RESUMEN
OBJECTIVE: To evaluate the efficacy of a three-dimensional (3D)-printed, patient-specific reduction system for aligning diaphyseal tibial fractures stabilized using minimally invasive plate osteosynthesis (MIPO). STUDY DESIGN: Prospective clinical trial. SAMPLE POPULATION: Fifteen client owned dogs. METHODS: Virtual 3D models of both pelvic limbs were created. Pin guides were designed to conform to the proximal and distal tibia. A reduction bridge was designed to align the pin guides based on the guides' spatial location. Guides were 3D printed, sterilized, and applied, in conjunction with transient application of a circular fixator, to facilitate indirect fracture realignment before plate application. Alignment of the stabilized tibiae was assessed using postoperative computed tomography scans. RESULTS: Mean duration required for virtual planning was 2.5 h and a mean of 50.7 h elapsed between presentation and surgery. Guide placement was accurate with minor median discrepancies in translation and frontal, sagittal, and axial plane positioning of 2.9 mm, 3.6°, 2.7°, and 6.8°, respectively. Application of the reduction system restored mean tibial length and frontal, sagittal, and axial alignment within 1.7 mm, 1.9°, 1.7°, and 4.5°, respectively, of the contralateral tibia. CONCLUSION: Design and fabrication of a 3D-printed, patient-specific fracture reduction system is feasible in a relevant clinical timeline. Intraoperative pin-guide placement was reasonably accurate with minor discrepancies compared to the virtual plan. Custom 3D-printed reduction system application facilitated near-anatomic or acceptable fracture reduction in all dogs. CLINICAL SIGNIFICANCE: Virtual planning and fabrication of a 3D-printing patient-specific fracture reduction system is practical and facilitated acceptable, if not near-anatomic, fracture alignment during MIPO.
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Placas Óseas , Fijación Interna de Fracturas , Impresión Tridimensional , Fracturas de la Tibia , Animales , Perros/lesiones , Perros/cirugía , Fracturas de la Tibia/cirugía , Fracturas de la Tibia/veterinaria , Fijación Interna de Fracturas/veterinaria , Fijación Interna de Fracturas/métodos , Fijación Interna de Fracturas/instrumentación , Placas Óseas/veterinaria , Estudios Prospectivos , Masculino , Femenino , Procedimientos Quirúrgicos Mínimamente Invasivos/veterinaria , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/instrumentaciónRESUMEN
OBJECTIVE: To compare the efficacy and clinical outcomes of computed tomography (CT)-based virtual surgical planning (VSP) and a three-dimensional (3D)-printed, patient-specific reduction system to conventional indirect reduction techniques for diaphyseal tibial fractures stabilized using minimally invasive plate osteosynthesis (MIPO) in dogs. STUDY DESIGN: A prospective clinical study with a historic control cohort. SAMPLE POPULATION: Dogs undergoing MIPO stabilization of diaphyseal tibial fractures using a custom 3D-printed reduction system (3D-MIPO; n = 15) or conventional indirect reduction techniques (c-MIPO; n = 14). METHODS: Dogs were prospectively enrolled to the 3D-MIPO group and CT scans were used to design and fabricate a custom 3D-printed reduction system to facilitate MIPO. Medical records were searched to identify dogs for the c-MIPO group. Pre-, intra- and postoperative parameters were compared between groups. RESULTS: The duration from presentation until surgery was 23 h longer in the 3D-MIPO group (p = .002). Fewer intraoperative fluoroscopic images were acquired (p < .001) and mean surgical duration was 34 min shorter in the 3D-MIPO group (p = .014). Median postoperative tibial length, frontal alignment, and sagittal alignment were within 4 mm, 3° and 3°, respectively, of the contralateral tibia in both groups and did not differ between reduction groups (p > .1). Postoperative complications occurred in 27% and 14% of fractures in the 3D-MIPO and c-MIPO groups, respectively. CONCLUSION: Both reduction methods yielded comparable results. Although the preoperative planning and guide preparation was time consuming, surgery times were shorter and fluoroscopy use was less in the 3D-MIPO group. CLINICAL SIGNIFICANCE: VSP and the custom 3D-printed reduction system facilitated efficient MIPO.
