[Global study on tobacco use among youth 13-15 years old in the Russian Federation: dynamic surveillance 2004-2021].

The article is devoted to the analysis of the results of the global surveys among youth 13-15 years old on tobacco consumption, conducted in 2004, 2015, 2021 in Khabarovsk, Novosibirsk, Cheboksary, Moscow, Pskov and the Russian Federation. The dynamics and trends in consumption of tobacco, electronic nicotine delivery systems (ENDS) and heated tobacco products (HTPs) are analyzed. MATERIALS AND METHODS: The surveys used representative samples formed on the basis of all public schools. In 2004, 2015 and 2021 regional sampling included two stages. In 2021 national sampling included three stages: the selection of municipalities, schools and classes. All students of the selected classes were asked. The surveys used the same questionnaire. The total number of respondents - 38 345, the overall response rate - more than 90%. RESULTS: In the Russian Federation, in 2004-2021 among students aged 13-15, the prevalence of tobacco consumption decreased from 27.3 to 11.0%, passive smoking in homes from 76.4 to 23.1%, in closed public places from 89.4 to 23.7%. The consumption of ENDS and HTPs increased up to 16.7 and 3.5% respectively. Similar trends in consumption of products, passive smoking were identified in all the cities. CONCLUSION: The adoption in 2013 of the Federal Law "On protecting the health of citizens from the effects of second hand tobacco smoke, the consequences of tobacco consumption or the consumption of nicotine-containing products" had a significant impact on tobacco use by adolescents and reduced the prevalence of tobacco consumption and passive smoking among them by 3 times.

Survival of Mesenchymal Stem Cells in Different Methods of Nebulization.

We compared survival of bone marrow mesenchymal stem cells after compressor, ultrasound, and mesh nebulization of the cell suspension over 10 min. Viability of stromal cells was best preserved after compressor nebulization (72%). Cell survival after ultrasonic nebulization was significantly lower (20%). After mesh nebulization, no live cells were found. Thus, compressor nebulization is the most preferable method of the production of cell aerosol for their delivery to the lower respiratory tract.

[Respiratory tract damage in those who cleaned up the aftermath of the accident at the Chernobyl Atomic Electric Power Station]. / Porazhenie respiratornogo trakta u likvidatorov posledstvii avarii na Chernobyl'skoi AES.

The authors have established the fact of acute inhalation damage of the "Chernobyl aerosol" to respiratory organs of the exposed subjects. The complaints correlation to the site of work, time and kind of job shows that respiratory symptoms arose more frequently in those members of emergency teams who arrived at the station in May, August-October 1986, March 1987, stayed for 30-40 days, worked at the site of the damaged reactor, were engaged in decontamination, degasification, drilling, construction and other "dusty" jobs. As a result of inhalation of the Chernobyl dust previously healthy patients developed various respiratory diseases.

[The prevalence of respiratory organ diseases among those who cleaned up the accident at the Chernobyl Atomic Electric Power Station]. / Rasprostranennost' zabolevanii organov dykhaniia sredi likvidatorov avarii na Chernobyl'skoi AES.

Epidemiological investigation of 206 males aged 30-45 exposed to radiation while working from May 1986 to March 1987 (the period of most likely radioactive dust inhalation damage) in radionuclide-contaminated zone after the Chernobyl accident has been performed. Chronic bronchitis and bronchial asthma occurred in the examinees 4.1 and 7.1 times more frequently than in nonexposed controls. The exposure to radionuclides was found related to subsequent respiratory disorders. Bronchopulmonary diseases in the emergency crews exposed to radiation were encountered in 42.5% which is two times more frequently than in control subjects. In view of this, it is necessary to introduce urgently special prophylactic programs for the above subjects.

Lungs exposed to nuclear catastrophe: one-year therapeutic programme in Chernobyl liquidators group.

The high prevalence of chronic respiratory problems in cleaning technicians (so-called "liquidators") of the destroyed reactor at Chernobyl and prolonged persistence of inhaled radioactive particles in their lungs suggested a substantial link between radioactive exposure and the diseases observed. Taking into account the importance of the problem, we started this study with the aim of establishing an effective and useful therapeutic program and assessing its efficacy during a one-year period of treatment. Chernobyl liquidators (n = 20) were screened by clinical history, physical examination, lung function test, chest radiograph, electrocardiogram, complete blood cell counts, serum chemistry, immunological blood tests, and complete BAL fluid investigation. One group of the patients (n = 10) underwent a special one-year treatment including polyvitamins, N-acetylcysteine, and therapeutic BAL every 3 months. The technique of therapeutic BAL has proven to be a promising and effective tool in the treatment of lung diseases induced by inhalation of radioactive particles.