Endoreduplication and telomeric association in a choroid plexus carcinoma.
Cancer Genet Cytogenet
; 87(1): 7-10, 1996 Mar.
Article
em En
| MEDLINE
| ID: mdl-8646745
ABSTRACT
Cytogenetic studies showed a hyperhaploid stemline, (32,XY,+1,+7,+9,+12,+13,+14,+19,+20) in a patient with choroid plexus carcinoma. Endoreduplication and doubling of the stemline to 200-400 chromosomes per cell and variation in numerical changes were also noted. Telomeric association was present in most cells. The 12p and 20q were by far the most frequently involved chromosome arms. Telomeric association is believed to have triggered further structural changes in this case since the 12p and 20q were always involved in the few structural abnormalities identified. A review of the literature suggests that hyperhaploidy may characterize choroid plexus carcinoma and hyperdiploidy choroid plexus papilloma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aberrações Cromossômicas
/
Telômero
/
Neoplasias do Plexo Corióideo
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Cancer Genet Cytogenet
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Canadá