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1.
Behav Sleep Med ; : 1-14, 2024 Apr 09.
Artículo en Inglés | MEDLINE | ID: mdl-38592976

RESUMEN

OBJECTIVE: The aim of this study was to examine changes and the bi-directional relationship in sleep and movement, and health and well-being among new parents and differences by sex. METHODS: This secondary data analysis included both conditions from a randomized control trial to improve new parents'physical activity [PA] and recruited couples. Parents (n = 181, 117 couples represented 31.5 ± 4.4 years, 51.3% women, 83.3% White) completed questionnaires on regular overnight sleep duration, PA, mental health (perceived stress), physical health (physical quality of life [PQoL]), and well-being (life satisfaction) at 2-, 4-, 6-, and 8-month postpartum. Random-intercept cross-lagged panel models were stratified by sex to examine changes in sleep and PA with health and well-being across time. RESULTS: Sleep and stress were interrelated at different times for fathers (2 months), and mothers (8 months). Sleep and PQoL improved across time, with mothers reporting less sleep than fathers at 4 and 6 months. PQoL at 4 months was related to MVPA at 6-months. Life satisfaction and PA at 2 months was related to PA at 4 months. CONCLUSION: Mothers and fathers experienced different sleep and stress trajectories. Mental health improved postpartum with early connections to PA. Supporting the 24-hour movement behavior cycle and mental health across the parenthood transition may benefit couples.

2.
Ann Behav Med ; 57(4): 344-353, 2023 04 12.
Artículo en Inglés | MEDLINE | ID: mdl-36745018

RESUMEN

BACKGROUND: Understanding the predictors of moderate to vigorous physical activity (MVPA) during early postpartum is important to improve promotion efforts. Affect-related constructs are key predictors of MVPA but have limited research in mothers during the postpartum period. PURPOSE: To examine two affect-related constructs (affective response to exercise and affective judgments) as predictors of MVPA intention and behavior across three months, among a sample of new mothers. METHODS: Participants were 105 mothers (M age = 30.64 years; SD = 3.93) who completed measures during postpartum at 2-months post-birth of their first child. The affective response to exercise (assessed at baseline [2-months postpartum] during a submaximal treadmill test), affective judgments and intention (baseline, 6-weeks after baseline), and MVPA (baseline, 6- and 12-weeks after baseline) were assessed via self-report. RESULTS: Path analysis, using ordinary least squares regression, showed that the affective response during exercise was a significant predictor of intention (baseline, 6-weeks), as well as change in intention from baseline to 6-weeks. By contrast, affective judgments predicted intention at 6-weeks, but not at baseline or in the change model. Past MVPA did not moderate these findings, although the affective response during exercise also had a significant indirect effect on MVPA through intention at 6-weeks and 12-weeks. CONCLUSIONS: Interventions targeting women's affective response during exercise may be important during postpartum, perhaps through self-paced physical activity guidance. Affective judgments may not be predictive of MVPA, in part due to unanticipated changes during early postpartum leading to inaccurate expectations of the physical activity experience.


Understanding the predictors of moderate to vigorous physical activity (MVPA) during early postpartum is important to improve promotion efforts. Affect-related constructs are key predictors of MVPA but have limited research in mothers during the postpartum period. The purpose of this study was examine two affect-related constructs (affective response to exercise and affective judgments) as predictors of MVPA intention and behavior across three months, among a sample of new mothers. Participants were 105 mothers who completed measures of affective response to exercise (assessed at 2 months postpartum during a sub-maximal treadmill test), affective judgments and intention (2 months postpartum, and 6-weeks after), and MVPA (2 months postpartum, 6- and 12-weeks after). The affective response during exercise was a significant predictor of intention as well as change in intention over time. By contrast, affective judgments was a less reliable predictor across the study. Interventions targeting women's affective response during exercise may be important during postpartum, perhaps through self-paced physical activity guidance. Affective judgments may not be predictive of MVPA, in part due to unanticipated changes during early postpartum leading to inaccurate expectations of the physical activity experience.


