The impact of frailty in aortic valve surgery.

BACKGROUND: Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and individual features of frailty in cardiac aortic valve surgery. METHODS: Prospective study. From May-2014 to February-2016, we collected 200 patients who underwent aortic valve replacement, either surgically or transcatheter. At 1-year follow-up, quality of life measurements were recorded using the EQ-5D (EuroQol). Univariate and multivariate analyses correlated preoperative condition, features of frailty and predicted risk scores with mortality, morbidity and quality of life at 1 year of follow-up. RESULTS: Mean age 78.2y, 56%male. Mean-preoperative-scores: FRAIL scale 1.5(SD 1.02), STS 2.9(SD 1.13), BI 93.8(SD 7.3), ESlog I 12.8(SD 8.5) and GS 7.3 s (SD 1.9). Morbidity at discharge, 6 m and 1 year was 51, 14 and 28%. Mortality 4%. Survival at 6 m/ 1-y was 97% / 88%. Complication-rate was higher in TAVI group due to-vascular complications. Renal dysfunction, anemia, social dependence and GS slower than 7 s were associated with morbidity. On multivariate analysis adjusted STS, BI and GS speed were statistically significant. Quality of life at 1-year follow-up adjusted for age and prosthesis type showed a significant association with STS and FRAIL scale scores. CONCLUSIONS: Frailty increases surgical risk and is associated with higher morbidity. Preoperative GS slower 7 s, and STS and FRAIL scale scores seem to be reliable predictors of quality of life at 1-year follow-up.

[Associated factors and descriptive analysis of healthcare-related infective endocarditis in a tertiary reference hospital]. / Factores asociados y análisis descriptivo de la endocarditis infecciosa adquirida en el entorno hospitalario de un centro terciario de referencia.

INTRODUCTION AND OBJECTIVES: The primary aim of this study was to evaluate associated factors, clinical features and prognosis of healthcare-related infective endocarditis cases compared with community-acquired and intravenous drug user-related episodes. Changes in the distribution of healthcare-related infective endocarditis were also analysed over time in our setting. METHODS: A prospective, observational, comparative study was performed. We included all the cases of infective endocarditis from January 2003 to June 2010, which were then classified into 2 groups: group 1: community-acquired and intravenous drug user origin, and group 2: nosocomial and non-nosocomial healthcare-related cases. The episodes were classified into 2 periods: period I: January/2003-June/2006 and period II: July/2006-June 2010. Univariate and multivariate analyses were performed. RESULTS: A total of 212 cases were included (group 1: 138, group 2: 74). The variables of age (risk ratio 1.026; 95%CI, 1.003 to 1.049), Charlson index (risk radio 1.242; 95%CI, 1.067 to 1.445), and previous heart surgery (risk ratio 2.522; 95%CI, 1.353 to 4.701) were independently associated with healthcare-related infective endocarditis on multivariate analysis. A non-significant increase was observed in healthcare-related cases of infective endocarditis in period II (40/104; 38.4% vs. 34/108; 31.4%). CONCLUSIONS: The recent increase in healthcare-related infective endocarditis seems to be associated with the use of invasive procedures in elderly patients with prosthetic cardiac valve, and those with a greater number of underlying diseases, especially patients with chronic renal failure on haemodialysis.

Activation of a code sepsis in the emergency department is associated with a decrease in mortality. / La activación de un código sepsis en urgencias se asocia a una menor mortalidad.

