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1.

Neurons dispose of hyperactive kinesin into glial cells for clearance.

Xie, Chao; Chen, Guanghan; Li, Ming; Huang, Peng; Chen, Zhe; Lei, Kexin; Li, Dong; Wang, Yuhe; Cleetus, Augustine; Mohamed, Mohamed Aa; Sonar, Punam; Feng, Wei; Ökten, Zeynep; Ou, Guangshuo.

EMBO J ; 2024 May 28.

Artículo en Inglés | MEDLINE | ID: mdl-38806659

2.

The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick.

Cleetus, Augustine; Merck, Georg; Mueller-Planitz, Felix; Ökten, Zeynep.

Proc Natl Acad Sci U S A ; 119(33): e2109378119, 2022 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-35947619

3.

DYF-5/MAK-dependent phosphorylation promotes ciliary tubulin unloading.

Jiang, Xuguang; Shao, Wenxin; Chai, Yongping; Huang, Jingying; Mohamed, Mohamed A A; Ökten, Zeynep; Li, Wei; Zhu, Zhiwen; Ou, Guangshuo.

Proc Natl Acad Sci U S A ; 119(34): e2207134119, 2022 08 23.

Artículo en Inglés | MEDLINE | ID: mdl-35969738

4.

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.

Xie, Chao; Li, Liuju; Li, Ming; Shao, Wenxin; Zuo, Qingyu; Huang, Xiaoshuai; Chen, Riwang; Li, Wei; Brunnbauer, Melanie; Ökten, Zeynep; Chen, Liangyi; Ou, Guangshuo.

EMBO J ; 39(12): e103955, 2020 06 17.

Artículo en Inglés | MEDLINE | ID: mdl-32338401

5.

Reconstitution reveals motor activation for intraflagellar transport.

Mohamed, Mohamed A A; Stepp, Willi L; Ökten, Zeynep.

Nature ; 557(7705): 387-391, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29743676

6.

Molecular underpinnings of cytoskeletal cross-talk.

Oberhofer, Angela; Reithmann, Emanuel; Spieler, Peter; Stepp, Willi L; Zimmermann, Dennis; Schmid, Bettina; Frey, Erwin; Ökten, Zeynep.

Proc Natl Acad Sci U S A ; 117(8): 3944-3952, 2020 02 25.

Artículo en Inglés | MEDLINE | ID: mdl-32041870

7.

Torque generation of kinesin motors is governed by the stability of the neck domain.

Brunnbauer, Melanie; Dombi, Renate; Ho, Thi-Hieu; Schliwa, Manfred; Rief, Matthias; Ökten, Zeynep.

Mol Cell ; 46(2): 147-58, 2012 Apr 27.

Artículo en Inglés | MEDLINE | ID: mdl-22541555

8.

Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro.

Oberhofer, Angela; Spieler, Peter; Rosenfeld, Yuliya; Stepp, Willi L; Cleetus, Augustine; Hume, Alistair N; Mueller-Planitz, Felix; Ökten, Zeynep.

Proc Natl Acad Sci U S A ; 114(24): E4714-E4723, 2017 06 13.

Artículo en Inglés | MEDLINE | ID: mdl-28559319

9.

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.

Xie, Chao; Li, Liuju; Li, Ming; Shao, Wenxin; Zuo, Qingyu; Huang, Xiaoshuai; Chen, Riwang; Li, Wei; Brunnbauer, Melanie; Ökten, Zeynep; Chen, Liangyi; Ou, Guangshuo.

EMBO J ; 39(18): e106366, 2020 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-33433002

10.

Kinesin-2 motors adapt their stepping behavior for processive transport on axonemes and microtubules.

Stepp, Willi L; Merck, Georg; Mueller-Planitz, Felix; Ökten, Zeynep.

EMBO Rep ; 18(11): 1947-1956, 2017 11.

Artículo en Inglés | MEDLINE | ID: mdl-28887322

11.

A non-mitotic CENP-E homolog in Dictyostelium discoideum with slow motor activity.

