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1.
Epilepsy Behav ; 125: 108364, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34731723

RESUMEN

From August 27-28, 2020 the Epilepsy Foundation hosted the Pipeline Conference, exploring emerging issues related to antiepileptic drug and device development. The conference featured epilepsy therapeutic companies and academic laboratories developing drugs for focal epilepsies, innovations for rare and ultra-rare diseases, and devices both in clinical trials and approved for use. In this paper, we outline the virtual presentations by the authors, including novel data from their development pipeline.


Asunto(s)
Epilepsias Parciales , Epilepsia , Preparaciones Farmacéuticas , Anticonvulsivantes/uso terapéutico , Epilepsias Parciales/tratamiento farmacológico , Epilepsia/tratamiento farmacológico , Humanos
2.
Epilepsy Behav ; 111: 107189, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32563052

RESUMEN

On May 22-24, 2019, the 15th Antiepileptic Drug and Device (AEDD) Trials Conference was held, which focused on current issues related to AEDD development from preclinical models to clinical prognostication. The conference featured regulatory agencies, academic laboratories, and healthcare companies involved in emerging epilepsy therapies and research. The program included discussions around funding and support for investigations in epilepsy and neurologic research, clinical trial design and integrated outcome measures for people with epilepsy, and drug development and upcoming disease-modifying therapies. Finally, the conference included updates from the preclinical, clinical, and device pipeline. Summaries of the talks are provided in this paper, with the various pipeline therapeutics in the listed tables to be outlined in a subsequent publication.


Asunto(s)
Anticonvulsivantes/uso terapéutico , Ensayos Clínicos como Asunto , Congresos como Asunto/tendencias , Desarrollo de Medicamentos/tendencias , Epilepsia/tratamiento farmacológico , Animales , Ensayos Clínicos como Asunto/métodos , Aprobación de Recursos , Desarrollo de Medicamentos/métodos , Epilepsia/diagnóstico , Epilepsia/genética , Florida , Pruebas Genéticas/métodos , Pruebas Genéticas/tendencias , Humanos , Tamizaje Masivo/métodos , Tamizaje Masivo/tendencias , National Institute of Neurological Disorders and Stroke (U.S.)/tendencias , Estados Unidos
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