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Placas Óseas , Fijación Interna de Fracturas , Impresión Tridimensional , Fracturas de la Tibia , Animales , Perros/cirugía , Perros/lesiones , Fijación Interna de Fracturas/veterinaria , Fijación Interna de Fracturas/métodos , Fijación Interna de Fracturas/instrumentación , Fracturas de la Tibia/cirugía , Fracturas de la Tibia/veterinaria , Fracturas de la Tibia/diagnóstico por imagen , Placas Óseas/veterinaria , Masculino , Femenino , Estudios de Casos y Controles , Estudios Prospectivos , Tomografía Computarizada por Rayos X/veterinaria , Procedimientos Quirúrgicos Mínimamente Invasivos/veterinaria , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Enfermedades de los Perros/cirugía , Cirugía Asistida por Computador/veterinaria , Cirugía Asistida por Computador/métodosRESUMEN
OBJECTIVE: To describe and evaluate minimally invasive repair of acetabular fractures in dogs using plates contoured to 3D-printed hemipelvic models. STUDY DESIGN: Ex vivo feasibility study and case report. SAMPLE POPULATION: Adult canine cadavers (n = 5); 8 year old male neutered Chihuahua. METHODS: Bone plates were contoured to 3D printed hemipelvic models derived from computed tomographic scans of each dog. In cadavers, acetabular, ischial, and pubic osteotomies were performed. A small craniolateral approach to the ilial body and a caudal approach to the ischium were made and connected through epiperiosteal tunnels. Under fluoroscopic guidance, fractures were reduced, and precontoured bone plates were applied with locking screws. Postoperative computed tomographic images were used to assess fracture gaps, step defects, and pelvic angulation. Cadavers were dissected for subjective assessment of sciatic nerve injury. Radiographic and clinical follow up was acquired for the clinical case. RESULTS: Small fracture gaps (<2 mm) and step defects (<1 mm), low pelvic angulation (<5°), and minimal (none n = 4 and mild n = 1) sciatic nerve injuries were observed in cadaver testing. There was slight (~1 mm) medial displacement of the pubic segment and good functional outcome for the clinical case, with radiographic healing documented at 3 months postoperatively. CONCLUSION: Minimally invasive acetabular fracture repair in dogs with the aid of 3D printing was feasible and accurate. CLINICAL SIGNIFICANCE: Minimally invasive repair techniques assisted by 3D printing may be applicable for acetabular fractures in dogs. The technique should be evaluated further before routine use can be recommended.
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Enfermedades de los Perros , Fracturas Óseas , Fracturas de la Columna Vertebral , Masculino , Perros , Animales , Fijación Interna de Fracturas/veterinaria , Fijación Interna de Fracturas/métodos , Estudios de Factibilidad , Tornillos Óseos , Fracturas Óseas/cirugía , Fracturas Óseas/veterinaria , Fracturas de la Columna Vertebral/veterinaria , Acetábulo/cirugía , Placas Óseas , CadáverRESUMEN
OBJECTIVE: Assess the accuracy and efficiency of reduction provided by application of plates precontoured to 3-dimensional (3D)-printed femoral bone models using a custom fracture reduction system (FRS) or intramedullary pin (IMP) to facilitate femoral minimally invasive plate osteosynthesis (MIPO) in dogs. STUDY DESIGN: Experimental cadaveric study. SAMPLE POPULATION: Seven dog cadavers. METHODS: Virtual 3D femoral models were created using computed tomographic images. Simulated, virtual mid-diaphyseal femoral fractures were created and reduced. Reduced femoral models were 3D-printed and a plate was contoured. Custom drill guides for plate screw placement were designed and 3D-printed for the FRS. Mid-diaphyseal simulated comminuted fractures were created in cadavers, and fractures were aligned using FRS or IMP and stabilized with the precontoured plates. Number of fluoroscopic images acquired per procedure and surgical duration were recorded. Computed tomographic scans were repeated to assess femoral length and alignment. RESULTS: Compared to the preoperative virtual plan, median change in femoral length and frontal, sagittal, and axial alignment was less than 3 mm, 2°, 3°, and 3° postoperatively, respectively, in both reduction groups. There was no difference in length or alignment between reduction groups (P > .05). During FRS, fewer fluoroscopic images were taken (P = .001), however, surgical duration was longer than IMP procedures (P = .011). CONCLUSION: Femoral alignment was accurate when using plates precontoured to 3D printed models, regardless of reduction method. CLINICAL SIGNIFICANCE: Accurate plate contouring using anatomically accurate models may improve fracture reduction accuracy during MIPO applications. Custom surgical guides may reduce fluoroscopy use associated with MIPO.
