Catabolism of 2,4,6-trinitrotoluene by Mycobacterium vaccae.
Appl Microbiol Biotechnol
; 43(5): 937-45, 1995 Oct.
Article
em En
| MEDLINE
| ID: mdl-7576561
ABSTRACT
Mycobacterium vaccae strain JOB-5 cometabolized 2,4,6-trinitrotoluene (TNT) in the presence of propane as a carbon and energy source. Two novel oxidized metabolites, as well as several known reduced products, were generated during catabolism of TNT by M. vaccae. During the cometabolic process, there was transient production of a brown chromophore. This compound was identified as 4-amino-2,6-dinitrobenzoic acid. When M. vaccae was incubated with [14C]TNT and propane, 50% of the added radiolabel was incorporated into the cellular lipid fraction. These results suggest that ring cleavage occurred prior to the incorporation of radiolabelled carbon into phosphatidyl-L-serine, phosphatidylethanolamine, cardiolipin, and other polar lipids.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trinitrotolueno
/
Mycobacterium
Idioma:
En
Revista:
Appl Microbiol Biotechnol
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Estados Unidos