Mouse gallbladder emptying by egg yolk: a possible new rapid method for antispasmodic activity evaluation in vivo.
J Pharmacol Methods
; 7(3): 193-5, 1982 May.
Article
em En
| MEDLINE
| ID: mdl-7109644
ABSTRACT
Gallbladder emptying was induced in female albino mice by single oral administrations of 30% lyophylized egg yolk suspension. Mice were killed 15 min later, their gallbladders removed and then weighed. Gallbladder emptying was assessed by comparing weights from control and egg yolk administered mice. The ability of the antispasmodic drugs atropine, N-butylscopolamine, papaverine, trimebutine, dicyclomine, and rociverine to delay gallbladder emptying was determined by administering them either intraperitoneally or orally 7.5 or 15 min prior to egg yolk.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Parassimpatolíticos
/
Gema de Ovo
/
Vesícula Biliar
Limite:
Animals
Idioma:
En
Revista:
J Pharmacol Methods
Ano de publicação:
1982
Tipo de documento:
Article