Asunto(s)
Ejercicio Físico , Intención , Juicio , Adulto , Femenino , Humanos , Ejercicio Físico/psicología , Madres/psicología , Periodo Posparto/psicología , Lactante
3.
BMC Geriatr ; 23(1): 482, 2023 08 10.
Artículo en Inglés | MEDLINE | ID: mdl-37563553

RESUMEN

BACKGROUND: Hospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the study protocol for the Breaking Bad Rest Study, a randomized clinical trial aimed to promoting more movement in acute care using a novel device-based approach that could mitigate the impact of too much bedrest on frailty. METHODS: Fifty patients in a geriatric unit will be randomized into an intervention or usual care control group. Both groups will be equipped with an activPAL (a measure of posture) and StepWatch (a measure of step counts) to wear throughout their entire hospital stay to capture their physical activity levels and posture. Frailty will be assessed via a multi-item questionnaire assessing health deficits at admission, weekly for the first month, then monthly thereafter, and at 1-month post-discharge. Secondary measures including geriatric assessments, cognitive function, falls, and hospital re-admissions will be assessed. Mixed models for repeated measures will determine whether daily activity differed between groups, changed over the course of their hospital stay, and impacted frailty levels. DISCUSSION: This randomized clinical trial will add to the evidence base on addressing frailty in older adults in acute care settings through a devices-based movement intervention. The findings of this trial may inform guidelines for limiting time spent sedentary or in bed during a patient's stay in geriatric units, with the intention of scaling up this study model to other acute care sites if successful. TRIAL REGISTRATION: The protocol has been registered at clinicaltrials.gov (identifier: NCT03682523).


Asunto(s)
Fragilidad , Humanos , Anciano , Fragilidad/diagnóstico , Fragilidad/terapia , Cuidados Posteriores , Resultado del Tratamiento , Alta del Paciente , Terapia por Ejercicio/métodos , Calidad de Vida , Ensayos Clínicos Controlados Aleatorios como Asunto
4.
Compr Rev Food Sci Food Saf ; 21(3): 2873-2897, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-35279951

RESUMEN

Pulses provide economic and health benefits to people in many countries around the world; however, their adoption in western diets, particularly in processed and formulated foods, is limited. One strategy to increase the level of pulses in western diets is to improve pulse accessibility to the ready-to-eat (RTE) food market sector. Pulses have compositional and structural differences when compared to cereals and behave differently during processing. While there have been numerous studies on pulses processed using traditional processing methods, there are limited studies describing processing of pulses as a major ingredient in RTE forms such as flakes. To understand the full processing potential of pulses, systematic studies are required using commercial-scale RTE pilot processing equipment coupled with fundamental property determination techniques to evaluate the effects of processing and pulse material on pulse flake attributes. In-depth studies of pulse properties and their processability are likely to result in the production of high-quality pulse-based foods with superior health benefits. This review explores the current and potential opportunities for processing pulses with a focus on flake products. The roles of pulse type and major structure-forming components such as fiber, carbohydrates, and proteins on end-product quality of processed pulses are discussed.


Asunto(s)
Fibras de la Dieta , Grano Comestible , Fibras de la Dieta/análisis , Grano Comestible/química , Humanos
5.
J Sports Sci ; 39(13): 1461-1471, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33554750

RESUMEN

Family-based physical activity (PA) interventions have proven effective in modifying PA; yet, the underlying mechanisms are currently unclear. In this study, we follow-up upon prior trial data that showed changes to child moderate-to-vigorous PA (MVPA) as a result of a family education+planning intervention compared to an education-only condition. We examined parents' perceived family PA frequency, family PA social cognitions, and family PA habit over 26 weeks between the two conditions. One hundred and two parents (of children aged 6 to 12 yrs), were recruited through advertisements and randomized to either the planning + education condition (n = 52) or an education-only condition (n = 50). Self-reported family PA, and measures of theory of planned behaviour, planning intention, and habit were completed by the contact parent at baseline, six-week, 13-week, and 26-week time-periods. The education+planning intervention increased planning intention (p <.01) and family PA (p =.06) compared to the© education-only group. The effect of condition on the putative mediators did not explain these changes (all 95% CIs crossed 0), and family PA was associated with child MVPA only at 13 weeks (p <.01). Intervention 20 assignment had a small indirect effect on family PA (favouring©the education+planning group) via Habit. Perceived behavioural©control and habit were consistent predictors of family PA (p <.05), but not PA intention or planning intention (p >.05). The planning+education intervention showed improved family PA and planning intention, yet null mediation results suggest that other variables from the family system (e.g., child motivation, other parent's motivation and plans) are likely needed to fully understand the intervention effects. The promotion of perceived behavioural control and habit to assist in family PA is recommended for future research in this population.