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Enfermedades de los Perros , Fracturas del Fémur , Perros , Animales , Procedimientos Quirúrgicos Mínimamente Invasivos/veterinaria , Fracturas del Fémur/diagnóstico por imagen , Fracturas del Fémur/cirugía , Fracturas del Fémur/veterinaria , Fijación Interna de Fracturas/veterinaria , Fijación Interna de Fracturas/métodos , Placas Óseas/veterinaria , Cadáver , Impresión Tridimensional , Enfermedades de los Perros/cirugíaRESUMEN
OBJECTIVE: To evaluate the impact of a 30% end-inspiratory pause (EIP) on alveolar tidal volume (VTalv), airway (VDaw) and physiological (VDphys) dead spaces in mechanically ventilated horses using volumetric capnography, and to evaluate the effect of EIP on carbon dioxide (CO2) elimination per breath (Vco2br-1), PaCO2, and the ratio of PaO2-to-fractional inspired oxygen (PaO2:FiO2). STUDY DESIGN: Prospective research study. ANIMALS: A group of eight healthy research horses undergoing laparotomy. METHODS: Anesthetized horses were mechanically ventilated as follows: 6 breaths minute-1, tidal volume (VT) 13 mL kg-1, inspiratory-to-expiratory time ratio 1:2, positive end-expiratory pressure 5 cmH2O and EIP 0%. Vco2br-1 and expired tidal volume (VTE) of 10 consecutive breaths were recorded 30 minutes after induction, after adding 30% EIP and upon EIP removal to construct volumetric capnograms. A stabilization period of 15 minutes was allowed between phases. Data were analyzed using a mixed-effect linear model. Significance was set at p < 0.05. RESULTS: The EIP decreased VDaw from 6.6 (6.1-6.7) to 5.5 (5.3-6.1) mL kg-1 (p < 0.001) and increased VTalv from 7.7 ± 0.7 to 8.6 ± 0.6 mL kg-1 (p = 0.002) without changing the VTE. The VDphys to VTE ratio decreased from 51.0% to 45.5% (p < 0.001) with EIP. The EIP also increased PaO2:FiO2 from 393.3 ± 160.7 to 450.5 ± 182.5 mmHg (52.5 ± 21.4 to 60.0 ± 24.3 kPa; p < 0.001) and Vco2br-1 from 0.49 (0.45-0.50) to 0.59 (0.45-0.61) mL kg-1 (p = 0.008) without reducing PaCO2. CONCLUSIONS AND CLINICAL RELEVANCE: The EIP improved oxygenation and reduced VDaw and VDphys, without reductions in PaCO2. Future studies should evaluate the impact of different EIP in healthy and pathological equine populations under anesthesia.
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Pulmón , Respiración con Presión Positiva , Caballos/cirugía , Animales , Estudios Prospectivos , Respiración con Presión Positiva/veterinaria , Volumen de Ventilación Pulmonar/fisiología , Dióxido de Carbono , Respiración Artificial/veterinariaRESUMEN
OBJECTIVE: To evaluate the effectiveness of a novel crescent-shaped tibial plateau-leveling osteotomy (TPLO) saw guide (crescent guide) to assist with saw control in novice participants. STUDY DESIGN: Ex vivo study. SAMPLE POPULATION: Synthetic bones (n = 54) and medium sized dog pelvic limbs (n = 36). METHODS: The 6 participants (interns and residents) without any prior experience performing a TPLO each performed 9 osteotomies on synthetic tibia models, and 6 osteotomies in cadaveric limbs of medium-sized dogs. Osteotomies made with the crescent guide were compared with those made with a standard jig and a radial saw guide with a jig. Osteotomy angulation, distance of eccentricity (DOE), and medial tibial cortical damage (synthetic bone models only) were measured from calibrated photographs. Participants rated their experiences with each technique. RESULTS: There was no difference in the DOE, coronal or axial osteotomy angulation between the 3 alignment devices for synthetic bone models or cadavers. Average medial cortical damage with the crescent guide (3.8 ± 7.3 mm2 ) was lower than with the radial guide (35.7 ± 27 mm2 ) and standard jig (51.2 ± 63.2 mm2 ) guides (P = <.01). Five of 6 participants preferred the crescent guide over the standard jig and radial guide. CONCLUSION: There was no difference in accuracy of osteotomy positioning but using the crescent guide resulted in lower cortical damage and more favorable participant perceptions. CLINICAL RELEVANCE: The crescent guide may improve control of the radial saw during TPLO in novice surgeons but does not appear to aid accurate osteotomy positioning.
