Biometrological assessment of the preventive effect of a miconazole spray powder on athlete's foot.
Clin Exp Dermatol
; 21(5): 344-6, 1996 Sep.
Article
em En
| MEDLINE
| ID: mdl-9136152
ABSTRACT
Prevention of athlete's foot is a difficult problem. Using non-invasive biometrological methods, we evaluated the changes induced in the stratum corneum by a 3-week treatment with miconazole spray powder. A total of 16 athletes apparently at risk of developing tinea pedis, but without any evidence for the disease at the time of inclusion, participated in the study. They applied the medicated powder to one foot daily, while the other foot remained untreated to serve as a control. No adverse events occurred. In comparison with the control site, the capacitance of the toeweb skin was significantly reduced by the treatment. The ex vivo bioassay of dermatophyte culture on stratum corneum demonstrated a significant inhibition of growth of Trichophyton mentagrophytes var. interdigital at the treated site. The results of this study provide indirect evidence that the regular use of miconazole spray powder decreases the risk of developing athlete's foot.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tinha dos Pés
/
Miconazol
/
Antifúngicos
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Bélgica