Asunto(s)
Ejercicio Físico , Familia , Hábitos , Promoción de la Salud/métodos , Acelerometría , Adulto , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Autoinforme
6.
Women Health ; 61(1): 50-65, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33190626

RESUMEN

The transition to parenthood is associated with declines in moderate to vigorous physical activity (MVPA) and increases in light PA (LPA). One potential mechanism for this change in PA that occur at the onset of parenthood is housework. We examined housework load and PA levels of three cohorts of couples across 12 months recruited from Victoria, British Columbia, Canada between January 2007 and December 2011. Participants (N = 314; 102 not expecting a child, 136 expecting first-child, 76 expecting second child) completed baseline demographics and 7-day accelerometry, followed by assessments at 6 and 12 months. Hierarchical linear regression assessed the association between PA, housework, and perceptions of partner's workload. New fathers' but not new mothers' housework was positively related to their LPA at 12 months. Perceptions of partners' workload were positively related to new mothers LPA, and negatively related to new fathers MVPA at 12 months. Mediation analysis determined if perceived behavioral control accounts for the relationship between the discrepancy in housework between partners' PA. Results suggest that if a woman perceives their partner to do more housework their own PA increases, whereas for men their PA decreases. These findings highlight the importance of the division of housework on PA for both mothers and fathers.


Asunto(s)
Ejercicio Físico , Padre/psicología , Tareas del Hogar , Madres/psicología , Responsabilidad Parental , Acelerometría , Adulto , Canadá , Femenino , Humanos , Estilo de Vida , Masculino
7.
Rheumatology (Oxford) ; 59(5): 1128-1136, 2020 05 01.
Artículo en Inglés | MEDLINE | ID: mdl-31691832

RESUMEN

OBJECTIVE: Using a novel isotemporal substitution paradigm, this study aimed to estimate the cross-sectional associations of objectively measured sedentary behaviour and physical activity (PA) with cardiovascular risk factors among patients with SLE. METHODS: This was a cross-sectional study of adult SLE patients without documented cardiovascular disease (CVD). Cardiovascular risk factors were measured, including BMI, blood pressure, fasting glucose and lipid profile. Ten-year CVD risk was estimated using the American College of Cardiology/American Heart Association risk assessment tool. Time in sedentary behaviour, light PA, and moderate-vigorous PA (MVPA) was measured by accelerometry. We used three linear regression models-single-activity models, partition models, and isotemporal substitution models-to evaluate the associations of time spent at each movement intensity with each CVD risk variable. RESULTS: There were 100 SLE patients [92% female; mean (s.d.) age 52.4 (14.4) years]. Only 11 participants adhered to current PA recommendations (⩾150 MVPA min/week in ⩾10-min bouts). In isotemporal substitution, reallocating 10 min from sedentary behaviour to MVPA was associated with lower systolic (ß = -2.15 mmHg; P = 0.01) and diastolic blood pressure (ß = -1.56 mmHg; P = 0.01), as well as lower estimated 10-year CVD risk (RR 0.81, 95% CI 0.70, 0.93). Time reallocation from light PA to MVPA was associated with lower diastolic blood pressure (ß = -1.45 mmHg; P = 0.01) and lower 10-year CVD risk estimates (RR 0.80, 95% CI 0.69, 0.94). CONCLUSION: Given that reallocating time from other movement intensities to MVPA is associated favourably with lower cardiovascular risk, PA interventions are needed to address suboptimal MVPA levels among SLE patients.


Asunto(s)
Enfermedades Cardiovasculares/prevención & control , Ejercicio Físico/fisiología , Lupus Eritematoso Sistémico/complicaciones , Lupus Eritematoso Sistémico/diagnóstico , Conducta Sedentaria , Acelerometría/métodos , Adulto , Presión Sanguínea/fisiología , Índice de Masa Corporal , Enfermedades Cardiovasculares/etiología , Estudios Transversales , Femenino , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Prevención Primaria/métodos , Medición de Riesgo , Estados Unidos
8.
BMC Public Health ; 20(1): 1436, 2020 Sep 21.
Artículo en Inglés | MEDLINE | ID: mdl-32957959