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Lesiones del Ligamento Cruzado Anterior , Enfermedades de los Perros , Osteotomía , Animales , Lesiones del Ligamento Cruzado Anterior/veterinaria , Cadáver , Enfermedades de los Perros/cirugía , Perros , Extremidades , Miembro Posterior , Humanos , Osteotomía/métodos , Osteotomía/veterinaria , Rodilla de Cuadrúpedos/cirugía , Tibia/cirugíaRESUMEN
OBJECTIVE: To report the technique, surgical approach, and postoperative features in horses treated via a 3-dimensional (3D) printed guide-assisted keratoma resection created using computed tomography (CT) or magnetic resonance imaging (MRI)-based segmentation. ANIMALS: Five client-owned horses. STUDY DESIGN: Short case series. METHODS: Horses were placed under general anesthesia for imaging (CT and MRI) and underwent a second anesthesia for surgery. Two horses had guides created from CT-based imaging, 3 horses had guides created from MRI. Various sized nonarbored hole saws were used to create accurate and precise portals for keratoma removal. Surgical sites were managed until keratinized granulation tissue had formed and the defect was sealed with an artificial hoof wall patch. RESULTS: All keratomas were successfully removed as a single piece either intact with the hoof wall or easily extracted after the hoof wall portal was created in a surgical time between 20 and 90 min. All CT created guides fitted without issue; MRI-created guides required minor adjustments with a rotary device for proper fit. All cases had minor debridement adjacent to P3 and circumferential lamellar tissue. All horses returned to previous level of performance 2 to 4 months postoperatively. CONCLUSION: Use of 3D printed guides led to accurate targeting of keratomas with small surgical portals and short surgical times. Due to challenges with MRI-based segmentation, CT is preferred.
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Pezuñas y Garras , Enfermedades de los Caballos , Queratosis , Animales , Enfermedades de los Caballos/diagnóstico por imagen , Enfermedades de los Caballos/patología , Enfermedades de los Caballos/cirugía , Caballos , Imagenología Tridimensional , Queratosis/patología , Queratosis/cirugía , Queratosis/veterinaria , Imagen por Resonancia Magnética/métodos , Imagen por Resonancia Magnética/veterinaria , Tomografía Computarizada por Rayos X/veterinariaRESUMEN
OBJECTIVE: To determine the influence of a custom 3D-printed guide for placement of cortical bone screws in the equine navicular bone. STUDY DESIGN: Ex vivo study. SAMPLE POPULATION: Eight pairs of normal adult equine forelimbs. METHODS: A 3.5 × 55 mm cortical screw was placed in the longitudinal axis of each intact navicular bone. Screws were placed with a 3D-printed guide (3D) in one bone and with a traditional aiming device (AD) in the contralateral bone within each pair. Duration of surgery and the number of fluoroscopy images were compared between techniques. Screw placement was subjectively evaluated by gross examination and scored by three boarded veterinary surgeons. RESULTS: The use of a 3D-printed guide reduced the duration of surgery by 6.6 min (±1.5 min) compared to traditional screw placement (20.7 min ± 4.8 min, p < .01). Fewer peri-operative fluoroscopic images were obtained when the 3D guide was used (18 images ± 2.6 images vs. 40 images ± 5.1, p < .01). No difference was detected in navicular screw placement. CONCLUSION: The use of a 3D guide decreased the time required to place screws and the number of intraoperative images taken without affecting screw placement in intact navicular bones. CLINICAL RELEVANCE: 3D-printed guides can aid in the study, practice, and execution of surgical procedures reducing surgical time and radiation exposure throughout the operative period achieving similar results to those obtained with a conventional approach.
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Tornillos Óseos/veterinaria , Hueso Cortical/cirugía , Caballos/cirugía , Impresión Tridimensional , Cirugía Veterinaria/métodos , Huesos Tarsianos/cirugía , Animales , Tornillos Óseos/estadística & datos numéricos , Cadáver , Femenino , Fluoroscopía/veterinaria , Masculino , Cirugía Veterinaria/instrumentación , Cirugía Veterinaria/estadística & datos numéricosRESUMEN
The objective of this study was to provide an overarching description of the inter-subject variability of the equine femur and tibia morphology using statistical shape modeling. Fifteen femora and fourteen tibiae were used for building the femur and tibia statistical shape models, respectively. Geometric variations in each mode were explained by biometrics measured on ±3 standard deviation instances generated by the shape models. Approximately 95% of shape variations within the population were described by 6 and 3 modes in the femur and tibia shape models, respectively. In the femur shape model, the first mode of variation was scaling, followed by notable variation in the femoral mechanical-anatomical angle and femoral neck angle in mode 2. Orientation of the femoral trochlear tubercle and femoral version angle were described in mode 3 and mode 4, respectively. In the tibia shape model, the main mode of variation was also scaling. In mode 2 and mode 3, the angles of the coronal tibial plateau and the medial and lateral caudal tibial slope were described, showing the lateral caudal tibial slope angle being significantly larger than the medial. The presented femur and tibia shape models with quantified biometrics, such as femoral version angle and posterior tibial slope, could serve as a baseline for future investigations on correlation between the equine stifle morphology and joint disorders due to altered biomechanics, as well as facilitate the development of novel surgical treatment and implant design. By generating instances matching patient-specific femorotibial joint anatomy with radiographs, the shape model could assist virtual surgical planning and provide clinicians with opportunities to practice on 3D printed models.
