Rab GTPases: master regulators of membrane trafficking.
Curr Opin Cell Biol
; 6(4): 522-6, 1994 Aug.
Article
em En
| MEDLINE
| ID: mdl-7986528
ABSTRACT
Rab GTPases are thought to be likely to catalyze the accurate association of pairs of targeting molecules located on the surfaces of transport vesicles with their corresponding membrane acceptors. Advances during the past year have solidified our understanding of the mechanisms by which Rab proteins are recruited onto nascent transport vesicles and retrieved from their fusion targets. Functional analyses of Rab proteins in living cells have led to the surprising observation that vesicles do not seem to form if the appropriate Rab protein, in its GTP-bound conformation, is not present.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligopeptídeos
/
Proteínas de Ligação ao GTP
/
Alquil e Aril Transferases
/
Proteínas rab de Ligação ao GTP
/
GTP Fosfo-Hidrolases
Limite:
Animals
Idioma:
En
Revista:
Curr Opin Cell Biol
Ano de publicação:
1994
Tipo de documento:
Article