RESUMEN

BACKGROUND: Regular physical activity (PA) is associated with many health benefits during childhood, and tracks into desirable PA patterns and health profiles in adulthood. Interventions designed to support these behaviours among young children are critical. Family-based interventions focusing on parent-child activities together (i.e., co-activity) among preschool-aged children are warranted. Targeting parental support practices can increase the frequency of co-activity, however interventions must move beyond merely building intention and planning skills for successful maintenance. Interventions designed to increase co-activity habit strength may facilitate the sustainability and thus impact child PA. The purpose of this study is to compare the effects of three intervention conditions designed to increase child PA through co-activity: a standard education condition (information about benefits), a planning (action planning, coping planning) + education condition and a habit (context-dependent repetition from prompts and cues) + planning +education condition. METHODS/DESIGN: A longitudinal three-arm parallel design randomized trial will compare three conditions over six months. Families are eligible if they have at least one child between 3y and 5y that is not meeting 60mins/day of moderate to vigorous physical activity (MVPA). The primary outcome (child MVPA) is assessed via accelerometry at baseline, six weeks, three months and six months (primary endpoint). Intervention materials targeting co-activity are delivered post baseline assessment, with booster sessions at six weeks and three months. Parental co-activity habit, parent-child co-activity and other behavioural constructs are also assessed via questionnaire at all measurement occasions. As tertiary outcomes, parental PA is measured via accelerometry and co-activity is measured via a Bluetooth-enabled proximity feature. A total of 106 families have been recruited thus far from the Greater Victoria region. The study is ongoing with a minimum target of 150 families and an anticipated recruitment completion date of August 2022. DISCUSSION: This protocol describes the implementation of a randomized trial evaluating the effectiveness of a habit formation group compared with a planning group and an education only group to increase child PA through targeting parent-child co-activity. This information could prove useful in informing public health initiatives to promote PA among families with preschool-aged children. TRIAL REGISTRATION: This trial was prospectively registered on clinicaltrials.gov in February 2016, identifier NCT03055871 .


Asunto(s)
Ejercicio Físico , Padres , Acelerometría , Adulto , Niño , Preescolar , Familia , Humanos , Motivación
9.
J Behav Med ; 43(2): 209-224, 2020 04.
Artículo en Inglés | MEDLINE | ID: mdl-31713079

RESUMEN

The purpose of this study was to examine the effect of two family interventions targeting inactive children on their parents' MVPA. Correlates of MVPA across the trial in the form of theory of planned behavior (TPB) and multi-process action control (M-PAC) were examined as exploratory outcomes. Parents (of children aged 6-12 years) were randomized to either a planning + education (n = 52) or an education only condition (n = 50) designed to improve child MVPA. Parental MVPA (accelerometry, self-report) was assessed at baseline, 6-week, 13-week, and 26-week time-periods. Parental MVPA increased from baseline to 26 weeks (p < .05), but there were no group differences. The TPB was unable to predict MVPA and application of M-PAC showed this was because nearly all participants possessed the intention to be active. Successful-compared to unsuccessful-intenders had stronger habit in four of the six tests employed (p < .05). Parent MVPA may benefit during a family-based intervention but the putative mediators of this increase are unclear.Registered trial clinicaltrials.gov #NCT01882192.


Asunto(s)
Ejercicio Físico , Responsabilidad Parental , Acelerometría , Niño , Familia , Femenino , Hábitos , Humanos , Masculino , Padres , Teoría Psicológica , Conducta Sedentaria , Autoinforme
10.
J Sci Food Agric ; 98(14): 5225-5234, 2018 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-29635691

RESUMEN

BACKGROUND: Lupin seeds are rich in proteins, which are utilized in the food industry. There is an increased interest in lupin research due to its association with health-related benefits, such as reduction of hypertension and hyperglycemia. However, studies on the peptides derived from lupin proteins are rare. RESULTS: Lupin protein hydrolysates (LPHs) were prepared by proteolysis using alcalase, trypsin and pepsin, respectively. All the hydrolysates demonstrated higher antioxidant and angiotensin I-converting enzyme (ACE) inhibitory activities compared to lupin proteins. The hydrolysates were fractionated into three fractions based on molecular weight (MW), and the peptides with MW < 3 kDa (LPH3) had the highest antioxidant and ACE inhibitory activities compared to other fractions. Cell model study revealed that LPH3 fraction had the highest protection against the generation of reactive oxygen species in HepG2 cells, which was associated with increased activities of superoxide dismutase and glutathione peroxidase through upregulation of SOD1, GPX1, GCLM, SLC7A11 and SRXN1 expression. CONCLUSIONS: The analysis of amino acid composition indicated that the peptides were characterized with high content of hydrophobic amino acids, which may be responsible for the greatest antioxidant activity. This study highlights the promising potential of lupin peptides as a functional ingredient in healthy foods. © 2018 Society of Chemical Industry.


