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J Clin Microbiol
; 47(2): 466-8, 2009 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19091815
RESUMEN
No mutations were detected in the hemagglutinin gene of influenza A/H3N2 virus isolates from patients undergoing short-term amantadine treatment. However, genetic changes occurred after serial passage in either MDCK or MDCK-SIAT1 cells. Our results showed that only a few mutations were observed in MDCK-SIAT1-passaged isolates in the presence of amantadine.