A novel human gene that is preferentially transcribed in heart muscle.
Gene
; 144(2): 301-6, 1994 Jul 08.
Article
em En
| MEDLINE
| ID: mdl-8039717
ABSTRACT
We have cloned a human cDNA fragment for a gene that is expressed primarily in the heart. To explore its biological function, we have isolated full-length cDNA clones of the gene. DNA sequencing of the 2.7-kb cDNA revealed a 2274-bp ORF. Close to the N terminus of the deduced amino acid sequence is a possible ATP-binding domain that has been assembled by a fusion of B- and A-type adenine nucleotide-binding motifs. In the middle of the sequence is a long stretch of alpha-helical residues that could form a coiled-coil. These features imply that this is a sequence encoding a new human motor protein.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transcrição Gênica
/
Proteínas Musculares
/
Miocárdio
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Gene
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Japão