Asunto(s)
Lupinus/química , Estrés Oxidativo/efectos de los fármacos , Péptidos/farmacología , Proteínas de Almacenamiento de Semillas/química , Inhibidores de la Enzima Convertidora de Angiotensina/química , Inhibidores de la Enzima Convertidora de Angiotensina/farmacología , Antioxidantes/química , Antioxidantes/farmacología , Células Hep G2 , Humanos , Hidrólisis , Peso Molecular , Pepsina A/química , Péptidos/química , Hidrolisados de Proteína/química , Hidrolisados de Proteína/farmacología , Proteínas de Almacenamiento de Semillas/farmacología , Semillas/química , Subtilisinas/química
11.
Psychooncology ; 26(12): 2186-2193, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-27886411

RESUMEN

BACKGROUND: Dog ownership has been associated with higher rates of physical activity (PA) in several populations but no study to date has focused on cancer survivors. The purpose of this study was to examine the associations between dog ownership and PA among cancer survivors and to examine correlates of dog ownership. METHODS: A stratified random sample of 2062 breast cancer survivors, prostate cancer survivors, and colorectal cancer survivors was mailed a questionnaire assessing PA, social cognitive, dog ownership, demographic, and medical variables. RESULTS: Overall, 25% of the sample was dog owners (DOs). There were no significant differences in moderate, vigorous, or total PA minutes between DOs and non-dog owners. There was a significant difference in light PA minutes in favor of DOs (153 vs 112 minutes; 95% CI = 4 to 77; P = .030), however, this was largely restricted to breast cancer survivors (143 vs 79 minutes; 95% CI = 25 to 102; P = .001) who also reported fewer vigorous PA minutes (18 vs 39 minutes; 95% CI = -42 to -1; P = .042). Survivors were more likely to be DOs if they had breast cancer (P = .054), a higher income (P = .021), radiation therapy (P = .029), chemotherapy (P = .010), were younger (P < .001), employed (P < .001), and a current smoker (P = .015). Few social cognitive variables were associated with DO. CONCLUSIONS: Dog ownership among cancer survivors was not associated with moderate-to-vigorous PA but was associated with light PA. Further research is necessary to determine if promoting dog ownership and dog walking among cancer survivors may increase PA and possibly improve health outcomes.


Asunto(s)
Neoplasias de la Mama/rehabilitación , Supervivientes de Cáncer/psicología , Neoplasias Colorrectales/rehabilitación , Perros , Ejercicio Físico/psicología , Neoplasias de la Próstata/rehabilitación , Caminata , Adulto , Anciano , Anciano de 80 o más Años , Animales , Neoplasias de la Mama/mortalidad , Neoplasias de la Mama/psicología , Supervivientes de Cáncer/estadística & datos numéricos , Neoplasias Colorrectales/mortalidad , Neoplasias Colorrectales/psicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Nueva Escocia/epidemiología , Propiedad , Neoplasias de la Próstata/mortalidad , Neoplasias de la Próstata/psicología , Factores Socioeconómicos , Encuestas y Cuestionarios , Caminata/estadística & datos numéricos
12.
BMC Public Health ; 17(1): 875, 2017 Nov 09.
Artículo en Inglés | MEDLINE | ID: mdl-29121884

RESUMEN

BACKGROUND: Identifying critical life transitions in people's physical activity behaviors may illuminate the most opportune intervention apertures for chronic disease prevention. A substantive evidence base now indicates that parenthood is one of these critical transition points for physical activity decline. This study will examine whether a brief theory-based intervention can prevent a decline in physical activity among new parents over 6 months following intervention. This study protocol represents the first dyad-based physical activity initiative in the parenthood literature involving both mothers and fathers; prior research has focused on only mothers or only fathers (albeit limited), and has shown only short-term changes in physical activity. This study will be investigating whether a theory-based physical activity intervention can maintain or improve moderate to vigorous intensity physical activity measured via accelerometry of new parents over a 6 month period following intervention compared to a control group. METHODS: This study is a 6-month longitudinal randomized controlled trial. Parents are measured at baseline (2 months postpartum) with two assessment points at 6 weeks (3.5 months postpartum) and 3 months (5 months postpartum) and a final follow-up assessment at 6 months (8 months postpartum). The content of the theory-based intervention was derived from the results of our prior longitudinal trial of new parents using an adapted theory of planned behavior framework to predict changes in physical activity. RESULTS: A total of 152 couples have been recruited to date. Sixteen couples dropped out after baseline and a total of 88 couples have completed their 6-month measures. DISCUSSION: If the intervention proves successful, couple-based physical activity promotion efforts among parents could be a promising avenue to pursue to help mitigate the declines of physical activity levels during parenthood. These findings could inform public health materials and practitioners. TRIAL REGISTRATION: This trial has been registered with the Clinical Trials Registry maintained by the National Library of Medicine at the National Institutes of Health on April 19, 2014. The registration ID is NCT02290808 .


