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1.
J Adolesc ; 96(2): 251-265, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-37985148

RESUMEN

INTRODUCTION: At-risk youth are those who are currently or potentially exposed to physical, mental, or emotional danger. The Friendship Online Intervention Program (FOIP) was created to encourage physical activity (PA) and reduce risky behavior among vocational secondary-school youth in Israel. We wanted to evaluate the effect of FOIP on PA, substance abuse, and psychological factors, including psychosomatic symptoms and well-being. METHODS: From October 2021 to June 2022, nonrandom sampling was employed to select at-risk youth from vocational secondary schools for participation in the FOIP. Before and after the intervention, questionnaires were administered to the intervention and control groups. The effects of FOIP were evaluated by univariate and multivariable analyses. RESULTS: The intervention (n = 103) and control (n = 77) groups showed similar levels of PA, cigarette smoking, and alcohol consumption at the beginning of the study. At follow-up, the intervention group showed a 57% increase in PA versus no change for the control group and decreased levels of smoking compared to the control group (p < .001). Similarly, in the intervention group, the number of psychosomatic symptoms decreased (effect size = 1.68) and life satisfaction increased (effect size = 0.86). Group assignment (intervention or control group) significantly predicted PA level, cigarette smoking, psychosomatic symptoms, and life satisfaction (adjusted R2 = .46, .20, .08, and .28, respectively) with participants in the intervention group showing more favorable results compared with the control group. CONCLUSIONS: FOIP was effective in increasing PA and decreasing risky behaviors among youth. FOIP may help at-risk youth build resilience and promote their physical and mental health.


Asunto(s)
Intervención basada en la Internet , Trastornos Relacionados con Sustancias , Humanos , Adolescente , Amigos , Ejercicio Físico/psicología , Trastornos Relacionados con Sustancias/prevención & control , Trastornos Relacionados con Sustancias/psicología , Trastornos Psicofisiológicos/psicología
2.
Harefuah ; 163(9): 571-578, 2024 Sep.
Artículo en Hebreo | MEDLINE | ID: mdl-39285596

RESUMEN

INTRODUCTION: Functional neurological disorder (FND) and complex regional pain syndrome (CRPS) are disorders that affect quality of life. CRPS diagnosis is based on Budapest criteria that include various signs/symptoms. Despite the similarity in the etiology/pathophysiology of FND and CRPS, the joint prevalence of these two conditions in youth has not yet been reported. Given that both phenomena are less familiar among pediatric patients, it is crucial to thoroughly characterize them and establish a clear differential diagnosis. This, in turn, holds significant implications for guiding therapeutic interventions. OBJECTIVES: We aimed to examine: 1) the clinical profile of children with FND; 2) the prevalence of CRPS among children with FND; and 3) differences in clinical characteristics and in Budapest's symptoms/signs between children with FND and those with a co-diagnosis of FND and CRPS. METHODS: Sixty-one children (mean age: 13.70+2.93 years; 75.4% females) diagnosed with FND were studied. Sample's demographic, clinical characteristics and the Budapest CRPS classification criteria were collected from medical files. RESULTS: Most children with FND reported sensory (67%) and motor (88%) symptoms. Forty-four percent had a co-diagnosis of FND and CRPS. Among these children, 100% reported sensory and motor/tropical, 74% vasomotor, and 65% sudomotor symptoms. The prevalence of Budapest symptoms, except for motor-function impairment, was significantly higher among children with a co-diagnosis compared to children with FND alone. CONCLUSIONS: The high frequency of symptoms and clinical signs in children with co-incidence of CRPS and FND may indicate a shared developmental mechanism and is important for the development of appropriate rehabilitation interventions.


