[Proof of drug hypersensitivity using an in vivo leukocyte migration inhibition test]. / Nachweis der arzneimittelüberempfindlichkeit mit einem in-vivo-leukozytenmigrationshemmtest
Z Gesamte Inn Med
; 32(5): 123-5, 1977 Mar 01.
Article
em De
| MEDLINE
| ID: mdl-868183
ABSTRACT
22 chloramphenicol allergics, 10 penicillin allergics and 6 patients with a chromate eczema as well as altogether 34 non-allergic control persons with healthy skin were examined according to the skin chamber method. After addition of the adequate antigen (chloramphenicol, penicillin, ammonium bichromate) into one of the two simultaneously applied skin chambers in sensitized persons an inhibition of the leucocyte migration in the antigen chamber develops. The polymorphonuclear neutrophilic granulocytes mobilised into the inflammation field were regarded as indicator cells. 5 chloramphenicol allergics with eczematous skin abnormalities and all control persons were negative. The investigation method is simply to be performed and therefore it is particularly suitable for clinical routine work.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibição de Migração Celular
/
Hipersensibilidade a Drogas
/
Leucócitos
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
De
Revista:
Z Gesamte Inn Med
Ano de publicação:
1977
Tipo de documento:
Article