Asunto(s)
Ejercicio Físico , Promoción de la Salud/métodos , Padres/psicología , Acelerometría , Femenino , Humanos , Estudios Longitudinales , Masculino , Evaluación de Programas y Proyectos de Salud , Teoría Psicológica
13.
J Behav Med ; 40(6): 978-988, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-28631101

RESUMEN

Exergames may be one way to increase child physical activity, but long term adherence has seen little research attention. The primary objective of this study was to evaluate the usage of an exergame bike in comparison to a stationary bike in front of a TV across 3-months within a family home environment among children aged 10-14 years old. Seventy-three inactive children were recruited through advertisements and randomized to either the exergame condition (n = 39) or the standard bike condition (n = 34). Weekly bike use was recorded in a log-book. Both groups declined in bike use over time (t = 3.921, p < .01). Although the exergame group reported higher use (t = 2.0045, p < .05), this was most prominent during the first week. Overall, these results do not support exergames as a standalone physical activity intervention, and suggest that short duration examinations of exergames may be misleading.


Asunto(s)
Ciclismo/psicología , Ejercicio Físico/psicología , Conducta Sedentaria , Adolescente , Niño , Terapia por Ejercicio/métodos , Femenino , Humanos , Masculino , Actividad Motora/fisiología , Factores de Tiempo , Juegos de Video
14.
Psychol Health Med ; 22(7): 872-878, 2017 08.
Artículo en Inglés | MEDLINE | ID: mdl-27998180

RESUMEN

The objective of this study was to examine the effectiveness of a 12 week weight loss intervention within a commercial fitness centre on body weight, moderate to vigorous physical activity (MVPA), dietary intake, and behavioural regulations for exercise and healthy eating. Using a quasi-experimental design, the intervention group received weekly coaching sessions and bi-weekly seminars designed to increase MVPA and improve dietary intake. Outcome variables were assessed at three time points over a six month period. Results showed a significant interaction for body weight (p = .04) and dietary changes (p < .05) following the weight loss challenge but were not maintained across the six month period. Changes in behavioural regulations favoured the intervention condition. Results imply that a 12 week weight loss challenge within a commercial fitness centre may be effective at prompting short-term weight loss and support the internalization of behavioural regulations specific to healthy eating and exercise.


Asunto(s)
Redes Comunitarias , Ejercicio Físico , Conductas Relacionadas con la Salud , Motivación , Pérdida de Peso , Adulto , Femenino , Centros de Acondicionamiento , Humanos , Masculino , Persona de Mediana Edad , Obesidad , Adulto Joven
15.
Prep Biochem Biotechnol ; 47(8): 789-794, 2017 Sep 14.
Artículo en Inglés | MEDLINE | ID: mdl-28636439

RESUMEN

In this study, the effect of Bacillus amyloliquefaciens-produced ß-mannanase on the nutrient diffusion (release) and antioxidant activity of spent brewer yeast (SBY) was investigated. Three pretreatments were performed: (1) autolysis at 50°C for 24 h; (2) autolysis at 50°C for 24 h, with the addition of ß-mannanase during the autolysis; (3) autolysis at 50°C for 24 h, and the ß-mannanase was added for another 12 h treatment. The pretreatments with the addition of ß-mannanase caused significant cell wall degradation, markedly increased the yield of SBY extracts. More importantly, this study found that polysaccharides were degraded to be oligosaccharides with a considerable reduction in molecular weights. Meanwhile, pretreatment with the enzyme also exhibited a higher antioxidant activity in SBY extract compared to autolysis itself. The current study indicated that pretreatment (3) had a better effect than pretreatment (2) in terms of improving in antioxidant activity in SBY extract. These improved characteristics of SBY extracts isolated through enzymatic treatment appear to show promising features for their prospective use as natural functional agents.