Asunto(s)
Síndromes de Dolor Regional Complejo , Enfermedades del Sistema Nervioso , Humanos , Síndromes de Dolor Regional Complejo/epidemiología , Síndromes de Dolor Regional Complejo/diagnóstico , Síndromes de Dolor Regional Complejo/fisiopatología , Femenino , Adolescente , Niño , Masculino , Prevalencia , Enfermedades del Sistema Nervioso/epidemiología , Enfermedades del Sistema Nervioso/diagnóstico , Diagnóstico Diferencial , Calidad de Vida , Hungría/epidemiología
3.
BMC Public Health ; 23(1): 896, 2023 05 16.
Artículo en Inglés | MEDLINE | ID: mdl-37189074

RESUMEN

BACKGROUND: Cardiovascular diseases (CVD) are a precursor for disabilities and death worldwide. Being overweight or obese in combination with physical inactivity and smoking habits may increase the risk for CVD and other health problems such as lower limb osteoarthritis, diabetes, stroke, and various cancer types among children and adolescents. The literature emphasizes the need to follow such groups and evaluate the risk of individuals developing CVD diseases. Therefore, the current study explores the variety of cardiovascular risks in children and adolescents' profiles clusters with and without disabilities. METHODS: Data from 42 countries including Israel, was collected with the support of the world health organization (WHO, Europe) through a questionnaire from 11-19 years old school-aged. RESULTS: The study finding shows that children and adolescents with disabilities demonstrated a higher prevalence of overweight than those who completed the HBSC youth behavior survey. Moreover, the prevalence of tobacco smoking and alcohol use was statisticaly significantly higher among the disabled group than the non-disabled group. In addition, socioeconomic status of responders who presented a very high CVD risk was found as significantly lower than those from the first and second low risk groups. CONCLUSION: This led to the conclusion that children and adolescents with disability were at a higher risk of developing CVDs than their non-disabled peers. In addition, intervention programs tailored to the needs of adolescents with disability should consider lifestyle habit change and promoting healthy living thus improving their quality of life as well as reducing their risk of being exposed to severe CVD diseases.


Asunto(s)
Enfermedades Cardiovasculares , Personas con Discapacidad , Humanos , Adolescente , Niño , Adulto Joven , Adulto , Enfermedades Cardiovasculares/epidemiología , Sobrepeso/epidemiología , Calidad de Vida , Factores de Riesgo , Factores de Riesgo de Enfermedad Cardiaca
4.
Child Care Health Dev ; 49(3): 518-528, 2023 05.
Artículo en Inglés | MEDLINE | ID: mdl-36207992

RESUMEN

BACKGROUND: Parents report both positive and negative experiences associated with raising a child with a physical disability. However, distinctive factors may affect children and families differently. AIMS: Using a biopsychosocial approach, the current study expands on the existing literature on the general impact of raising a child with a disability. METHODS: Participants were 98 parents of children/youth with a physical disability. Parents reported on child's level of physical disability, the impact of the disability on the family (financial, social, personal strain and mastery) and their general health. Data were analysed to examine how different biopsychosocial factors are associated with raising a child with a physical disability. RESULTS: Parents reported that child's disability had a higher social impact, compared with the financial and personal burden, as well as compared with their sense of competency and mastery. Child's level of disability was associated with financial burden, whereas parental emotional distress was associated with parents' personal and social burden, with the latter also associated with parent's religiosity. Total impact was associated with parental emotional distress and educational level. CONCLUSIONS: Altogether, parental characteristics, but not child's characteristics, were associated with greater caregiver burden. Furthermore, the social impact a child's physical disability has on the family exceeded other sources of burden within the family. Providing parents social and emotional support, tailored to their unique biopsychosocial needs, may mitigate burden and distress, and increase sense of competency among families of children with a physical disability.


Asunto(s)
Crianza del Niño , Niños con Discapacidad , Padres , Adolescente , Humanos , Padres/psicología
5.
J Appl Res Intellect Disabil ; 36(5): 1113-1123, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37357316

RESUMEN

BACKGROUND: While people with intellectual disabilities tend to refrain from physical activity, outdoor physical activity programs increase motivation to engage in physical activity. METHOD: Eighty adults with intellectual disabilities participated in a 12-month outdoor physical activity program. Attendance was used to assess feasibility. Aerobic capacity (6-min walk test), lower extremity endurance (30-s chair stand), and mobility (timed up and go) were assessed at three-time points: before, during, and after the program. Six interviews were also conducted with six staff members and participants. RESULTS: The physical activity program was feasible, with all six groups completing the year-long activity. The six-minute walk and timed-up-and-go tests improved significantly. The qualitative analysis indicates the program's strengths (instructors' qualities and programs' social component) and weaknesses (dependency on weather and bureaucracy). CONCLUSION: Among adults with intellectual disabilities, a long-term outdoor physical activity program is feasible as a means for increasing aerobic capacity and improving mobility ability.