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Extremidad Inferior , Tibia , Animales , Caballos , Tibia/diagnóstico por imagen , Fémur/diagnóstico por imagen , Cuello Femoral , Fenómenos BiomecánicosRESUMEN
OBJECTIVE: To determine whether anesthesia type (sedation or general anesthesia) affects kid survival to discharge in caprine cesarean sections (C-sections). ANIMALS: Retrospective cohort of 99 caprine C-sections (2011-2021). PROCEDURES: All surgeries were performed via left flank laparotomy in right lateral recumbency. The number of kids alive at presentation, surgery, and discharge was recorded. Kids that were dead on presentation or euthanized intraoperatively were excluded. Goats were classified as "healthy" (American Society of Anesthesiologists status ≤ 2) or "sick" (≥ 3). RESULTS: Kid survival was significantly higher for C-sections performed under sedation (47/52 [90%]) than for C-sections performed under general anesthesia (16/24 [66%]; P = .004). Relative risk was 1.4 and odds ratio was 4.7. CLINICAL RELEVANCE: Performing C-sections in sedated goats may improve kid survival rates over those under general anesthesia.
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Cesárea , Cabras , Animales , Embarazo , Femenino , Estudios Retrospectivos , Cesárea/veterinaria , Cabras/cirugía , Anestesia General/veterinariaRESUMEN
OBJECTIVE: This study aims to quantitatively characterize the passive kinematics of the healthy, soft tissue-intact equine stifle to establish an objective foundation for providing insights into the etiology of stifle disorders and developing a possible surgical treatment for stifle degenerative disease. ANIMALS: 5 whole-horse specimens. PROCEDURES: Reflective markers with intracortical bone pins and a motion capture system were used to investigate the stifle joint kinematics. Kinematics of 5 whole-horse specimens euthanized within 2 hours were calculated for internal/external rotation, adduction/abduction, and cranial/caudal translation of the medial and lateral femoral condyles and estimated joint contact centroids as functions of joint extension angle. RESULTS: From 41.7° to 121.6° (mean ± SD, range of motion: 107.5° ± 7.2°) of joint extension, 13° ± 3.7° of tibial external rotation and 6° ± 2.7° of adduction were observed. The lateral femoral condyle demonstrated significantly greater cranial translation than the medial during extension (23.7 mm ± 9.3 mm vs. 14.3 mm ± 7.0 mm, P = .01). No significant difference was found between the cranial/caudal translation of estimated joint contact centroids in the medial and lateral compartment (13.3 mm ± 7.7 mm vs. 16.4 mm ± 5.8 mm, P = .16). CLINICAL RELEVANCE: The findings share similarities with kinematics for human knees and sheep and dog stifles, suggesting it may be possible to translate what has been learned in human arthroplasty to treatment for equine stifles.
