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BMJ Case Rep ; 20152015 Nov 11.
Artículo en Inglés | MEDLINE | ID: mdl-26561223

RESUMEN

A 74-year-old woman with end-stage renal disease presented with clinical symptoms of encapsulating peritoneal sclerosis 2 years after switching from peritoneal dialysis to haemodialysis. Imaging revealed a large cystic structure in her abdomen and her final diagnosis was made by exploratory laparotomy. A 10 cm×15 cm fibrous rind was excised from the peritoneum and the patient was subsequently started on tamoxifen 20 mg daily and prednisone 20 mg daily. Given her reduction in clinical symptoms and concerns about the long-term effects of corticosteroids, prednisone was tapered and she remained on tamoxifen monotherapy. 1 year postsurgery, she presented with symptoms of nausea, vomiting and anorexia. A repeat CT of the abdomen confirmed a recurrence of encapsulating peritoneal sclerosis. Prednisone and tamoxifen were restarted at increased dosages of 25 and 40 mg daily, respectively. The patient's symptoms were ameliorated within 2 weeks of drug therapy modification.


Asunto(s)
Fallo Renal Crónico/terapia , Diálisis Peritoneal Ambulatoria Continua/métodos , Fibrosis Peritoneal/diagnóstico , Anciano , Antiinflamatorios/uso terapéutico , Femenino , Humanos , Inmunosupresores/uso terapéutico , Náusea/etiología , Fibrosis Peritoneal/tratamiento farmacológico , Prednisona/uso terapéutico , Tamoxifeno/uso terapéutico , Tomografía Computarizada por Rayos X , Resultado del Tratamiento , Vómitos/etiología
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