Asunto(s)
Discapacidad Intelectual , Humanos , Adulto , Estudios de Factibilidad , Ejercicio Físico , Caminata
6.
Adapt Phys Activ Q ; 40(3): 513-522, 2023 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-36577424

RESUMEN

Children and adolescents with disabilities (CAWD) represent 11% of Israeli children and adolescents. The 10 core indicators of the Global Matrix on Para Report Cards of physical activity (PA) of CAWD were used to create the 2022 Israeli Para Report Card. A panel of four experts reviewed resources and synthesized evidence of PA behaviors and policies for CAWD in Israel, converted the data to grades, and charted subcategories of language, sex, and disability across population. Data sources were surveys, reports, and memberships in sport federations and clubs. Among CAWD, levels of participation in daily PA were poor (<20%; Grade F), and participation of CAWD in sports was even lower (<10%; Grade F). A lack of environmental infrastructure may explain the low levels of participation. Females, Arabic speakers, and physiological CAWD need particular attention. Establishing governmental policies and interventions is required to increase overall PA and participation in sports among CAWD.


Asunto(s)
Niños con Discapacidad , Promoción de la Salud , Femenino , Humanos , Niño , Adolescente , Israel , Política de Salud , Juego e Implementos de Juego , Conducta Sedentaria , Ejercicio Físico
7.
Adapt Phys Activ Q ; 40(3): 431-455, 2023 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-36805931

RESUMEN

The purpose was to synthesize information gathered from the interpretation and conclusion sections of the Global Matrix of Para Report Cards on the physical activity of children and adolescents with disabilities. The synthesis was based on the strengths, weaknesses, opportunities, and threats framework. The procedure consisted of three stages: (a) the application of the International Classification of Functioning, Disability and Health as the theoretical framework; (b) identifying and aligning Global Matrix indicators and benchmarks with the International Classification of Functioning, Disability and Health components through a Delphi approach; and (c) using content analysis to identify themes from specific report cards. Outcomes reveal that further attention toward including children and adolescents with disabilities in fitness assessments is needed as well as adapted assessment methods. Program availability, equipment and facilities, and professional training emerged as strengths but need further development to overcome weaknesses. Paralympic inspiration was an opportunity, whereas extreme weather conditions presented potential threats to physical activity participation among children and adolescents with disabilities.


Asunto(s)
Personas con Discapacidad , Niño , Humanos , Adolescente , Ejercicio Físico
8.
Phys Occup Ther Pediatr ; 42(6): 579-594, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35440261

RESUMEN

AIMS: To characterize multidisciplinary healthcare resource utilization (mHRU), including physical, occupational, speech and psychosocial therapy one-year following discharge from prolonged inpatient and outpatient pediatric rehabilitation in Israel and to identify factors associated with long-term mHRU. METHODS: According to Andersen's model of health service use, predisposing (child's age and sex), enabling (district of origin, income level, parental education, insurance) and need factors (injury type, functional status, family psychosocial risk) were collected from parents of children hospitalized for >1 month in a large rehabilitation hospital in Israel, and phone interviews were held 3-months (T1), 6-months (T2) and 12-months (T3) post-discharge. The effect of time and the role of various factors on mHRU, operationalized as number of therapy sessions in the previous 2 weeks, were evaluated. RESULTS: Sixty-one families participated at T1 and T2, and 46 participated at T3. HRU was similar over time. Predisposing factors (age) and need factors (functional status and psychosocial risk) were associated with specific disciplines of mHRU, but enabling factors were not. CONCLUSIONS: mHRU is high and stable 12-months post-discharge. The lack of impact of enabling factors on mHRU, and the discipline-specific impact of predisposing and need factors, support equity of care provision for children following prolonged rehabilitation.


