Detalles de la búsqueda
1.
Revisiting a receptor-based pharmacophore hypothesis for human A(2A) adenosine receptor antagonists.
J Chem Inf Model
; 53(7): 1620-37, 2013 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23705857
2.
Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-ß1 expression in mesangial cells: biochemical and structural considerations.
Glycobiology
; 21(8): 1029-37, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21493663
3.
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites.
Bioorg Med Chem
; 17(14): 5259-74, 2009 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19501513
4.
Prediction of the aqueous solvation free energy of organic compounds by using autocorrelation of molecular electrostatic potential surface properties combined with response surface analysis.
Bioorg Med Chem
; 16(10): 5733-42, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18406153
5.
Ligand-based homology modeling as attractive tool to inspect GPCR structural plasticity.
Curr Pharm Des
; 12(17): 2175-85, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16796562
6.
Ligand-based drug design methodologies in drug discovery process: an overview.
Curr Drug Discov Technol
; 3(3): 155-65, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17311561
7.
Autocorrelation of molecular electrostatic potential surface properties combined with partial least squares analysis as new strategy for the prediction of the activity of human A(3) adenosine receptor antagonists.
J Med Chem
; 48(18): 5698-704, 2005 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-16134938
8.
A2B adenosine receptor antagonists: recent developments.
Mini Rev Med Chem
; 5(12): 1053-60, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16375751
9.
Autocorrelation of molecular electrostatic potential surface properties combined with partial least squares analysis as alternative attractive tool to generate ligand-based 3D-QSARs.
Curr Drug Discov Technol
; 2(1): 13-21, 2005 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16472237
10.
A Novel Generalized 3D-QSAR Model of Camptothecin Analogs.
Mol Inform
; 30(11-12): 927-38, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27468148
11.
Linear and nonlinear 3D-QSAR approaches in tandem with ligand-based homology modeling as a computational strategy to depict the pyrazolo-triazolo-pyrimidine antagonists binding site of the human adenosine A2A receptor.
J Chem Inf Model
; 48(2): 350-63, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18215030
12.
Combining ligand-based and structure-based drug design in the virtual screening arena.
Expert Opin Drug Discov
; 2(1): 37-49, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23496036
13.
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure-activity profile.
Purinergic Signal
; 3(3): 183-93, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18404432
14.
The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: application to a lead optimization of a human A3 adenosine receptor antagonist.
Bioorg Med Chem
; 14(14): 4923-32, 2006 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16564691
Resultados
1 -
14
de 14
1
Próxima >
>>