Fulminant hepatitis after carbimazole and propranolol administration.
Eur J Gastroenterol Hepatol
; 8(3): 287-8, 1996 Mar.
Article
em En
| MEDLINE
| ID: mdl-8724032
ABSTRACT
We report the case of a patient who developed jaundice, encephalopathy, a marked increase in serum aminotransferase activity and a decrease in prothrombin and proaccelerin levels, after 6 weeks' treatment with carbimazole and propranolol for hyperthyroidism. The patient ultimately underwent orthotopic liver transplantation. This case strongly suggests that carbimazole may occasionally induce fulminant hepatitis and that careful monitoring of liver enzymes may be useful during the treatment of hyperthyroidism with this drug.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Propranolol
/
Antitireóideos
/
Carbimazol
/
Encefalopatia Hepática
/
Antagonistas Adrenérgicos beta
/
Doença Hepática Induzida por Substâncias e Drogas
/
Icterícia
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Eur J Gastroenterol Hepatol
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
França