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1.
Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design.
Biochem Biophys Res Commun
; 2020 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32085900
2.
Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy.
Med Res Rev
; 39(4): 1398-1426, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30746734
3.
Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy.
Mol Pharmacol
; 96(1): 73-89, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31043459
4.
Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy.
Molecules
; 22(8)2017 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28763044
5.
X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor.
J Med Chem
; 64(17): 13072-13095, 2021 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34406768
6.
X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors.
ACS Chem Biol
; 14(12): 2810-2821, 2019 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31714738
7.
Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J Med Chem
; 62(14): 6734-6750, 2019 07 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31251599
8.
Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
J Med Chem
; 61(17): 7877-7891, 2018 09 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30122035
9.
A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Cancer Res
; 78(1): 265-277, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29180476
10.
Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors.
Eur J Med Chem
; 149: 211-224, 2018 Apr 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29501942
11.
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J Med Chem
; 61(4): 1704-1718, 2018 02 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29406710
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