[Dynamics of characteristics of the immune, cardiovascular, and autonomic nervous systems during aerocryotherapy in patients with different "immune health" status].

This study has demonstrated that subjects of different "immune health" status also differ in the activity of the vegetative nervous system. Aerocryotherapy was shown to have stimulatory effect on the immune system and decreased the hyperactivity of the parasympathetic nervous system especially in people suffering immune insufficiency.

[The effect of the physical status of the neutrophil membranes on their functional metabolic activity in hypertension patients]. / Vliianie fizicheskogo sostoianiia membran neitrofilov na ikh funktsional'no-metabolicheskuiu aktivnost' u bol'nykh gipertonicheskoi bolezn'iu.

In 76 untreated patients with Stages I-II hypertensive disease, spectrophotometry with lipid specific pyrene fluorescence probe revealed higher microviscosity in the lipid phase of neutrophilic membranes, which was induced by elevated levels of cholesterol and enhanced activation of lipid peroxidation. This resulted in increased functional and metabolic neutrophilic activity which was determined by luminol-dependent zimozan-induced chemiluminescence of whole venous blood. The correlation coefficient between the microviscosity of membranes and the chemiluminescence of neutrophils is 0.82 (p).

[Clinico-pathogenetic substantiation of comprehensive therapy of Klebsiella infection with the syndrome of water diarrhea in infants]. / Kliniko-patogeneticheskoe obosnovanie kompleksnoi terapii pri klebsielleznoi infektsii s sindromom "vodianistoi" diarei u detei rannego vozrasta.

The data on the examination of 70 infants with Klebsiella infection are presented. The patho-chemical disorders in the intestine under the action of Klebsiella were followed up in the time course and the adequacy of the pathogenetic therapy of the antiinflammatory and membrane protective destination was substantiated. The efficacies of the comprehensive therapy with the use of indomethacin, essential and dimephosphone and the therapy with antibacterial drugs such as monomycin, kanamycin, polymyxin and gentamicin administered orally were compared. The laboratory investigations, pharmaco-immunologic tests and clinical time course observations demonstrated the preference of the pathogenetic therapy of the patients with Klebsiella infection at the early stages of the watery diarrhea syndrome, when the functional disorders at the cellular level prevailed over the structural-and-morphological ones. In cases with complications the combined use of the pathogenetic and antibacterial drugs was more efficient.

[Immunity in patients with new onset infiltrative pulmonary tuberculosis who suffer from frequent respiratory viral infection]. / Immunnyi status bol'nykh s vpervye vyiavlennym infil'trativnym tuberkulezom legkikh, stradaiushchikh chastoi respiratornoi virusnoi infektsiei.

The rate of respiratory viral infection in the history affects the pattern of manifestations of pulmonary tuberculosis. With the manifestation of tuberculous infection, there is a reduction in the level of mature T lymphocytes and an increase in the values of monocytic oxygen-dependent metabolism (spontaneous and stimulated HCT test). Reductions in the level of activated proliferative cell markers of the lymphocytic link (CD38+ cells, expression of receptors for IL-2, Class II HLA antigens, and receptors for transferrin), in the absolute count of B lymphocytes, in the level of EA-POM and EA-phagocytosis of monocytes and an increase in the concentration of IgM occur more than 3 times a year in patients with respiratory viral infections.

[The peculiaries of the nutrition and immune status of people in the condition of penitentiary establishment]. / Osobennosti pishchevogo i immunnogo statusa lits, soderzhashchikhsia v usloviiakh penitentsiarnogo uchrezhdeniia.

The decrease of calorie in ration content, insufficient consumption of proteins and lipids was found among the patients in the condition of penitentiary establishment, it results in decrease of characteristics of natural immunity and resistibility to various infections agents, to the action of toxic substances, stress and other negative conditions that take place in penitentiary establishment a disbalanse of regulatory subpopulation of cellular consistent of immunity and predominance of suppressive-cytotoxic influence was observed among the patients of the penitentiary establishment (with a reduced ration of nutrition) over halt a year. Considering a health problem, in the establishments of imprisonment one may probably state that a reduced ration of nutrition is one of the main courses of immune homeostasis shift leasing in the basis of specific and non-specific phenomena of morbidity.