New variant Ph translocation in chronic myeloid leukemia: t(Y;22)(p11;q11).
Cancer Genet Cytogenet
; 87(1): 75-8, 1996 Mar.
Article
em En
| MEDLINE
| ID: mdl-8646747
ABSTRACT
A 4-year-old boy with chronic myeloid leukemia (CML) was shown to have a variant Ph t(Y;22)(p11;q11). To our knowledge, this is the first report of a variant Ph translocation involving Y. Molecular analysis showed that the breakpoint on chromosome 22 is in the breakpoint cluster region (bcr), typical of CML with the classic t(9;22), suggesting that it might be a complex Ph translocation with the involvement of 9q34.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomo Y
/
Cromossomos Humanos Par 22
/
Cromossomo Filadélfia
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
Limite:
Child, preschool
/
Humans
/
Male
Idioma:
En
Revista:
Cancer Genet Cytogenet
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Argentina