Comparative killing kinetics of methicillin-resistant Staphylococcus aureus by bacitracin or mupirocin.
Infect Control Hosp Epidemiol
; 17(3): 178-80, 1996 Mar.
Article
em En
| MEDLINE
| ID: mdl-8708360
ABSTRACT
The in vitro activities of bacitracin and mupirocin were compared for seven different strains of methicillin-resistant Staphylococcus aureus. Six of seven strains showed bacitracin minimum inhibitory concentrations (MICs) of 0.5 to 1.0 units/mL, and all seven had mupirocin MICs of 0.5 to 2 micrograms/mL. Time-kill studies revealed 2.6- to 4.5-log reduction in 24 hours with strains susceptible to bacitracin (4 units/mL) and 0 to 2.2 reduction with mupirocin (16 micrograms/mL). Bacitracin should be considered further for in vivo studies because of enhanced bacteriocidal effect and lower cost.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
/
Bacitracina
/
Resistência a Meticilina
/
Mupirocina
/
Anti-Infecciosos Locais
/
Antibacterianos
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Infect Control Hosp Epidemiol
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
ENFERMAGEM
/
EPIDEMIOLOGIA
/
HOSPITAIS
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos