Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 14 de 14
Filtrar
1.
Turk J Pediatr ; 47(1): 89-91, 2005.
Artículo en Inglés | MEDLINE | ID: mdl-15884638

RESUMEN

Intracranial calcification, periosteal proliferation and microcephaly, which represent the clinical features of the congenital cytomegalovirus infection, can also be seen in a rare disorder named Raine syndrome. This clinical entity has been reported in eight families so far. Here, we report a new patient with clinical features of the Raine syndrome associated with cytomegalovirus infection. Although this may be a chance association only, the condition raised the question of whether early intrauterine CMV infection may contribute to the Raine phenotype.


Asunto(s)
Anomalías Múltiples/patología , Anomalías Craneofaciales/patología , Infecciones por Citomegalovirus/patología , Osteosclerosis/patología , Anomalías Múltiples/etiología , Huesos/anomalías , Calcinosis/complicaciones , Infecciones por Citomegalovirus/complicaciones , Femenino , Humanos , Recién Nacido , Osteosclerosis/diagnóstico por imagen , Radiografía , Cráneo/anomalías , Cráneo/diagnóstico por imagen , Columna Vertebral/anomalías , Columna Vertebral/diagnóstico por imagen , Síndrome
2.
Turk J Pediatr ; 47(3): 272-4, 2005.
Artículo en Inglés | MEDLINE | ID: mdl-16250315

RESUMEN

Brucellosis is a zoonotic infection, transmitted to humans primarily by consumption of unpasteurized milk and milk products. Transmission by blood transfusion is possible but very unusual. Herewith we present two newborns with positive blood cultures for Brucella melitensis after exchange transfusions. However, the standard tube agglutination titers against Brucella were not elevated and the newborns did not develop brucellosis. It is suggested that, in areas endemic for brucellosis, blood donors should be questioned about symptoms of brucellosis, and if suspected, serological tests for brucellosis should be indicated before blood transfusion. At the same time, the prevalence of the disease among animals should be reduced with effective animal disease control programs.


Asunto(s)
Brucella melitensis/aislamiento & purificación , Reacción a la Transfusión , Adulto , Donantes de Sangre , Humanos , Recién Nacido , Ictericia/terapia , Masculino
3.
J Pediatr Endocrinol Metab ; 16(3): 457-9, 2003 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-12705373

RESUMEN

Rubinstein-Taybi syndrome is a genetic syndrome characterized by broad thumbs and big toes, growth retardation, mental deficiency and dysmorphic facies. We report the association of Rubinstien-Taybi syndrome with congenital hypothyroidism.


Asunto(s)
Hipotiroidismo Congénito , Hipotiroidismo/diagnóstico , Síndrome de Rubinstein-Taybi/diagnóstico , Humanos , Recién Nacido , Masculino , Tamizaje Masivo , Factores de Riesgo , Hormonas Tiroideas/sangre
4.
Turk J Pediatr ; 46(2): 191-3, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-15214756

RESUMEN

Asymmetric crying facies is caused by congenital hypoplasia or agenesis of the depressor anguli oris muscle. Associations of this facial defect with major congenital anomalies have been reported, most commonly in the cardiovascular system and less frequently involving the genitourinary, musculoskeletal, cervicofacial, respiratory, and rarely, the endocrine system. CATCH 22 is a medical acronym for cardiac defects, abnormal facies, thymic hypoplasia, cleft palate and hypocalcemia and a variable deletion on chromosome 22q11. The deletion within chromosme region of 22q11 may occur in patients with dysmorphologic and cardiological syndromes: DiGeorge syndrome, velo-cardiofacial syndrome and conotruncal anomaly face syndrome. We report a newborn infant who had asymmetric crying facies associated with congenital hypoparathyroidism, severe neonatal hypocalcemia and tetralogy of Fallot. Genetic confirmation of chromosome 22q11 deletion was made.


Asunto(s)
Deleción Cromosómica , Cromosomas Humanos Par 22/genética , Llanto , Asimetría Facial/genética , Facies , Hipoparatiroidismo/complicaciones , Asimetría Facial/complicaciones , Humanos , Hipocalcemia/complicaciones , Hipoparatiroidismo/congénito , Recién Nacido , Masculino , Tetralogía de Fallot/complicaciones
6.
Ann Trop Paediatr ; 27(1): 31-7, 2007 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-17469730

RESUMEN

AIM: To measure maternally derived measles antibodies in sera of premature infants at birth and seropositivity rates in early infancy in a rural area of central Turkey. METHODS: 65 premature and 24 full-term infants born in Erciyes University Hospital and their mothers were recruited to a longitudinal, prospective study. The infants were divided into three groups by gestational age: group A, <33 weeks; group B, 33-37 weeks; group C, >37 weeks. For specific analyses, the groups were subdivided into groups Al, B1 and C1 (infants of naturally immunised mothers) and A2, B2 and C2 (infants of vaccinated mothers). Blood samples were obtained from mothers and infants after delivery. The infants were re-evaluated at 2, 4 and 6 months of age. RESULTS: Of 25 mothers, 20.3% were seronegative for measles antibodies. Twenty of the mothers had not been vaccinated. The percentages of seronegative infants at birth were 24.2% (n=8), 12.5% (n=4) and 0% (n=0) in groups A, B and C, respectively. No infants were seronegative at birth in Al, B1 or C1. Mean levels of antimeasles antibodies in all naturally immunised mothers were significantly higher than in vaccinated mothers. Antibody levels in all infants decreased rapidly with increasing age. Gestational age at birth [beta=0.179, t=3.359, 95% confidence interval (CI) 0.0001-0.0001, p<0.05], birthweight (beta=0.637, t=9.691, 95% CI 0.057-0.086, p<0.05) and maternal naturally immunised status (beta=0.168, t=2.825, 95% CI 0.002-0.014, p<0.05) were significantly associated with antibody levels after birth. In all groups of naturally immunised mothers, the percentages of seronegative infants were significantly lower than in vaccinated mothers at birth and at 2, 4 and 6 months of age. CONCLUSION: The current recommendation to immunise all infants at 9 months of age might require revision for premature infants, especially those whose mothers have vaccination-induced immunity.


Asunto(s)
Anticuerpos Antivirales/sangre , Recien Nacido Prematuro/inmunología , Virus del Sarampión/inmunología , Femenino , Edad Gestacional , Humanos , Inmunidad Innata , Inmunidad Materno-Adquirida , Recién Nacido , Estudios Longitudinales , Masculino , Vacuna Antisarampión/inmunología
7.
Mycoses ; 49(6): 484-92, 2006 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-17022766

RESUMEN

The use of oral nystatin to prevent fungal colonisation and infection in neonates in the Neonatal Intensive Care Unit (NICU) is still an open question and not yet recommended as a standard of care. To determine whether prophylactic oral nystatin results in a decreased incidence of invasive candidiasis in the newborn infants, a total of 3991 infants were divided randomly into two groups. Group A infants (n = 1995), only those neonates who were identified as yeast carriers (oral moniliasis) were treated with oral nystatin. Group B infants, all neonates who were admitted to the unit received oral nystatin, was routinely administered three times a day. Group A was divided into groups A1 and A2 (who were treated only if identified as yeast carriers). Urine and rectal cultures were taken on admission and then weekly thereafter. There were 215 (14.2%), 27 (5.6%) and 36 (1.8%) patients positive for invasive candidiasis in groups A1, A2 and B respectively. Oral nystatin prophylaxis significantly reduced the invasive candidiasis (P = 0.004) in extremely low-birth weight (ELBW) and very low-birth weight (VLBW) infants. Prophylactic administration of oral nystatine to the ELBW and VLBW infants results in a decreased risk of invasive candidiasis.


Asunto(s)
Antifúngicos/uso terapéutico , Candidiasis/prevención & control , Enfermedades del Recién Nacido/prevención & control , Unidades de Cuidado Intensivo Neonatal , Nistatina/uso terapéutico , Administración Oral , Profilaxis Antibiótica , Antifúngicos/administración & dosificación , Candida/aislamiento & purificación , Candidiasis/sangre , Candidiasis/líquido cefalorraquídeo , Candidiasis/orina , Femenino , Humanos , Recién Nacido , Masculino , Nistatina/administración & dosificación , Faringe/microbiología , Recto/microbiología
8.
Am J Perinatol ; 23(6): 335-9, 2006 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-16841278

RESUMEN

Severity of respiratory distress syndrome (RDS) and mechanical ventilation may affect the endogenous cortisol secretion in preterm infants. The aim of this study was to compare the serum cortisol concentrations of a relatively large and mature group of preterm infants with RDS who are ventilated or nonventilated and control preterm infants without RDS. Infants (group I) of comparable gestational ages without RDS served as controls. Infants with RDS who did not need ventilator support and surfactant therapy were considered to have mild RDS (group II). Those requiring mechanical ventilation and surfactant therapy were considered to have severe RDS (group III). Serum cortisol levels were determined after birth and on day 3 of life. The study groups consisted of 79 preterm infants with gestational ages ranging from 31 to 36 weeks, and birthweights ranging from 1086 to 1685 g. All preterm infants showed high cortisol levels after delivery regardless of respiratory distress (group I, n = 25, 34.1 +/- 10.7 microg/dL; group II, n = 23, 33.6 +/- 12.0 microg/dL; and group III, n = 31, 36.4 +/- 12.3 microg/dL). In group III, the cortisol levels (50.8 +/- 16.8 microg/dL) were higher than in group II (40.4 +/- 10.5 microg/dL) and in controls (22.0 +/- 7.2 microg/dL), and the cortisol levels of controls were lower than in group II on day 3 of life. Although the cortisol levels in severe and mild RDS infants increased significantly from their corresponding levels on day 1, they decreased in controls. The cortisol levels on day 3 of life were not significantly different in infants with poor outcome compared with infants with better outcome. Severity of RDS and mechanical ventilation were related to serum cortisol levels of preterm infants. Our study suggests that large and mature preterm infants who are ventilated and/or more severely ill release more cortisol than those less severely ill.