Asunto(s)
Cuidados Posteriores , Alta del Paciente , Niño , Estudios de Seguimiento , Humanos , Padres , Aceptación de la Atención de Salud
9.
BMC Public Health ; 21(1): 1521, 2021 08 06.
Artículo en Inglés | MEDLINE | ID: mdl-34362319

RESUMEN

BACKGROUND: The COVID-19 outbreak holds public health concerns. The stay-at-home increases sedentary behavior, with unintended adverse outcomes. Since organized recreation and sports facilities were closed, we aimed to study how the crisis of closure affected exercise habits and weight gain among the trainee population in Israel. We examined differences in weight gain among individuals with different PA activities and assessed their ability to adapt to digital media as an alternative training structure. METHODS: A cross-sectional survey consisted of a multiple-choice questionnaire obtained using a web-based survey application. Trainees (1202) who exercised steadily anonymously answered the questionnaire sent by their coaches regarding their activity and weight gain during lockdown times. RESULTS: Results confirmed that 70% of Israelis trained less than their usual routine, 60% used digital media for training, 55% gained weight. Half of the respondents gained more than 2 kg, with an average increase of 1.2 kg. However, those who exhibited a higher physical activity level gained less weight. Using digital media for training was associated with higher physical activity levels. The aged population was less likely to use digital media. CONCLUSIONS: Since increased sedentary behavior could increase the risk for potential worsening of health conditions, health agencies should look for strategies, including digital remote media training to promote physical activity and subsequently, preventing the increased burden of future comorbidities worsening by a sedentary lifestyle. Approval: by the Helsinki ethics committee of Sheba Medical Center (6504-19-SMC).


Asunto(s)
COVID-19 , Adulto , Anciano , Control de Enfermedades Transmisibles , Estudios Transversales , Ejercicio Físico , Humanos , Internet , Israel/epidemiología , SARS-CoV-2 , Aumento de Peso
10.
J Appl Res Intellect Disabil ; 32(6): 1401-1411, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31124217

RESUMEN

BACKGROUND: Soccer is the world's most popular sport. The present authors evaluated the effect of the Game of Life (GOL) soccer initiative on soccer skills, fitness and mobility of adults with intellectual disability (ID) and autism spectrum disorder (ASD). METHODS: The programme is comprised of once-weekly sessions. OUTCOMES: soccer skills, fitness and mobility. Effectiveness was evaluated using within-/between-group analyses (e.g. effect size, ES). RESULTS: Fifty adults with intellectual disability and 19 with ASD (age = 31.80 ± 10.11) participated in this study. From pre-test to post-test, the intellectual disability group improved their soccer skills (ES = 0.437); physical fitness-the intellectual disability group presented trivial ESs, whereas the ASD group showed moderate-to-large ESs; Mobility-only the ASD group presented a significant improvement (ES=-0.435), and the intellectual disability group presented better ability in most outcomes in pre- and post-tests. CONCLUSION: The findings indicated differences in entry-level performance and training impact between the two groups. This should be considered when developing training programmes for soccer players.


Asunto(s)
Rendimiento Atlético , Trastorno del Espectro Autista , Discapacidad Intelectual , Aptitud Física , Fútbol , Deportes para Personas con Discapacidad , Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
11.
Harefuah ; 157(8): 511-516, 2018 Aug.
Artículo en Hebreo | MEDLINE | ID: mdl-30175567

RESUMEN

INTRODUCTION: Lower limb deficiency in childhood has an impact on acquisition of motor skills. Information regarding the characteristics of this population was examined in several countries but not in Israel. AIMS: To provide demographics, clinical and functional characteristics of children with lower limb deficiency in a pediatric rehabilitation department. METHODS: Children with lower limb deficiency participated in this study. The study variables included demographics, and clinical and functional characteristics. The statistical analysis included calculations of frequency, chi-squared tests and correlations. RESULTS: During the years 1998-2015 fifty-eight children with lower extremity deformity were treated/examined in the department (mean age: 6.46+4.70 years; girls, n=21; congenital deformity, n=23; acquired deformity, n=35). The most common congenital and acquired injury was unilateral leg deformity (31% and 35%, respectively). In congenital injury, multi-limb deformity (including an involvement in the upper limb) is more prevalent than bilateral lower limb deformity (p<0.01). In children with congenital deformity, longitudinal deformity is more prevalent than transverse deformity (p<0.03). Among children with acquired injury, in 40% the etiology was sickness-related and in the rest traumatic. Among the traumatic group, 57% of the injuries were terror-related. More than 50% percent of the children underwent a complex surgical procedure (34% and 22% among congenital and acquired injury, respectively). The ambulation level of the sample was lower than expected. CONCLUSIONS: Children who received treatment due to lower limb deformity presented high variability in their characteristics and low ambulation level. Consequently, it is important to create and manage a register for pediatric lower limb deformity.


