo
Idioma:
En
Revista:
J Nucl Med
Ano de publicação:
1978
Tipo de documento:
Article