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Caballos , Rodilla de Cuadrúpedos , Animales , Fenómenos Biomecánicos , Movimiento , Rango del Movimiento Articular , Rodilla de Cuadrúpedos/fisiologíaRESUMEN
OBJECTIVE: To develop 3D models of larynges to compare arytenoid abduction measurements between specimens and models, and to investigate the anatomic feasibility of placing an implant across the cricoarytenoid joint (CAJ) with or without arthrotomy. SAMPLES: Cadaveric equine larynges (n = 9). PROCEDURES: Equine larynges underwent sequential CT scans in a neutral position and with 2 arytenoid treatments: bilateral arytenoid abduction (ABD) and bilateral arytenoid abduction after left cricoarytenoid joint arthrotomy (ARTH). Soft tissue, cartilage, and luminal volume 3-dimensional models were generated. Rima glottidis cross-sectional area (CSA) and left-to-right quotient (LRQ) angles were measured on laryngeal specimens and models. Arytenoid translation, articular contact area, and length of modeled implants placed across the CAJ were measured on models. Data were analyzed using paired t test or ANOVA and Tukey's post hoc test or non-parametric equivalents (P < .05). RESULTS: ARTH CSA was larger for laryngeal specimens than models (P = .0096). There was no difference in all other measures of CSA and LRQ angle between treatment groups or between specimens and models. There was no difference between ABD and ARTH groups for arytenoid cartilage translation, contact area, and implant length. The articular contact area was sufficient for modeled implant placement across the CAJ with a narrow range of implant lengths (17.59 mm to 23.87 mm) across larynges with or without arthrotomy. CLINICAL RELEVANCE: These results support further investigation of a CT-guided, minimally invasive surgical procedure. Future studies will evaluate the outcomes of the new procedure for technical precision, biomechanical stability, and post-operative success rates for horses with recurrent laryngeal neuropathy (RLN).
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Laringoplastia , Laringe , Caballos , Animales , Cartílago Aritenoides/cirugía , Estudios de Factibilidad , Laringe/cirugía , Laringoplastia/veterinaria , Laringoplastia/métodos , ArticulacionesRESUMEN
OBJECTIVE: To evaluate the analgesic efficacy of lumbosacral intrathecal administration of 2% lidocaine in goats undergoing cesarean sections (C-sections). ANIMALS: 7 client-owned goats. PROCEDURES: Medical records were retrospectively reviewed to identify records of goats undergoing C-sections between January 2020 and November 2021 with intrathecal administration of lidocaine as the primary method of analgesia. Effect of analgesia, American Society of Anesthesiologists status, quality of surgery (determined based on lack of patient movement), mean surgical time, time to stand, and anesthetic complications were recorded. RESULTS: Intrathecal administration of preservative-free 2% lidocaine (1 mg/kg) at the lumbosacral space with the use of a 20-gauge 3.5-inch (0.9 X 90-mm) spinal needle under aseptic technique achieved effective analgesia in sedated goats by time of skin incision. Adequacy of analgesia was complete (failure to respond to needle-prick of skin or skin incision) in 6 of the 7 goats and moderate in 1 goat. Quality of surgery was adequate in all goats. Mean surgical time was 96 ± 20 minutes, and mean time to stand was 182 ± 61 minutes from the time of intrathecal administration. Complications included ruminal tympany, hypothermia, and partial blockade in 1 goat each. CLINICAL RELEVANCE: Results indicated that intrathecal administration of lidocaine as described in the present report provided adequate analgesia for C-sections in goats, with minimal complications, and quicker return to hindlimb motor function postoperatively than historically reported for epidurals.
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Analgesia , Lidocaína , Embarazo , Femenino , Animales , Lidocaína/uso terapéutico , Cesárea/veterinaria , Anestésicos Locales , Cabras/cirugía , Estudios Retrospectivos , Analgesia/veterinariaRESUMEN
OBJECTIVE: To report clinical experience using virtual surgical planning (VSP) and surgical application of 3D printed custom surgical guides to facilitate uni- and biapical correction of antebrachial deformities in dogs. ANIMALS: 11 dogs (13 antebrachial deformity corrections). PROCEDURES: Using CT-based bone models, VSP was performed, and surgical guides were designed and 3D printed. The guides were used to execute osteotomies and align bone segments. Postoperative CTs were obtained to compare limb alignment with the VSP. Long-term assessment of lameness and cosmesis were compared with preoperative status. RESULTS: Guides were successfully utilized and postoperative analysis was available for 10 of 13 deformities. Guides were abandoned in 2 deformities due to soft tissue tension. Evaluation of postoperative frontal, sagittal, axial, and translational limb alignment revealed that over 90% of parameters were within the acceptable range of ≤ 5° angulation and rotation or ≤ 5 mm of translation from the VSP. Lameness scores were improved in 7/8 deformities with associated preoperative lameness, and posture was improved in 10/10 deformities in which guides were deployed. Complications included reduced range of carpal motion (n = 2), implant sensitivity (n = 2), fracture (n = 1), and tendon laceration (n = 1). CLINICAL RELEVANCE: VSP and customized surgical guide application facilitated accurate antebrachial limb deformity correction in the majority of deformities in this case series. The use of VSP and 3D printed guides would appear to be a viable and accurate approach for correction of both uni- and biapical antebrachial deformities in dogs.
