Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy.
Science
; 215(4539): 1518-9, 1982 Mar 19.
Article
em En
| MEDLINE
| ID: mdl-7063860
ABSTRACT
Pregnant rats underfed in the first 2 weeks of gestation had offspring with normal body weight at birth and weaning. However, starting at about 5 weeks of age the male offspring became hyperphagic and gained more weight than the controls. The female offspring did not overeat and did not become obese. Both male and female progeny showed increased fat cell size as adults. In males the epididymal and retroperitoneal fat pads were significantly enlarged nd adipocytes in these pads were hypertrophied. In females and fat pads were not enlarged, but adipocytes in the parametrial pads were hypertrophied.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prenhez
/
Tecido Adiposo
/
Distúrbios Nutricionais
/
Obesidade
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Science
Ano de publicação:
1982
Tipo de documento:
Article