Asunto(s)
Deformidades Congénitas de las Extremidades Inferiores , Deformidades Congénitas de las Extremidades Superiores , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Israel/epidemiología , Deformidades Congénitas de las Extremidades Inferiores/epidemiología , Deformidades Congénitas de las Extremidades Inferiores/terapia , Deformidades Congénitas de las Extremidades Superiores/epidemiología , Deformidades Congénitas de las Extremidades Superiores/terapia , Caminata
12.
Vascular ; 24(3): 304-14, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-26209234

RESUMEN

Intermittent claudication, a common symptom of peripheral arterial disease, results in insufficient blood flow and oxygen supply to lower extremity muscles. Compared to men, women with peripheral arterial disease have a higher rate of mobility loss with peripheral arterial disease due to poorer lower extremity functioning. This study evaluates the effect of supervised pain-free treadmill exercise on improving performance in women with intermittent claudication due to peripheral arterial disease in comparison to men. A total of 26 participants (women, n = 9, 34.62%; mean age = 67.58 ± 5.59 years; averaging 23.46 ± 3.91 visits and 10.46 ± 0.99 weeks in the program) diagnosed with peripheral arterial disease, with symptoms of intermittent claudication, partook in a 45 min treadmill walk, twice per week, below the participant's minimal pain threshold. Female participants' change scores showed 752%, 278% and 115% improvement in mean walking distance, duration and rate, respectively. Men improved 334%, 149% and 80%, respectively. Significant differences (p < 0.05) in pre and post measurements within each group support positive outcomes. No significant differences between groups were observed (Cohen's d effect size > 0.80). Our results suggest that women reap similar benefits from this low-intensity treadmill program in comparison to men.


Asunto(s)
Terapia por Ejercicio/métodos , Tolerancia al Ejercicio , Claudicación Intermitente/terapia , Enfermedad Arterial Periférica/terapia , Caminata , Anciano , Terapia por Ejercicio/efectos adversos , Femenino , Humanos , Claudicación Intermitente/diagnóstico , Claudicación Intermitente/fisiopatología , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Enfermedad Arterial Periférica/diagnóstico , Enfermedad Arterial Periférica/fisiopatología , Recuperación de la Función , Factores Sexuales , Encuestas y Cuestionarios , Factores de Tiempo , Resultado del Tratamiento
13.
Harefuah ; 155(6): 364-9, 385, 2016 Jun.
Artículo en Hebreo | MEDLINE | ID: mdl-27544990

RESUMEN

This review summarizes the existing knowledge regarding the effects and recommendations for physical training (PTr) in patients with multiple sclerosis (MS). In addition, perceived benefits and barriers to PTr in this population are reviewed. One of the primary aims of rehabilitation for patients with MS is to increase their levels of activity and independence. PTr is a central component in the rehabilitation process. Nonetheless, the use of PTr in the rehabilitation of patients with MS has been a controversial issue for years. Nowadays, strong evidence exists that aerobic training in individuals with MS has a positive effect on overall physical conditioning, gait speed, fatigue, depression and cognition. Unlike aerobic training, the number of studies that investigated strength training effects in this population is limited. However, the available data show that resistance training also has beneficial effects on MS patients. It is important to note, that PTr has no deleterious effects in MS patients. In the various studies, there was diversity with regard to the duration and the frequency of PTr, while intensity was often poorly described. It is recommended that individuals with MS engage in aerobic training (at 60-80% of maximal heart rate), strength training (1-3 sets of 8-15 repetitions), the range of motion, balance and ambulation exercises. Awareness of the benefits of physical activity and sense of achievement are not sufficient to promote exercise participation in persons with MS. Factors relating to physical exertion, sports facilities availability and self-efficacy play an important role in promoting exercise participation.


