This study is an ongoing
cross sectional survey aimed at determining factors associated with
HIV infection in
HIV-infected
heterosexuals and
bisexuals and their
heterosexual partners.
HIV-positive
patients (index cases) were recruited when they attended the Queen's Park Counselling Centre and Clinic, the main clinic for
sexually transmitted diseases in
Trinidad. All subjects were required to give signed consent to participate in the study and respond to a
questionnaire administered by an
interviewer. Both
partner notification (index cases refer partners) and provider
notification (contact tracers locate partners) were used. A partner was defined as one
who had had
sexual intercourse with the index case up to 5 years preceding the
interview. On enrolment, partners were counselled and offered an
HIV test and a
medical examination. Samples were screened by
ELISA for
HIV antibody and repeatedly reactive samples were confirmed, using
immunofluorescence assay or
Western Blot. Between September 14, 1992 and October 8, 1993, 192 index cases and 50 partners had been enrolled. Recruitment of partners was a challenge as the prospect of
notification caused
anxiety for many
patients. Overall,
HIV seroprevalence of
sexual partners was 54 percent (27/50) and
HIV seropositivity was significantly (p<0.05) associated with
history of
STDs and
prostitution within the last 2 years.
Genital ulcer diseases may be another
risk factor (p<0.10).
Cocaine use, though not itself associated with
HIV seropositivity, was significantly associated with 2 of the 3 proposed
risk factors, and may
play an indirect
role in
HIV transmission (AU)