OBJECTIVES: To evaluate the impact of a code sepsis (CS) activation, complying with recommendations, the evolution of patients with severe sepsis in the emergency room and determine independent factors associated to mortality. METHOD: All patients attending the emergency room with severe sepsis during a 6-month period were included. Complying with Surviving Sepsis Campaign recommendations, patients' average stay, intensive care admissions and 30-day mortality were assessed. Two groups were compared: CS activation (A) and no activation (NA). RESULTS: A total of 114 episodes were found, 61.4% belonging to group A and 38.6% to NA. Patients in group A presented hypotension more frequently (61.5% vs 34.4%; P=.005). Patients in group NA more frequently had lactate levels of >3mmol/L (48.3% vs 80%; P=.01), and abdominal focus of sepsis (34.3% vs 13%; P=.01). In group A, blood cultures were more frequently drawn in the first hour (95% vs 41.7%; P<.001), early antibiotic was administered (76.9% vs 25%; p=.005) and fluid replacement carried out (54.5% vs 18.2%; P=.01). Global achievement of CS objectives was higher in group A (31.4% vs 9.1%; P=.006). In group NA more patients were admitted to the intensive care unit (10% vs 36.4%; P<.001), had longer average stays (10.2 days SD 6.9 vs 14.4 days SD 5.8; P<.001) and a higher mortality rate (4.3% vs 34.1%; P<.001). CRP>200mg/l (OR 33.7; P<.001) and the no activation of CS (OR 13.3; p=.001) resulted in being independent factors associated with mortality. CONCLUSIONS: The implementation of a CS improves compliance with SSC recommendations and decreases intensive care admissions, average stays and mortality.

A cross-sectional study on the level of severity of dental caries in adults / Estudio transversal sobre nivel de severidad de caries dental en adultos

Introduction: Oral diseases affect some 3.9 billion people worldwide, the most prevalent are dental caries, gingivitis, and periodontitis. Untreated dental caries lesions affect 35% of the population. Objective: To determine the level of severity of dental caries lesions in adults treated at public dental services in the cities of Asunción and Pirayú, Paraguay, in 2 017. Material and Methods: Sociodemographic and clinical variables of oral health status were evaluated by means of a cross-sectional study using consecutive sampling. Two dentists were calibrated to perform the oral examination. Caries experience was evaluated using the DMF-T index. The Chi square test and Fisher's exact test were applied, with a confidence level of 95%. Results:333 subjects with a mean age of 35 years participated in the study, 77.2% were females, and 64.0% did not have access to private health care services. The DMF-T index was 11.43 (SD=6.7); 12.6% obtained a very low level, 35.7% low level, 41.7% had a medium level, and 9.9% had a high level in the DMF-T index. The DMF-T index was significantly higher in females (p=0.001), in the age range of 50 to 59 years (p<0.001), in those who did not have access to private health services (p=0.008), in those who reported a negative self-evaluation of their oral health (p=0.04), in those with a normal molar ratio (p=0.023) and a very severe aesthetic index (p<0 . 0 01). Conclusion: The general level of severity of global caries was medium and associated with sociodemographic and clinical variables.

Introducción: Las enfermedades orales afectan a 3,9 billones de personas a nivel mundial, siendo las más prevalentes la caries dental, la gingivitis y periodontitis; afectando al 35% de la población las lesiones de caries dental no tratadas. Objetivo: Determinar el nivel de severidad de lesiones de caries dental en adultos que acuden a servicios odontológicos públicos en las ciudades de Asunción y Pirayú, en el Paraguay, en el año 2017. Material y Métodos: Estudio transversal donde se evaluaron variables sociodemográficas y clínicas del estado de salud oral. El muestreo fue de casos consecutivos. Dos odontólogos fueron calibrados para realizar el examen oral. La experiencia de caries fue evaluada mediante el índice CPO-D. Se aplicaron las pruebas Chi cuadrado y Test exacto de Fisher, con un nivel de confianza del 95%. Resultados: Participaron del estudio 333 sujetos, con edad promedio de 35 años, el 77,2% mujeres y el 64,0% no tenía acceso a servicios de salud privado. El índice CPO-D fue de 11,43 (DE = 6,7). El 12,6% obtuvo un nivel muy bajo, el 35,7% nivel bajo, el 41,7% tuvo nivel medio y el 9,9% nivel alto del CPO-D, siendo significativamente más elevado en mujeres (p= 0, 0 01), en la edad de 50 a 59 años (p<0,001), en aquellos que no cuentan con acceso a servicios de salud privado (p=0,008), los que relataron una autoevaluación negativa de su salud bucal (p=0,04), los que tenían una relación molar normal (p=0,023) e índice de estética muy grave (p<0, 0 01). Conclusión: El nivel general de severidad de caries global fue medio, se asoció con variables sociodemográficas y clínicas.

