Pharmacokinetic interpretation of some antibiotics in camels.
Arch Int Pharmacodyn Ther
; 261(2): 186-95, 1983 Feb.
Article
em En
| MEDLINE
| ID: mdl-6838280
ABSTRACT
Evaluation of the pharmacokinetic properties of 4 antibiotics penicillin-G (P), streptomycin (S), chloramphenicol (C) and oxytetracycline (O) was performed in groups of camels following a single i.m. injection of therapeutic doses, i.e. 6000 IU, 10, 4 and 3 mg/kg b.wt., respectively. The concentrations of these antibiotics in serum were determined by microbiological assay methods. The highest serum concentrations were reached after 0.42, 1.44, 4.02 and 0.94 hr for P, S, C, and O respectively with corresponding t 1/2 alpha values of 0.12, 0.28, 1.48 and 0.17 hr and t 1/2 beta values of 1.09, 8.28, 6.20 and 7.00 hr.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Camelus
/
Antibacterianos
Limite:
Animals
Idioma:
En
Revista:
Arch Int Pharmacodyn Ther
Ano de publicação:
1983
Tipo de documento:
Article