Asunto(s)
Terapia por Ejercicio , Esclerosis Múltiple , Calidad de Vida , Ensayos Clínicos como Asunto , Terapia por Ejercicio/clasificación , Terapia por Ejercicio/métodos , Tolerancia al Ejercicio/fisiología , Humanos , Vida Independiente , Esclerosis Múltiple/fisiopatología , Esclerosis Múltiple/psicología , Esclerosis Múltiple/rehabilitación
14.
Harefuah ; 155(6): 378-83, 384, 2016 Jun.
Artículo en Hebreo | MEDLINE | ID: mdl-27544993

RESUMEN

This review summarizes the knowledge regarding the effects and recommendations for physical training (PTr) post-stroke. In addition, perceived benefits/barriers to PTr post-stroke are reviewed. PTr is an important post-stroke rehabilitation goal. Before beginning a PTr program it is recommended to conduct a physical examination. There is evidence that aerobic training post-stroke has a positive effect on gait and on risk factors for recurrent stroke. Similarly, strength training is also safe and effective. However, this training modality does not improve.gait functions. Neuromuscular training post-stroke is also a recommended training method. In the various studies conducted, there was diversity with regard to duration and frequency of PTr. It is recommended that individuals post-stroke engage in aerobic training 3-5 days a week. During the acute phase, the rating of perceived exertion should be "fairly light" (less or equal to 11 on the Borg scale, which ranges 6-20). In more advanced phases of recovery, one ca exercise at a higher intensity of up to "somewhat hard" (rating of perceived exertion 11-14; 55-80% of maximal heart rate). It is also recommended to conduct strength training (2-3 days per week, 1-3 sets of 10-15 repetitions), and flexibility and neuromuscular training (2-3 days per week). In order to encourage individuals post-stroke to conduct PTr there is a need for social support (from caregivers and family) and to provide PTr consultation. PTr barriers consist of both personal (e.g., depression, knowledge regarding physical activity centers) and environmental (e.g., lack of transportation) factors.


Asunto(s)
Terapia por Ejercicio , Rehabilitación de Accidente Cerebrovascular , Terapia por Ejercicio/efectos adversos , Terapia por Ejercicio/métodos , Humanos , Medición de Riesgo/métodos , Prevención Secundaria/métodos
16.
Harefuah ; 153(5): 266-72, 305, 2014 May.
Artículo en Hebreo | MEDLINE | ID: mdl-25112118

RESUMEN

The management goal of cerebral palsy (CP) is improving functionality, locomotion and independence. Treatment programs commonly encompass adapted physical activity (APA). This review summarizes the knowledge regarding the effects and recommendations for APA in persons with CP. In addition, barriers to APA in this population are reviewed. The available literature on benefits of APA to persons with CP has focused mainly on youth. The components of the APA programs generally consist of strength, aerobic and flexibility training. There is no empirical evidence that strength-training increases spasticity in people with CP. Furthermore, strength-training may increase strength and the ability to perform daily activities. Aerobic-training is especially important as persons with CP typically have low cardiorespiratory fitness and high prevalence of cardiac disease. However, limited published evidence exists on aerobic-training effects in this population. Nonetheless, the evidence suggests that aerobic-training in persons with CP can improve physiological outcomes, yet the influence of these changes on participation has not been investigated sufficiently. Stretching exercise is a common treatment for spasticity. Surprisingly, there is inconclusive evidence for the effectiveness of stretching exercise for persons with CP. Despite the importance attributed to APA for people with CP, low levels of physical activity have been reported in this population. However, when caregivers perceive greater benefits of exercise, individuals with CP are more likely to be active. In contrast, barriers to APA include costs of APA programs, limited means of transportation to APA facilities, lack of information regarding APA facilities and limited appropriate exercising equipment in the APA facilities.


