Mate preference and avoidance in female rats following treatment with scopolamine.
Physiol Behav
; 58(1): 97-100, 1995 Jul.
Article
em En
| MEDLINE
| ID: mdl-7667434
ABSTRACT
The effects of the muscarinic antagonist, scopolamine, on the behavior of female rats in a mate preference test were determined. Ovariectomized rats were primed with sufficient doses of estradiol benzoate (0.25 micrograms for 3 days) and progesterone (500 micrograms) to activate full sexual receptivity. Beginning 15 min after intraperitoneal injection of saline (0.4 ml/kg) or scopolamine hydrochloride (1 mg/kg), females were tested in an arena divided into three compartments. Females treated with scopolamine clearly avoided a compartment occupied by a gonadally intact stimulus male, instead preferring a compartment occupied by a castrated male or an empty neutral compartment. Direct contact with an intact male was a critical feature of this avoidance because females treated with scopolamine did not avoid intact males that were confined within a chamber that prevented physical contact between the male and female. Results indicate that female rats treated with scopolamine avoid direct physical contact with sexually active males, possibly due to an alteration in sexual motivation and/or the aversive nature of this interaction.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Escopolamina
/
Comportamento Sexual Animal
/
Meio Social
/
Comportamento de Escolha
Limite:
Animals
Idioma:
En
Revista:
Physiol Behav
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Estados Unidos