Association between self-assessment and clinical oral health status in adults, Paraguay / Asociación entre la autoevaluación y el estado clínico de salud oral en adultos, Paraguay

Introduction: Oral health can be defined as the absence of pathologies and disorders that affect the stomatognathic system. Objetives: This study aimed to determine the characteristics of self-assessment oral health status, in the clinical experience of dental caries, periodontal status, periodontal fixation loss and to investigate the association between self-reported and clinical oral health status among Paraguayans adults during early 2017. Material and Methods: The design is cross-sectional. Two dentists carried out the oral examinations following the recommendations of the World Health Organization (WHO). Results: There were 333 adult participants with a mean age of 35 ± 13 years. Most (77.2%) of the participants were female. Missing teeth (5.32±6), filled teeth (3.56±4), and decayed teeth (2.55±3) were also detected. Almost half (48.0%) of participants had dental calculus, while 5.8% had a periodontal pocket and 48.6% periodontal fixation loss. The self-perception of oral health was poor in 12.3% of participants, fair in 29.8%, normal in 31.8%, good in 16.2%, and excellent in 9.9%. Oral health self-assessment was positive in 58.0% and negative in 42.0%. A statistically significant difference was found when comparing the DMFT index according to self-perception of oral health, the score being higher in those who had negative self-perception; obtaining similar results in the decayed component. Conclusion: Negative oral health self-perception was associated with a high DMFT index, of this, the decayed component was the only one that presented statistically significant differences.

Introducción: La salud bucodental puede ser definida como la ausencia de patologías y trastornos que afectan el sistema estomatognático. Objetivos: Este estudio tuvo como objetivo determinar las características de la autoevaluación del estado de salud bucal, en la experiencia clínica de la caries dental, el estado periodontal, la fijación de la pérdida periodontal e investigar la asociación entre el estado de salud bucal autoinformado y clínico entre los adultos paraguayos a principios de 2017. Material y Métodos: El diseño es transversal. Dos odontólogos fueron calibrados para el examen bucal, siguiendo las recomendaciones de la Organización Mundial de la Salud (OMS). Resultados: Participaron 333 sujetos, el promedio de edad fue de 34.93 (DE=12.64) años, 77.2% eran mujeres. El 21.1% de las piezas dentarias estaban perdidas, el 12.2% obturadas y el 9.2% cariadas. El 48.0% presentó cálculo dental, 5.8% el bolsa periodontal y el 48.6% pérdida de fijación. La autopercepción de salud bucal fue para el 12.3% pobre, el 29.8% regular, el 31.8% normal, el 16.2% buena y el 9.9% excelente. Tuvieron una autoevaluación de su salud oral positiva el 58.0% y negativa el 42.0%. Se encontró diferencia estadísticamente significativa al comparar el DMFT index según la autopercepción de salud oral, siendo mayor el puntaje en los negativos; obteniéndose resultados similares con el componente cariado. Conclusión: La autopercepción de salud oral negativa se asoció con un elevado DMFT index, de este, el componente cariado fue el único que presentó diferencias estadísticamente significativas.

Validation of the oral health impact profile in spanish for paraguayan adults (OHIP-14Py) / Validación del perfil de impacto de salud oral en español para adultos paraguayos (OHIP-14Py)

Objetive: The objective of this study was to culturally adapt and validate the short version of the Oral Health Impact Profile (OHIP) instrument into Spanish for use by Paraguayan adults who attended dental clinics. Material and methods: The design was a cross-sectional observational study based on Classical Test Theory (CTT). The original English language version was subjected to a forward-backward translation processes; a calibration of the examiners and pilot test were performed. The questionnaire was applied by dentists through interviews; the same dentists also made the oral examination. The dimensionality of the questionnaire was evaluated using Confirmatory Factorial Analysis (CFA). The total and item-total internal consistencies were evaluated using Cronbach's alpha. To evaluate the discriminating validity, the Mann-Whitney and Kruskal-Wallis tests were used. Spearman's correlation analysis was used to measure convergent validity for total-dimension, self-assessment of oral health, and dental caries experience index with the DMFT Index. Results: Three-hundred-thirty-three patients participated in the study. The CFA indicates the Paraguayan's OHIP (OHIP-14Py) is considered a multi-dimensional instrument. The Cronbach's alpha values were appropriate for both the total (α=0.061) and for item total (α=0.80) correlation. The OHIP-14Py discriminated for the variable self-perception of oral health (p=0.001), symptoms of the temporomandibular joint (TMJ) (p=0.026), need of upper dental prosthesis (p=0.001), need of lower dental prosthesis (p=0.001), and ≥20 teeth healthy (p=0.001). For measuring convergent validity, all coefficients of correlation were statistically significant (p=0.001). Conclusion: The OHIP-14Py is a reliable and valid questionnaire for the evaluation of oral health-related quality of life in Paraguayan adults.