Asunto(s)
Parálisis Cerebral , Terapia por Ejercicio , Actividad Motora/fisiología , Espasticidad Muscular/rehabilitación , Actividades Cotidianas , Parálisis Cerebral/fisiopatología , Parálisis Cerebral/psicología , Parálisis Cerebral/rehabilitación , Terapia por Ejercicio/efectos adversos , Terapia por Ejercicio/economía , Terapia por Ejercicio/métodos , Accesibilidad a los Servicios de Salud/organización & administración , Humanos , Vida Independiente , Locomoción , Evaluación de Necesidades , Planificación de Atención al Paciente , Resistencia Física , Aptitud Física , Resultado del Tratamiento
17.
Healthcare (Basel) ; 12(2)2024 Jan 18.
Artículo en Inglés | MEDLINE | ID: mdl-38255134

RESUMEN

Individuals with autism spectrum disorder (ASD) are at higher risk for developing common chronic diseases. Engagement in physical activity (PA) can prevent health issues; however, people with ASD are known to engage in lower levels of PA in comparison to their peers. This study evaluated the effect of a long-term, 12-month PA intervention on the fitness and quality of life of adults with ASD. A quantitative approach was implemented to assess participants' fitness, functional ability, quality of life, and participation in a range of PA classes at three different time points. Qualitative data were collected via in-depth, semi-structured interviews with three participants with ASD and three staff members. A total of 34 adults with ASD (mean age 39.76 + 7.27) participated in the quantitative part of the study. Approximately 53% of the participants exhibited perseverance and conducted adequate PA each month. Significant improvements were found in one fitness component and two quality-of-life components. Factors revealed for the program's success were the individuals' free choice of the PA classes and supporting people and a budget that tailored the project. Policymakers who plan health promotion programs for adults with ASD should consider long-term PA programs, with freedom of choice among PA modalities and schedules.

18.
Mol Autism ; 15(1): 31, 2024 07 24.
Artículo en Inglés | MEDLINE | ID: mdl-39049050

RESUMEN

BACKGROUND: Angelman syndrome (AS) is a rare neurodevelopmental genetic disorder caused by the loss of function of the ubiquitin ligase E3A (UBE3A) gene, affecting approximately 1:15,000 live births. We have recently shown that mitochondrial function in AS is altered during mid to late embryonic brain development leading to increased oxidative stress and enhanced apoptosis of neural precursor cells. However, the overall alterations of metabolic processes are still unknown. Hence, as a follow-up, we aim to investigate the metabolic profiles of wild-type (WT) and AS littermates and to identify which metabolic processes are aberrant in the brain of AS model mice during embryonic development. METHODS: We collected brain tissue samples from mice embryos at E16.5 and performed metabolomic analyses using proton nuclear magnetic resonance (1H-NMR) spectroscopy. Multivariate and Univariate analyses were performed to determine the significantly altered metabolites in AS mice. Pathways associated with the altered metabolites were identified using metabolite set enrichment analysis. RESULTS: Our analysis showed that overall, the metabolomic fingerprint of AS embryonic brains differed from those of their WT littermates. Moreover, we revealed a significant elevation of distinct metabolites, such as acetate, lactate, and succinate in the AS samples compared to the WT samples. The elevated metabolites were significantly associated with the pyruvate metabolism and glycolytic pathways. LIMITATIONS: Only 14 metabolites were successfully identified and investigated in the present study. The effect of unidentified metabolites and their unresolved peaks was not determined. Additionally, we conducted the metabolomic study on whole brain tissue samples. Employing high-resolution NMR studies on different brain regions could further expand our knowledge regarding metabolic alterations in the AS brain. Furthermore, increasing the sample size could reveal the involvement of more significantly altered metabolites in the pathophysiology of the AS brain. CONCLUSIONS: Ube3a loss of function alters bioenergy-related metabolism in the AS brain during embryonic development. Furthermore, these neurochemical changes could be linked to the mitochondrial reactive oxygen species and oxidative stress that occurs during the AS embryonic development.