Asunto(s)
Hidrocortisona/sangre , Recién Nacido de Bajo Peso/sangre , Recien Nacido Prematuro/sangre , Respiración Artificial , Síndrome de Dificultad Respiratoria del Recién Nacido/sangre , Síndrome de Dificultad Respiratoria del Recién Nacido/terapia , Peso al Nacer , Estudios de Casos y Controles , Femenino , Humanos , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Tiempo de Internación , Masculino , Síndrome de Dificultad Respiratoria del Recién Nacido/patología , Índice de Severidad de la Enfermedad , Turquía
9.
Ann Trop Paediatr ; 23(4): 301-4, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14738578

RESUMEN

Congenital hypothyroidism is often associated with other congenital anomalies. In some instances it is difficult to differentiate congenital hypothyroidism from Werdnig-Hoffmann's disease. We report a case of congenital hypothyroidism associated with Werdnig-Hoffmann's disease that appears to be the first of its kind in the literature.


Asunto(s)
Hipotiroidismo Congénito , Atrofias Musculares Espinales de la Infancia/complicaciones , Humanos , Hipotiroidismo/patología , Recién Nacido , Masculino , Atrofias Musculares Espinales de la Infancia/patología
10.
Eur J Pediatr ; 161(11): 614-5, 2002 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-12424588

RESUMEN

UNLABELLED: The syndrome of haemolysis, elevated liver enzymes and low platelet count (HELLP syndrome) is a severe form of pre-eclampsia and eclampsia associated with poor maternal and neonatal outcome. We report here the case of an infant born to a mother with HELLP syndrome. The infant was initially diagnosed as having nephrotic syndrome but after a follow-up period of 25 days proteinuria and oedema had disappeared. CONCLUSION: to our knowledge, transient proteinuria with maternal HELLP syndrome has not been previously described in the literature.


Asunto(s)
Síndrome HELLP/complicaciones , Resultado del Embarazo , Proteinuria/etiología , Adulto , Femenino , Humanos , Embarazo , Factores de Tiempo
11.
Pediatr Int ; 44(6): 652-7, 2002 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-12421264

RESUMEN

BACKGROUND: Septic arthritis is an uncommon, but serious disorder in neonates. Most patients survive with permanent handicaps. Due to the rarity of this condition in neonates and paucity of signs and symptoms, the diagnosis of septic arthritis in newborns is more difficult than in older children. METHODS: Septic arthritis or suppurative arthritis is an infection of the joint by a variety of microorganisms, including bacteria, viruses, mycobacteria and fungi. Purulent synovial fluid, positive culture and positive Gram stain were accepted as a gold standard for exact diagnosis. Fourteen neonates who were followed-up in a neonatal intensive care unit, with septic arthritis, were included in a study based on a review of medical reports and a long-term clinical and radiological follow-up. Clinical symptoms, bacteriology, risk factors and outcomes are discussed. RESULTS: Staphylococcus aureus was the predominant causative organism. Risk factors for septic arthritis were prematurity (4/14), umbilical catheterization or venous catheterization (3/14), sepsis (3/14), perinatal asphyxia (2/14) and difficult birth (1/14). All cases of septic arthritis in neonates were improved without squealae except in two patients. One patient died and one patient had severe squealae. In these two patients, the duration of disease from clinical onset to initiation of therapy was long. CONCLUSIONS: The most important prognostic factor in predicting a favorable outcome in neonatal septic arthritis is early diagnosis and therapy. When appropriate treatment is delayed, catastrophic sequelae are inevitable. Early diagnosis of the condition and rapid removal of pus are mandatory for the survival of the joint. Long-term follow-up may reveal effects of epiphyseal damage, early degenerative changes and limitation of the range of motion.


Asunto(s)
Artritis Infecciosa/diagnóstico , Artritis Infecciosa/microbiología , Femenino , Estudios de Seguimiento , Humanos , Lactante , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Masculino , Factores de Riesgo , Infecciones Estafilocócicas/diagnóstico , Turquía/epidemiología
12.
Pediatr Dermatol ; 20(6): 529-30, 2003.
Artículo en Inglés | MEDLINE | ID: mdl-14651576

RESUMEN

Pseudomonas aeruginosa bacteremia or sepsis often occurs in hospitals, affecting mainly children with underlying disease. Ecthyma gangrenosum is classically considered a pathognomonic sign of sepsis by P. aeruginosa. The harlequin baby, a severe variant of ichthyosis, occurs rarely, and these infants are at high risk of cutaneous infections and sepsis. We herein report a harlequin baby who developed ecthyma gangrenosum.


Asunto(s)
Ictiosis Lamelar/diagnóstico , Infecciones por Pseudomonas/diagnóstico , Enfermedades Cutáneas Bacterianas/diagnóstico , Diagnóstico Diferencial , Resultado Fatal , Femenino , Gangrena , Humanos , Ictiosis Lamelar/complicaciones , Ictiosis Lamelar/patología , Recién Nacido , Infecciones por Pseudomonas/complicaciones , Infecciones por Pseudomonas/patología , Pseudomonas aeruginosa/aislamiento & purificación , Enfermedades Cutáneas Bacterianas/complicaciones , Enfermedades Cutáneas Bacterianas/patología
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA