Trends in reader access and article processing charges among urology journals: A systematic review.

Introduction: This bibliometric study is designed to investigate the relations of urology journals with access types and article processing charges (APCs) to assess the changing paradigm in urology publishing. Methods: The three major databases: The Master Journal List directory by Clavirate Analytics, Scopus® and PubMed were queried for relevant journals in urology and subspecialties. Characterization of urology journals was undertaken, and citation metrics and APCs were compared across access types. A partial sampling was used to investigate the number of open access (OA) articles according to access types and correlations with both APCs and CiteScore. Results: Seventy-seven journals were included into the study. Gold and diamond OA journals comprised 35.4% of urology journals in 2009 and were increased to 49.3% in 2022. No significant difference was found for change in the CiteScore of 2017 and 2021 between the access types, F (2,63) = 0.152, P = 0.859, η2 = 0.005. A moderate positive correlation was found between APCs and CiteScore for both hybrid (rs [27] =0.431, P < 0.0005) and gold OA (rs [27] =0.489, P = 0.007) journals. The authors need to pay $1175 more to publish their articles in OA model in hybrid journals. The number of articles published in OA model by hybrid journals were not correlated with APCs (rs = 0.332, P = 0.078) but correlated with CiteScore (rs = 0.393, P = 0.035). Conclusions: A paradigm shift in urology publishing toward OA model has been occurring. Authors choose prestige, OA model, rapid publication, and less rigorous peer-review to publish their articles. APCs bear only moderate correlation with the citation metrics of the urology journals.

The relationship between anthropometric and metabolic risk factors and testicular function in healthy young men.

OBJECTIVE: This study investigated the relationship of anthropometric and metabolic risk factors with seminal and sex steroidal hormone parameters in a screened population of healthy males. METHODS: The participants were healthy young men without chronic or congenital diseases. The body composition parameters that we investigated were measured weight, height, and waist circumference (WC), as well as bioelectrical impedance analysis. Semen samples were analyzed for semen volume, sperm concentration, sperm motility and morphology, seminal pH, and liquefaction time. Biochemistry analysis, including glucose and lipid metabolism parameters, was conducted on fasting blood samples. Testicular volume was calculated separately for each testis using ultrasonography. RESULTS: Body mass index exhibited an inverse association with total sperm count. WC showed negative correlations with numerous seminal parameters, including sperm concentration, total sperm count, sperm morphology, and follicle-stimulating hormone levels. The basal metabolic rate was associated with seminal pH, liquefaction time, and sperm motility. WC, fat mass percentage, and triglyceride levels exhibited negative correlations with sex hormone binding globulin. The measures of glucose metabolism were associated with a greater number of seminal parameters than the measures of cholesterol metabolism. C-reactive protein levels were inversely associated with sperm concentration and total sperm count. CONCLUSION: Anthropometric and metabolic risk factors were found to predict semen quality and alterations in sex steroidal hormone levels.

The Association of Postvoiding Residual Volume, Uroflowmetry Parameters and Bladder Sensation.

PURPOSE: To investigate whether postvoiding residual bladder volume (PVR) and uroflowmetry parameters associate with bladder sensation in male patients with bladder outlet obstruction (BOO) and to find out the reliable time of these examinations. MATERIALS AND METHODS: Sixty men with bladder outlet obstruction underwent transabdominal ultrasound in order to measure postvoiding residual volume and uroflowmetry. At the first day, PVR was measured while the patients had mild bladder sensation. Patients emptied their bladder during uroflowmetry. The next day, same patients underwent a second uroflowmetry and PVR measurement while the patients had severe bladder sensation. The first and next day PVR and uroflowmetry parameters were compared and their correlation with lower urinary tract symptoms (LUTS) were analysed. RESULTS: The mean age of the subjects was 69.7 ± 8.6 years. PVR measured at the first day while patients had mild bladder sensation was significantly found lower than the next day PVR (mean ± SD: 80.79 ± 72.18 vs 158 ± 115.82, p<0.001) and correlated with LUTS (rs =0.38, p=0.012). In contrary, uroflowmetry parameters at severe sensation of bladder (mean ± SD: Qmax:13.53 ± 6.32; Qave:5.32 ± 2.31) showed correlation with LUTS (rs = -0.492, p= 0.001). CONCLUSIONS: PVR measurement at mild bladder sensation correlates with LUTS and should be performed in the evaluation of male patients with BOO. However, uroflowmetry is advised to be performed when the patient has severe bladder sensation.

The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats.

PURPOSE: The aim of this experimental study was to investigate the antioxidant effects of astaxanthin against cisplatin-induced nephrotoxicity in rats. METHODS: Forty-eight male Sprague-Dawley rats weighing 264.83 ±â€¯7.39 g were randomly divided into six groups of eight animals each. These were constituted as control, olive oil control, astaxanthin control, cisplatin control, 16 mg/kg cisplatin & 25 mg/kg astaxanthin and 16 mg/kg cisplatin & 75 mg/kg astaxanthin groups. Biochemical evaluation was performed by measuring blood urea nitrogen, serum creatinine, total oxidant status and total antioxidant status. Renal corpuscle, proximal and distal tubules areas (µm2) were calculated for histopathological evaluation, and Caspase-3 staining was performed for immunohistochemical evaluation. RESULTS: Cisplatin reduced total antioxidant status levels and increased blood urea nitrogen, serum creatinine, total oxidant status, and Caspase-3 levels. It also caused dilatation, vacuolization, and loss of tubular epithelial cells in the proximal and distal tubules, and glomerular degeneration and edema were determined in kidney tissue (p < 0.05). Administration of 25 mg and 75 mg astaxanthin increased total antioxidant status levels, reduced blood urea nitrogen, serum creatinine, total oxidant status, and Caspase-3, and ameliorated degenerative distal and proximal tubules, glomerular degeneration and edema in kidney tissue (p < 0.05). CONCLUSIONS: The nephrotoxic effect of cisplatin was diminished by the antioxidant effect of astaxanthin.