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Enfermedades de los Perros , Procedimientos de Cirugía Plástica , Perros , Animales , Miembro Anterior/cirugía , Cojera Animal , Osteotomía/veterinaria , Procedimientos de Cirugía Plástica/veterinaria , Impresión Tridimensional , Enfermedades de los Perros/cirugíaRESUMEN
OBJECTIVE: To quantify the translation and angular rotation of the distal sesamoid bone (DSB) using computed tomography (CT) and medical modeling software. SAMPLE: 30 thoracic limbs from equine cadavers. PROCEDURES: Partial (n = 12), full (8), and matched full and subsequently transected (10) thoracic limbs were collected. Bone volume CT images were acquired in three positions: extension (200° metacarpophalangeal angle), neutral (180°), and maximal flexion (110°). Mean translation and angular rotation of each DSB were recorded. Differences were determined with two-way ANOVA and post hoc Tukey's tests for pairwise comparisons; P value was set at < 0.05. RESULTS: Dorsal translation was significant during extension (1.4 ± 0.4 mm full limbs and 1.3 ± 0.2 mm partial limbs, P < 0.001). Distal translation was significant during extension (1.9 ± 0.4 mm full and 1.1 ± 0.4 mm partial) and flexion (5.4 ± 0.7 mm full and 6.22 ± 0.6 mm partial, P < 0.001). Rotation was significant (P < 0.001) about the mediolateral axis during extension (17.1° ± 1.4°) and flexion (2.6° ± 1.3°). Translation and rotation of the DSB were significantly different (P < 0.001) between full and partial limbs. CLINICAL RELEVANCE: This study provides the first quantification of translation and angular rotation of the DSB within the equine hoof. Partial limbs had significantly reduced movement compared to full limbs, suggesting that transection of flexor tendons alters distal thoracic limb kinematics. Further studies are required to determine if pathologic changes in the podotrochlear apparatus have an impact in clinical lameness outcomes.
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Miembro Anterior/fisiología , Caballos/fisiología , Huesos Sesamoideos/fisiología , Animales , Fenómenos Biomecánicos , Cadáver , Miembro Anterior/diagnóstico por imagen , Rango del Movimiento Articular , Tendones/patologíaRESUMEN
OBJECTIVE: To assess the feasibility and accuracy of using 2 methods for reduction and alignment of simulated comminuted diaphyseal tibial fractures in conjunction with 3-D-printed patient-specific pin guides. SAMPLE: Paired pelvic limbs from 8 skeletally mature dogs weighing 20 to 35 kg. METHODS: CT images of both tibiae were obtained, and 3-D reconstructions of the tibiae were used to create proximal and distal patient-specific pin guides. These guides were printed and used to facilitate fracture reduction and alignment in conjunction with either a 3-D-printed reduction guide or a linear type 1A external fixator. Postreduction CT images were used to assess the accuracy of pin guide placement and the accuracy of fracture reduction and alignment. RESULTS: The 3-D-printed guides were applied with acceptable ease. Guides for both groups were placed with minor but detectable deviations from the planned location (P = .01), but deviations were not significantly different between groups. Fracture reduction resulted in similar minor but detectable morphological differences from the intact tibiae (P = .01). In both groups, fracture reduction and alignment were within clinically acceptable parameters for fracture stabilization by means of minimally invasive plate osteosynthesis. CLINICAL RELEVANCE: Virtual surgical planning and fabrication of patient-specific 3-D-printed pin guides have the potential to facilitate fracture reduction and alignment during use of minimally invasive plate osteosynthesis for fracture stabilization.
Asunto(s)
Enfermedades de los Perros , Fracturas de la Tibia , Animales , Placas Óseas/veterinaria , Cadáver , Perros , Fijadores Externos , Fijación Interna de Fracturas/métodos , Fijación Interna de Fracturas/veterinaria , Humanos , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/veterinaria , Fracturas de la Tibia/diagnóstico por imagen , Fracturas de la Tibia/cirugía , Fracturas de la Tibia/veterinariaRESUMEN
The use of magnetic resonance imaging (MRI) has led to increased clinical and research applications using 3D segmentation and reconstructed volumetric data in musculoskeletal imaging. Lesions of the deep digital flexor tendon (DDFT) are a common pathology in horses undergoing MRI. Three-dimensional MRI reconstruction performed for volumetric tendon analysis in horses has not previously been documented. The aim of this proof-of-concept study was to evaluate the 3D segmentation of horses undergoing repeated MRI at several time points and to perform an analysis of the segmented DDFTs across time. MRI DICOM files were acquired from six horses undergoing repeated MRI examination of the foot for DDFT injury. Once segmented, volumetric tendon surface tessellation language (STL) files were created. Thickness and volumetric data were acquired for each tendon in addition to a tendon comparison across timepoints within each horse. Pearson correlation coefficients were calculated for comparison of MRI reports to computer analysis. There was a significant and positive correlation between MRI and medial record reports of clinical improvement or deterioration and computer analysis (r = 0.56, p = 0.01). The lower end range limit for tendon thickness varied between 0.16 and 1.74 mm. The upper end range limit for DDFT thickness varied between 4.6 and 23.6 mm. During tendon part comparison, changes in DDFT were reported between -3.0 and + 14.3 mm. Changes in DDFT size were non-uniform and demonstrated fluctuations throughout the tendon. The study was successful in establishing the volumetric appearance and thickness of the DDFT as it courses in the foot and tracking this over time. We encountered difficulties in accurate segmentation of the distal insertion of the DDFT as it blends with the distal phalanx. The data demonstrated that the DDFT can be segmented and volumetric studies based on size and shape can be performed using an in silico approach.
RESUMEN
OBJECTIVE: The aim of this study was to evaluate the surgical execution of a virtual surgical plan (VSP) with three-dimensional (3D) guides against a freehand approach in the equine navicular bone using an automated in silico computer analysis technique. STUDY DESIGN: Eight pairs of cadaveric forelimb specimens of adult horses were used in an ex vivo experimental study design with in silico modelling. Limbs received either a 3.5 mm cortical screw according to a VSP or using an aiming device. Using computed tomography and computer segmentation, a comparison was made between the executed screw and the planned screw using the Hausdorff distance (HD). RESULTS: Navicular bone mean HD registration error was -0.06 ± 0.29 mm. The VSP with 3D printing demonstrated significantly superior accuracy with a mean deviation of 1.19 ± 0.42 mm compared with aiming device group (3.53 ± 1.24 mm, p = 0.0018). The VSP group was 5.0 times more likely to result in a mean aberration of less than 1.0 mm (95% confidence interval, 0.62-33.4). A 3.5 mm screw with an optimal entry point can have a maximum deviation angle of 3.23 ± 0.07, 2.70 ± 0.06 and 2.37 ± 0.10 degrees in a proximal, dorsal and palmar direction respectively, prior to violating one of the cortical surfaces. CONCLUSION: Procedures performed using the 3D guides have a high degree of accuracy, with minimal mean deviations (<1 mm and <1 degree) of a VSP compared with those using the conventional aiming device. The use of VSP and the HD for evaluation of orthopaedic surgeries and outcome measures shows promise for simplifying and improving surgical accuracy.
Asunto(s)
Tornillos Óseos/veterinaria , Caballos/cirugía , Procedimientos Ortopédicos/veterinaria , Cirugía Asistida por Computador/veterinaria , Realidad Virtual , Animales , Femenino , Miembro Anterior/cirugía , Masculino , Procedimientos Ortopédicos/métodosRESUMEN
[This corrects the article DOI: 10.1371/journal.pone.0244208.].
RESUMEN
BACKGROUND: Spinal arthrodesis is a commonly performed spinal operation. Spinal arthrodesis can be complicated by pseudoarthrosis and resultant hardware failure. Static magnetic fields (SMF) have the ability to improve bone fusion. We seek to assess the feasibility of the construction and implantation of a lumbar interbody cage equipped with a SMF in a caprine model. METHODS: Six skeletally mature female Boer goats underwent a lateral approach for placement of an interbody graft at lumbar (L) 1-2 and 3-4. The goats were divided into 2 groups of 3 animals. The interbody graft contained a neodymium iron boron magnet in the experimental group and a nonmagnetic titanium sham in the control group. Both groups contained a synthetic bone graft. Blinded radiographic and histologic evaluation was performed at predetermined timepoints to assess degree of bony fusion and osseointegration. RESULTS: All 6 goats underwent successful placement of lumbar interbody grafts. At the 1-month postoperative computed tomography, 1 goat in the experimental group and 1 goat in the control group were noted to have dislodged their intervertebral cage. Qualitative radiographic and histologic evaluation identified enhanced bone formation, bone density, and osteointegration of the graft in the experimental group. CONCLUSIONS: A spinal interbody cage containing a neodymium iron boron magnet for the production of a local SMF is feasible. Preliminary data suggests enhanced bone formation, bone density, and osseointegration of the graft.