[Effect of antioxidants on the release of 3H-serotonin by rat brain synaptosomes]. / Deistvie antioksidantov na vybros 3H-serotonina sinaptosomami mozga krys.
Biull Eksp Biol Med
; 96(10): 55-7, 1983 Oct.
Article
em Ru
| MEDLINE
| ID: mdl-6626732
ABSTRACT
The effects of free radical scavengers of different chemical structure (hydroxypyridines, hindered phenols, hydroxyphenothiazines) on processes of 3H-hydroxytryptamine uptake and release by rat brain synaptosomes were studied. All free radical scavengers used inhibited 3T-hydroxytryptamine uptake and stimulated 3H-hydroxytryptamine release, with the efficacy being reduced in the following order 7-hydroxyaminazine greater than butylated hydroxytoluene greater than paginol-2-methyl-6-ethyl-3-hydroxypyridine greater than alpha-tocopherol. The effects of free radical scavengers were eliminated in the presence of EGTA or after cooling to 4 degrees C.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sinaptossomos
/
Serotonina
/
Córtex Cerebral
/
Antioxidantes
Limite:
Animals
Idioma:
Ru
Revista:
Biull Eksp Biol Med
Ano de publicação:
1983
Tipo de documento:
Article