The Effect of Different Metabolic Syndrome: Definitions on the Relationship Between Metabolic Syndrome and LUTS in Men With Benign Prostatic Enlargement.

Because various criteria are used to define metabolic syndrome (MetS), this study examines the most relevant definition for patients with benign prostatic enlargement (BPE). Most studies regarding the link between MetS and BPE/lower urinary tract symptoms (LUTS) have used the National Cholesterol Education Program Adult Treatment Panel III criteria for diagnosis, while a few have used criteria from the International Diabetes Federation and/or American Heart Association. Patients with LUTS due to BPE are classified as having MetS or not by the aforementioned three definitions. Prostate volume, International Prostate Symptom Score, storage and voiding subscores, maximum urinary flow rate, and the postvoid urine of patients with and without MetS were compared separately in the three different groups. Surgical and medical treatment prevalence was also compared between three groups. No matter which definition was used, the International Prostate Symptom Score, the storage and voiding symptom scores, prostate volume, prostate-specific antigen, and postvoid urine were significantly higher in the patients with MetS. The maximum urinary flow rate was similar between patients with and without MetS, according to all three different definitions. There was no significant difference in the aforementioned parameter between patients with MetS diagnosed with the three different definitions. Irrespective of which definition was used, the surgical treatment rate was not significantly different in patients diagnosed with than without MetS, or between the patients with MetS diagnosed with the three different definitions. The authors suggest that it does not matter which of the aforementioned three definitions is used during the evaluation of MetS in men with BPE/LUTS.

CT-Based Determination of Ureteral Stone Volume: A Predictor of Spontaneous Passage.

INTRODUCTION AND OBJECTIVES: Which ureteral stone can pass spontaneously? It is hard to answer this question exactly. The size and location of the stone are the most important predictors. However, there is still a considerable gray zone that needs to be clarified. We try to identify the role of stone volume (SV) in the prediction of spontaneous passage (SP). MATERIALS AND METHODS: Seventy-eight patients with a solitary ureteral stone were retrospectively evaluated. Ureter SV measurements were taken in three planes and were calculated using the following formula: V = (X) × (Y) × (Z) × 0.52. SVs, and the longest diameters (LDs) were compared between patients who passed stones spontaneously and those who needed intervention. RESULTS: The SVs and LDs were significantly lower in patients who passed stones spontaneously than in patients who required intervention (41.2 ± 35.5 vs 128.1 ± 91.1 mm(3), p = 0.001; 5.7 ± 1.8 vs 7.4 ± 1.7 mm, p = 0.001). The optimum cutoff values were 7.0 mm and 52.6 mm(3) for the LD and SV, respectively. For those stones of ≤7 mm, the volumes of the stones that could and could not pass did not differ significantly. However, the volume of the stones >7.0 mm that could pass was significantly higher than of those that could not. SP was 30.6% for stones >7 mm; however, when we removed the stones >52.6 mm(3), SP increased to 75% for stones higher than 7 mm (p = 0.001). CONCLUSIONS: To classify ureteral stones using only one parameter such as stone diameter may lead to heterogeneity within the group. SV may be used in addition to size to determine a more definite homogeneous group to predict SP more precisely.

Testis sparing surgery in a case of small unilateral testicular cancer.

A 22-year-old male presented at our institution with an incidentally ultrasound-detected testicular tumor. Magnetic resonance imaging showed a contrast-enhanced right intratesticular mass over 1 cm in size. The patient underwent testis sparing surgery. Pathologic examination revealed seminoma. A follow-up nine months later showed no residual tumor, a normal contour of the testis and no evidence of atrophy. Testis sparing surgery is an option for patients with small unilateral testicular tumors even in the presence of a healthy contralateral testis.

Increased bladder wall thickness in diabetic and nondiabetic women with overactive bladder.

PURPOSE: Bladder wall thickness has been reported to be associated with overactive bladder (OAB) in women. Diabetic women have an increased risk for OAB syndrome and may have an increased risk for bladder wall thickness. METHODS: A total of 235 female patients aged 40 to 75 years were categorized into four groups. The first group consisted of women free of urgency or urge urinary incontinence. The second group included nondiabetic women with idiopathic OAB. The third group consisted of women with diabetes and clinical OAB, and women with diabetes but without OAB constituted the fourth group. Bladder wall thickness at the anterior wall was measured by ultrasound by the suprapubic approach with bladder filling over 250 mL. RESULTS: The diabetic (third group) and nondiabetic (second group) women with OAB had significantly greater bladder wall thickness at the anterior bladder wall than did the controls. However, the difference was not significant between the diabetic (third group) and the nondiabetic (second group) women with OAB. Women with diabetes but without OAB (fourth group) had greater bladder wall thickness than did the controls but this difference was not significant. Additionally, the difference in bladder wall thickness between diabetic women with (third group) and without (fourth group) OAB was not significant. CONCLUSIONS: This is the first study to show that bladder wall thickness is increased in diabetic women with and without OAB. Additionally, nondiabetic women with OAB had increased bladder wall thickness. Further studies may provide additional information for diabetic and nondiabetic women with OAB, in whom the etiopathogenesis of the disease may be similar.