Asunto(s)
Bacillus amyloliquefaciens/enzimología , Saccharomyces cerevisiae/metabolismo , beta-Manosidasa/metabolismo , Antioxidantes/metabolismo , Hidrólisis , Oligosacáridos/metabolismo , Polisacáridos/metabolismo
16.
Lipids Health Dis ; 15: 86, 2016 Apr 28.
Artículo en Inglés | MEDLINE | ID: mdl-27121709

RESUMEN

BACKGROUND: Deep frying in oil is a popular cooking method around the world. However, the safety of deep-fried edible oil, which is ingested with fried food, is a concern, because the oil is exposed continuously to be re-used at a high temperature, leading to a number of well-known chemical reactions. Thus, this study investigates the changes in energy metabolism, colon histology and gut microbiota in rats following deep-fried oil consumption and explores the mechanisms involved in above alterations. METHODS: Deep-fried oil was prepared following a published method. Adult male Wistar rats were randomly divided into three groups (n = 8/group). Group 1: basal diet without extra oil consumption (control group); Group 2: basal diet supplemented with non-heated canola oil (NEO group); Group 3: basal diet supplemented with deep-fried canola oil (DFEO group). One point five milliliters (1.5 mL) of non-heated or heated oil were fed by oral gavage using a feeding needle once daily for 6 consecutive weeks. Effect of DFEO on rats body weight, KEGG pathway regarding lipids metabolism, gut histology and gut microbiota were analyzed using techniques of RNA sequencing, HiSeq Illumina sequencing platform, etc. RESULTS: Among the three groups, DFEO diet resulted in a lowest rat body weight. Metabolic pathway analysis showed 13 significantly enriched KEGG pathways in Control versus NEO group, and the majority of these were linked to carbohydrate, lipid and amino acid metabolisms. Comparison of NEO group versus DFEO group, highlighted significantly enriched functional pathways were mainly associated with chronic diseases. Among them, only one metabolism pathway (i.e. glycerolipid metabolism pathway) was found to be significantly enriched, indicating that inhibition of this metabolism pathway (glycerolipid metabolism) may be a response to the reduction in energy metabolism in the rats of DFEO group. Related gene analysis indicated that the down-regulation of Lpin1 seems to be highly associated with the inhibition of glycerolipid metabolism pathway. Histological analysis of gastrointestinal tract demonstrated several changes induced by DFEO on intestinal mucosa with associated destruction of endocrine tissue and the evidence of inflammation. Microbiota data showed that rats in DFEO group had the lowest proportion of Prevotella and the highest proportion of Bacteroides among the three groups. In particular, rats in DFEO group were characterized with higher presence of Allobaculum (Firmicutes), but not in control and NEO groups. CONCLUSION: This study investigated the negative effect of DFEO on health, in which DFEO could impair glycerolipid metabolism, destroy gut histological structure and unbalance microbiota profile. More importantly, this is the first attempt to reveal the mechanism involved in these changes, which may provide the guideline for designing health diet.


Asunto(s)
Culinaria/métodos , Microbioma Gastrointestinal/efectos de los fármacos , Metabolismo de los Lípidos/efectos de los fármacos , Consorcios Microbianos/efectos de los fármacos , Aceites de Plantas/efectos adversos , Animales , Peso Corporal/efectos de los fármacos , Colon/efectos de los fármacos , Colon/patología , Masculino , Consorcios Microbianos/genética , Aceites de Plantas/química , Aceite de Brassica napus , Ratas Wistar
17.
Plant Foods Hum Nutr ; 71(3): 277-85, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27323763

RESUMEN

The instability and low bioavailability of polyphenols limit their applications in food industries. In this study, epigallocatechin gallate (EGCG) and soybean seed ferritin deprived of iron (apoSSF) were fabricated as a combined double shell material to encapsulate rutin flavonoid molecules. Firstly, due to the reversible assembly characteristics of phytoferritin, rutin was successfully encapsulated within apoSSF to form a ferritin-rutin complex (FR) with an average molar ratio of 28.2: 1 (rutin/ferritin). The encapsulation efficiency and loading capacity of rutin were 18.80 and 2.98 %, respectively. EGCG was then bound to FR to form FR-EGCG composites (FRE), and the binding number of EGCG was 27.30 ± 0.68 with a binding constant K of (2.65 ± 0.11) × 10(4) M(-1). Furthermore, FRE exhibited improved rutin stability, and displayed prolonged release of rutin in simulated gastrointestinal tract fluid, which may be attributed to the external attachment of EGCG to the ferritin cage potentially reducing enzymolysis in GI fluid. In summary, this work demonstrates a novel nanocarrier for stabilization and sustained release of bioactive polyphenols.


