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Cornea ; 39(8): 1017-1019, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32282358

RESUMEN

PURPOSE: This study compares the quality of donor corneal tissue stored in Optisol-GS and Cornea Cold. METHODS: Seventeen pairs of donor corneas were obtained from an eye bank. One of each pair was stored in Cornea Cold or Optisol-GS. Endothelial cell loss (ECL), central corneal thickness (CCT), and endothelial cell density (ECD) were measured at 7 and 21 days of storage. Qualitative metrics were evaluated by using a slit lamp. RESULTS: At days 7 and 21, there were no observed differences in qualitative corneal health of the samples. There were no statistical differences in the mean ECL at 7 and 21 days between the 2 groups (P = 0.07 and P = 0.50, respectively). At 7 days, the mean CCT was 644 ± 52 µm in the Cornea Cold group and 591 ± 64 µm in the Optisol-GS group (P = 0.001). At 21 days, CCT was 714 ± 55 µm in the Cornea Cold group and 708 ± 58 µm in the Optisol-GS group (P = 0.70). The mean ECD was not statistically different between the groups (P = 0.56 at 7 days and P = 0.14 at 21 days). CONCLUSIONS: Storage of corneal donor tissue in the Optisol-GS and Cornea Cold storage media resulted in statistically comparable ECL and ECD for up to 21 days. CCT was higher in Cornea Cold at 7 days, but this discrepancy disappeared at 21 days.


Asunto(s)
Córnea/cirugía , Trasplante de Córnea/métodos , Bancos de Ojos , Soluciones Preservantes de Órganos/farmacología , Preservación de Órganos/métodos , Donantes de Tejidos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Recuento de Células , Supervivencia Celular , Niño , Preescolar , Córnea/diagnóstico por imagen , Femenino , Humanos , Masculino , Persona de Mediana Edad , Microscopía con Lámpara de Hendidura , Adulto Joven
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