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1.
Delineating the role of cooperativity in the design of potent PROTACs for BTK.
Proc Natl Acad Sci U S A
; 115(31): E7285-E7292, 2018 07 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-30012605
2.
Preparation, characterization, and pharmacodynamic study on deep second degree burns of total flavonoids composite phospholipids liposome gel of Oxytropis falcata Bunge.
Drug Dev Ind Pharm
; 46(12): 2000-2009, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33095085
3.
Scalable, Electrochemical Oxidation of Unactivated C-H Bonds.
J Am Chem Soc
; 139(22): 7448-7451, 2017 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28510449
4.
Electrochemically Enabled, Nickel-Catalyzed Amination.
Angew Chem Int Ed Engl
; 56(42): 13088-13093, 2017 10 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28834098
5.
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Angew Chem Int Ed Engl
; 55(33): 9601-5, 2016 08 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27355874
6.
Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
Bioorg Med Chem Lett
; 23(6): 1727-31, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23414806
7.
Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.
Bioorg Med Chem Lett
; 23(10): 3059-63, 2013 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23566514
8.
Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively.
bioRxiv
; 2023 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36711980
9.
Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents.
Bioorg Med Chem Lett
; 22(22): 6832-8, 2012 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23046961
10.
Identification of a novel homozygous LAMB3 mutation in a Chinese male with junctional epidermolysis bullosa and severe urethra stenosis: A case report.
Front Genet
; 13: 965375, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36246619
11.
Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure-Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H1 Receptor Inverse Agonist.
J Med Chem
; 63(13): 7268-7292, 2020 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32462865
12.
Structural Basis for Achieving GSK-3ß Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
J Med Chem
; 62(21): 9600-9617, 2019 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31535859
13.
Inhibitory effects of 16-hydroxycleroda-3,13(14)E-dien-15-oic acid on superoxide anion and elastase release in human neutrophils through multiple mechanisms.
Eur J Pharmacol
; 586(1-3): 332-9, 2008 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-18367166
14.
Therapeutic Effect and Mechanism of Oxytropis falcata Gel on Deep Second-Degree Burn in Rats.
Evid Based Complement Alternat Med
; 2017: 3729547, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29259644
15.
Ru/Ni Dual Catalytic Desulfinative Photoredox Csp2-Csp3 Cross-Coupling of Alkyl Sulfinate Salts and Aryl Halides.
Org Lett
; 19(24): 6566-6569, 2017 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29182291
16.
Enhanced performance of CH3NH3PbI3-x Cl x perovskite solar cells by CH3NH3I modification of TiO2-perovskite layer interface.
Nanoscale Res Lett
; 11(1): 316, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27356563
17.
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.
Sci Rep
; 6: 30859, 2016 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27527709
18.
Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism.
ACS Chem Biol
; 11(9): 2529-40, 2016 09 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27391855
19.
One-pot oxidation and rearrangement of propargylamines and in situ pyrazole synthesis.
Org Lett
; 16(16): 4146-9, 2014 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25069029
20.
Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors.
J Med Chem
; 57(23): 10072-9, 2014 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25375838