Effect of estradiol and progesterone on glucosamine 6-phosphate synthase in the uterus of rat.

ABSTRACT

Injection of estradiol to ovariectomised rats caused significant increase in the activity of glucosamine 6-phosphate synthase of uterus. Progesterone did not cause any increase in the activity of the enzyme; however, it antagonised the effect of estradiol. It was observed that the enzyme is predominantly localised in the endometrium of uterus.