CD43 is associated with tyrosine kinase activity in human neutrophils.
J Leukoc Biol
; 64(6): 800-2, 1998 Dec.
Article
em En
| MEDLINE
| ID: mdl-9850163
ABSTRACT
CD43 appears to be involved in signal transduction, however, the mechanism of this function is unknown. Protein kinase activity was detected in neutrophils associated with CD43. Most of the protein kinase activity associated with these antigens was tyrosine kinase activity. The src family kinases lyn and hck were found to account for much of the associated tyrosine kinase activity. The data suggest that associated tyrosine kinase activity may play a role in signal transduction via CD43 to regulate other cell functions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sialoglicoproteínas
/
Proteínas Tirosina Quinases
/
Antígenos CD
/
Neutrófilos
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
J Leukoc Biol
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Estados Unidos