Vinyl chloride-induced depression of hepatic non-protein sulfhydryl content and effects on bromosulphalein (BSP) clearance in rats.
Toxicology
; 6(1): 1-8, 1976 Jun.
Article
em En
| MEDLINE
| ID: mdl-941158
ABSTRACT
Rats were exposed to atmospheres of 2000, 1000, 250, 150, 50 and 10 ppm vinyl chloride (VC) for 1-7 h to determine the effect of VC on the hepatic non-protein sulhydryl content, Exposure to 2000, 1000, 250 and 150 ppm VC caused a progressive depression of the hepatic non-protein sulfhydryl content. Following exposure to 50 ppm VC for 7 h the depression was inconsistent, and no depression was observed after 10 ppm VC for 7 h. Also, exposure to 1000 ppm VC did not alter the serum clearance of bromosulphalein (BSP).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Sulfidrila
/
Sulfobromoftaleína
/
Cloreto de Vinil
/
Compostos de Vinila
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
Toxicology
Ano de publicação:
1976
Tipo de documento:
Article