Objetivo: El objetivo del estudio fue adaptar culturalmente y validar el instrumento Perfil de Impacto de Salud Oral (OHIP) en la versión corta de 14 ítems en español, en adultos paraguayos que acudieron a consultorios odontológicos durante el primer trimestre del año 2017. Material y Métodos: El diseño del estudio fue transversal, basado en la Teoría Clásica de los Test (TCT). La versión original en inglés fue sometida al proceso de traducción-retraducción. Se realizó calibración de exa-minadores y prueba piloto. El cuestionario fue aplicado por odontólogos mediante entrevista, quienes además realizaron examen bucal. Se evaluó la dimensionalidad del cuestionario mediante el Análisis Factorial Confirmatorio (AFC). La consistencia interna fue evaluada mediante Alfa de Cronbach (α) para total e ítem-total. Se evaluó la validez discriminante utilizando las pruebas de Mann-Whitney y Kruskal-Wallis, validez convergente utilizando correlación de Spearman para total-dominio, autoevaluación del estado de salud oral e índice de experiencia de caries CPO-D. Resultados: Participaron del estudio 333 pacientes de 18 a 59 años. El AFC se consideró al instrumento multidimensional. Para el total α=0,861 y para correlación ítem-total al suprimir cada elemento α=0,80 siendo todos adecuados. Discriminó para las variables autoevaluación de salud bucal (p=0,001), síntomas de ATM (p=0,026), necesidad de prótesis superior (p=0,001) e inferior (p=0,001) y ≥20 dientes sanos (p=0,001). Todos los coeficientes de correlación de Spearman resultaron estadísticamente significativos con p=0,001. Conclusión: El OHIP-14Py es un cuestionario fiable y válido para la evaluación de la calidad de vida relacionada con la salud oral en adultos paraguayos.

Calidad de vida relacionada con salud oral: impacto de diversas situaciones clínicas odontológicas y factores socio-demográficos: revisión de la literatura / Quality of life related to oral health: impact of various socio-demographic factors and dental clinical situations: review of literature

La calidad de vida relacionada con salud oral es un concepto relativamente nuevo que considera la autopercepción del individuo acerca de su salud, como un componente a ser considerado además del examen clínico odontológico. Se planteó una revisión de la literatura, con el objetivo de buscar evidencia científica sobre el impacto que tienen en la vida diaria diversas patologías orales y diversos factores socio-demográficos, en estudios que utilizaron el cuestionario Perfil de Impacto de Salud Oral, en los últimos 5 años (2009-2013). Se concluye que dicho instrumento es válido para el diagnóstico, plan de tratamiento y pronóstico del paciente, sirviendo como guía en el conocimiento de la percepción del paciente acerca de la afectación en su vida diaria, pudiendo de esta manera prever la adherencia del mismo.

The quality of life related to oral health is a relatively new concept that considers the self-perception of the individual about their health as a component to be further considered the dental clinical examination. A narrative review was proposed with the aim of seeking scientific evidence of the impact on daily life various oral pathologies and various socio-demographic factors in studies using Impact Profile Questionnaire Oral Health in the last 5 years (2009-2013). We conclude that the instrument is valid for the diagnosis, treatment plan and prognosis of the patient, serving as a guide in understanding the patient's perception about the effect on their daily lives, and can thus provide the same grip.