Asunto(s)
Catequina/análogos & derivados , Preparaciones de Acción Retardada/química , Ferritinas/química , Glycine max/química , Nanoestructuras/química , Rutina/química , Disponibilidad Biológica , Catequina/química , Catequina/farmacocinética , Preparaciones de Acción Retardada/farmacocinética , Ferritinas/farmacocinética , Tracto Gastrointestinal/efectos de los fármacos , Hierro/química , Hierro/farmacocinética , Polifenoles/química , Polifenoles/farmacocinética , Rutina/farmacocinética
19.
BMC Public Health ; 15: 1011, 2015 Oct 05.
Artículo en Inglés | MEDLINE | ID: mdl-26437939

RESUMEN

BACKGROUND: Physical activity is associated with the reduction of several chronic conditions in adults. Additionally, physical activity is extremely important for children for their development and cognitive functioning and also to create a physically active lifestyle that continues into adulthood. Despite the known benefits of physical activity, only one in five adults are achieving the public health recommendations of 150 minutes of moderate-to-vigorous physical activity per week and only 13 % of boys and 6 % of girls between the ages of 5 and 17 years are meeting the guidelines of 60 minutes per day. This study aims to evaluate whether a planning condition improves adherence to regular physical activity compared to an education-only control condition among families. Families are eligible if there is at least one child between the ages of 6 and 12 years who is not meeting the Canadian Physical Activity Guidelines. METHODS/DESIGN: A six-month longitudinal randomized controlled trial will be used to compare the two conditions. Materials will be delivered at baseline with 'booster' sessions at six weeks and three months. Participants will be assessed at baseline and at six months with a fitness test, as well as questionnaires and accelerometery at baseline, six weeks, three months and six months. A total of 137 families have been recruited thus far from Greater Victoria. This study is ongoing and recruitment will continue until December 2015 with the target goal of reaching 160 families. DISCUSSION: This protocol describes the implementation of a randomized controlled trial that utilizes planning strategies to try and increase physical activity among families. Research findings could be useful in public health in providing effective strategies to families to help decrease sedentary lifestyles. Additionally, findings may help to inform future interventions aimed at increasing physical activity among families. TRIAL REGISTRATION: This trial was registered on June 5, 2012 with the Clinical Trials Registry maintained by the National Library of Medicine at the National Institutes of Health. The registration ID is NCT01882192.


Asunto(s)
Ejercicio Físico , Familia , Conductas Relacionadas con la Salud , Promoción de la Salud/métodos , Estilo de Vida , Conducta Sedentaria , Canadá , Niño , Servicios de Planificación Familiar , Femenino , Educación en Salud , Humanos , Intención , Estudios Longitudinales , Masculino , Proyectos de Investigación , Encuestas y Cuestionarios , Estados Unidos , Victoria
20.
COPD ; 12(5): 539-45, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25774558

RESUMEN

Little is known about longitudinal trends in objectively measured physical activity (PA) during and after pulmonary rehabilitation (PR) for individuals with Chronic Obstructive Pulmonary Disease (COPD). The purpose of this study was to examine the PA trajectories of patients with COPD during and after PR and whether demographic, clinical, or program characteristics differed across these trajectories. The study was approved by Research Ethics Boards at all participating institutions, and written informed consent was obtained from each participant prior to study inclusion. COPD patients (N = 190) completed a questionnaire and wore a pedometer for 7 days at baseline, end of PR, and 3 and 9 months after completing PR. Latent class growth analyses showed that two distinct PA trajectories emerged. Active Maintainers averaged 9177 steps/day at baseline, and maintained this level throughout the assessment and post rehabilitation period. In contrast, Inactive Maintainers averaged 3133 steps/day at baseline, which also remained stable during and after PR. Follow-up analyses showed the Inactive Maintainers were more likely to be retired from work and have lower baseline scores for their stress tests and 6-minute walk tests compared to Active Maintainers (all p < 0.05). These results suggest that two distinct steps/day trajectories exist for COPD patients during and after completing PR that are partially explained by specific demographic and clinical characteristics.


Asunto(s)
Terapia por Ejercicio , Actividad Motora , Enfermedad Pulmonar Obstructiva Crónica/fisiopatología , Enfermedad Pulmonar Obstructiva Crónica/rehabilitación , Acelerometría , Anciano , Prueba de Esfuerzo , Femenino , Conductas Relacionadas con la Salud , Humanos , Masculino , Persona de Mediana Edad , Jubilación , Encuestas y Cuestionarios , Factores de Tiempo , Capacidad Vital
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