Free-radical reaction in biological systems.
Ann R Coll Surg Engl
; 62(3): 188-94, 1980 May.
Article
em En
| MEDLINE
| ID: mdl-6994571
ABSTRACT
Free radicals are a highly reactive chemical species which differ from all other species in possessing an unpaired electron. Although free-radical activity in living systems is energetically improbable, recent work suggests that a number of important biological processes depend on it. In contrast to enzymic metabolism these free-radical processes tend to be non-cyclic, irreversible, non-homoeostatic, and energetically wasteful. For the organism as a whole they may nevertheless have considerable survival value. Free radicals are too short-lived to be demonstrable in tissues; but methodological advances are leading to the detection and measurement of characteristic free-radical reaction products. The findings suggest that free-radical activity is not only a potential cause but also a common, perhaps invariable, consequence of cell damage. It is possible that some of the secondary products of free-radical reactions may help to regulate the body's local and systemic response to injury.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxigênio
/
Radicais Livres
Limite:
Humans
Idioma:
En
Revista:
Ann R Coll Surg Engl
Ano de publicação:
1980
Tipo de documento:
Article