Asunto(s)
Síndrome de Angelman , Encéfalo , Modelos Animales de Enfermedad , Metabolómica , Espectroscopía de Protones por Resonancia Magnética , Animales , Síndrome de Angelman/metabolismo , Síndrome de Angelman/genética , Encéfalo/metabolismo , Encéfalo/diagnóstico por imagen , Ratones , Metaboloma , Ubiquitina-Proteína Ligasas/metabolismo , Ubiquitina-Proteína Ligasas/genética , Femenino
19.
Front Sports Act Living ; 6: 1284421, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38318486

RESUMEN

Introduction: Acquired brain injury (ABI) is a prevalent diagnosis in pediatric rehabilitation. Gross motor skills are often affected by ABI and limit the ability to participate in various physical activities. However, as ABI injury location is diverse, children and adolescents (youth) with localized ABI, such as ABI in the posterior fossa (ABI-PF) may present unique and different motor disabilities than youth with ABI on account of traumatic brain injury (TBI). Aims: The aims of the study were: (1) to compare gross motor deficits in youth with TBI vs. ABI-PF; and (2) to compare two methods on scoring BOT2 to determine which is better for identifying motor deficits. Methods: Participated in this study youth with TBI (N = 50) and ABI-PF (N = 30). Participants were tested on Bruininks-Oseretsky Test of Motor Proficiency-2nd Edition (BOT2) Upper-Limb Coordination, Balance, Strength, Running Speed and Agility, and Bilateral-Coordination subtests. Motor performance deficits were established using two-standard deviations (2SD) and age-equivalent methods. Between-group differences were assessed via independent t-tests and receiver operating characteristic curves (ROC). Results: According to the 2SD method, motor deficits in the ABI-PF group ranged from 20% to 66.66%, whereas in the TBI group 8%-16%. According to the age-equivalent method, in the TBI and ABI-PF groups 40%-66.0% and 46.66%-76.66% of the youth presented motor deficits, respectively. Moreover, ROC analysis showed that motor performance deficits of both groups in all sub-scales except for Bilateral Coordination differed enough to result in medium area under the curve. Conclusions: Motor deficits post-pediatric ABI are prevalent. In comparison to the TBI group, deficits are greater in the ABI-PF group. Moreover, compared to the 2SD method, the extent of motor deficiency is greater in the age-equivalent method. Therefore, using the later might provide a more valid classification of deficits in gross motor proficiency for youth post-ABI.

20.
Sports Med ; 2024 Oct 03.
Artículo en Inglés | MEDLINE | ID: mdl-39361231

RESUMEN

BACKGROUND: The actions required to achieve higher-quality and harmonised global surveillance of child and adolescent movement behaviours (physical activity, sedentary behaviour including screen time, sleep) are unclear. OBJECTIVE: To identify how to improve surveillance of movement behaviours, from the perspective of experts. METHODS: This Delphi Study involved 62 experts from the SUNRISE International Study of Movement Behaviours in the Early Years and Active Healthy Kids Global Alliance (AHKGA). Two survey rounds were used, with items categorised under: (1) funding, (2) capacity building, (3) methods, and (4) other issues (e.g., policymaker awareness of relevant WHO Guidelines and Strategies). Expert participants ranked 40 items on a five-point Likert scale from 'extremely' to 'not at all' important. Consensus was defined as > 70% rating of 'extremely' or 'very' important. RESULTS: We received 62 responses to round 1 of the survey and 59 to round 2. There was consensus for most items. The two highest rated round 2 items in each category were the following; for funding (1) it was greater funding for surveillance and public funding of surveillance; for capacity building (2) it was increased human capacity for surveillance (e.g. knowledge, skills) and regional or global partnerships to support national surveillance; for methods (3) it was standard protocols for surveillance measures and improved measurement method for screen time; and for other issues (4) it was greater awareness of physical activity guidelines and strategies from WHO and greater awareness of the importance of surveillance for NCD prevention. We generally found no significant differences in priorities between low-middle-income (n = 29) and high-income countries (n = 30) or between SUNRISE (n = 20), AHKGA (n = 26) or both (n = 13) initiatives. There was a lack of agreement on using private funding for surveillance or surveillance research. CONCLUSIONS: This study provides a prioritised and international consensus list of actions required to improve surveillance of movement behaviours in children and adolescents globally.

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