Kösem, Süleyman; Ökten, Zeynep; Ho, Thi-Hieu; Trommler, Gudrun; Koonce, Michael P; Samereier, Matthias; Müller-Taubenberger, Annette.

Biochem Biophys Res Commun ; 431(3): 490-5, 2013 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-23333327

12.

Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner.

Brunnbauer, Melanie; Mueller-Planitz, Felix; Kösem, Süleyman; Ho, Thi Hieu; Dombi, Renate; Gebhardt, J Christof M; Rief, Matthias; Okten, Zeynep.

Proc Natl Acad Sci U S A ; 107(23): 10460-5, 2010 Jun 08.

Artículo en Inglés | MEDLINE | ID: mdl-20498083

13.

The lever arm effects a mechanical asymmetry of the myosin-V-actin bond.

Gebhardt, J Christof M; Okten, Zeynep; Rief, Matthias.

Biophys J ; 98(2): 277-81, 2010 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-20338849

14.

Kinesin-2 from C. reinhardtii Is an Atypically Fast and Auto-inhibited Motor that Is Activated by Heterotrimerization for Intraflagellar Transport.

Sonar, Punam; Youyen, Wiphu; Cleetus, Augustine; Wisanpitayakorn, Pattipong; Mousavi, Sayed I; Stepp, Willi L; Hancock, William O; Tüzel, Erkan; Ökten, Zeynep.

Curr Biol ; 30(6): 1160-1166.e5, 2020 03 23.

Artículo en Inglés | MEDLINE | ID: mdl-32142698

15.

Myosin VI walks hand-over-hand along actin.

Okten, Zeynep; Churchman, L Stirling; Rock, Ronald S; Spudich, James A.

Nat Struct Mol Biol ; 11(9): 884-7, 2004 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-15286724

16.

Resolving kinesin stepping: one head at a time.

Stepp, Willi L; Ökten, Zeynep.

Life Sci Alliance ; 2(5)2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31601622

17.

Molecular motors: a step dissected.

Okten, Zeynep; Schliwa, Manfred.

Nature ; 450(7170): 625-6, 2007 Nov 29.

Artículo en Inglés | MEDLINE | ID: mdl-18046391

18.

In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.

Heym, Roland G; Zimmermann, Dennis; Edelmann, Franziska T; Israel, Lars; Ökten, Zeynep; Kovar, David R; Niessing, Dierk.

J Cell Biol ; 203(6): 971-84, 2013 Dec 23.

Artículo en Inglés | MEDLINE | ID: mdl-24368805

19.

How kinesin-2 forms a stalk.

Vukajlovic, Marija; Dietz, Hendrik; Schliwa, Manfred; Ökten, Zeynep.

Mol Biol Cell ; 22(22): 4279-87, 2011 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-21917588

20.

Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensable.

Zimmermann, Dennis; Abdel Motaal, Basma; Voith von Voithenberg, Lena; Schliwa, Manfred; Ökten, Zeynep.

PLoS One ; 6(9): e25473, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21966532

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Neurons dispose of hyperactive kinesin into glial cells for clearance.

The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick.

DYF-5/MAK-dependent phosphorylation promotes ciliary tubulin unloading.

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.

Reconstitution reveals motor activation for intraflagellar transport.

Molecular underpinnings of cytoskeletal cross-talk.

Torque generation of kinesin motors is governed by the stability of the neck domain.

Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro.

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.

Kinesin-2 motors adapt their stepping behavior for processive transport on axonemes and microtubules.

A non-mitotic CENP-E homolog in Dictyostelium discoideum with slow motor activity.

Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner.

The lever arm effects a mechanical asymmetry of the myosin-V-actin bond.

Kinesin-2 from C. reinhardtii Is an Atypically Fast and Auto-inhibited Motor that Is Activated by Heterotrimerization for Intraflagellar Transport.

Myosin VI walks hand-over-hand along actin.

Resolving kinesin stepping: one head at a time.

Molecular motors: a step dissected.

In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.

How kinesin-2 forms a stalk.

Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensable.