Environmental stimulation reduces learning deficits in experimental cretinism.
Science
; 191(4227): 578-9, 1976 Feb 13.
Article
em En
| MEDLINE
| ID: mdl-943127
ABSTRACT
Behavioral deficits in adult rats exposed perinatally to thiouracil were substantially reduced or elimated by a 5-week period of "superenriched" postweaning rearing conditions before testing. This treatment resulted in remediation of hypothyroid rats' deficits in maze learning, maze retention, and resistance to extinction of bar-pressing; the facilitative effect persisted for more than 4 months. These behavioral results were consistent with neurohistological findings from studies of early thyroid deficiency and postweaning environmental stimulation in rats.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipotireoidismo Congênito
/
Modelos Animais de Doenças
/
Meio Ambiente
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Science
Ano de publicação:
1976
Tipo de documento:
Article