Pathologic mechanisms of multifocal choroiditis with retinal detachment after carotid injection of Streptococcus mutans and other bacteria in dogs.
Invest Ophthalmol Vis Sci
; 22(2): 165-73, 1982 Feb.
Article
em En
| MEDLINE
| ID: mdl-7056631
ABSTRACT
Multifocal choroiditis with overlying retinal detachment occurs after carotid injection of certain bacteria in dogs. The ocular lesions occur mainly in the tapetal area of the retina, correlate with microabscesses in the inner choroid and subretinal space, and occasionally occur in the inner retina and anterior uveal tract. The major pathophysiologic factor involved in the dog model of septic choroiditis appears to be embolization of the choriocapillairies by "live" bacteria, which clump and adhere well to tissues. In the dosages used, antibiotics did not prevent or alter the severity of the fundus lesions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Estreptocócicas
/
Descolamento Retiniano
/
Corioidite
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Invest Ophthalmol Vis Sci
Ano de publicação:
1982
Tipo de documento:
Article